{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,19]],"date-time":"2026-05-19T20:16:27Z","timestamp":1779221787621,"version":"3.51.4"},"reference-count":33,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2025,10,3]],"date-time":"2025-10-03T00:00:00Z","timestamp":1759449600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100010269","name":"Wellcome Trust","doi-asserted-by":"publisher","award":["205039\/Z\/16\/Z"],"award-info":[{"award-number":["205039\/Z\/16\/Z"]}],"id":[{"id":"10.13039\/100010269","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acad Dermatol Venereol"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>The long\u2010term socioeconomic impact of atopic dermatitis (AD) is poorly understood.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>To examine if childhood AD is associated with labor market and relationship outcomes in adulthood.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This nationwide registry\u2010based Danish cohort study included children born between 1973 and 1991: 8409 with hospital\u2010diagnosed AD before age 18 (baseline) and 853,228 without. A sibling cohort (5119 with AD; 6352 without) was used to control for family\u2010related confounding. The main outcomes were earned income, long\u2010term unemployment, single partnership status and childlessness by age 30. We used linear regression for income and Poisson regression for binary outcomes, adjusted for income, sex, calendar year, comorbidities and childhood socioeconomic status.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Children with AD had slightly lower income (adjusted mean percentile difference\u2009\u2212\u20091.2) and higher risk of long\u2010term unemployment (adjusted relative risk [aRR] 1.11; 95% CI: 1.05\u20131.17) by age 30, though the absolute difference was &lt;1%. AD was not associated with secondary labor market outcomes (e.g. health\u2010related work absenteeism), except for disability pension, but the RR decreased from 1.55 to 1.15 (95% CI: 1.02\u20131.30) when adjusting for comorbidities. By age 30, 22.1% with AD remained single versus 19.4% without (aRR 1.11; 95% CI: 1.06\u20131.15), with stronger associations among males, those with severe eczema, hand\/contact dermatitis or low maternal education (aRRs up to 1.41). AD was not associated with childlessness at age 30 (57.7% vs. 56.7%; aRR 1.01; 95% CI: 1.00\u20131.03), but a 2.5% absolute difference appeared by age 40. In the sibling analysis, most associations diminished.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>\n                      Moderate\u2010to\u2010severe childhood\n                      <jats:styled-content style=\"fixed-case\">AD<\/jats:styled-content>\n                      was not linked to labor market outcomes, apart from disability pensions, likely driven by comorbidities. The probability of partnership or parenthood was reduced in specific subgroups. Confounding from family\u2010related factors cannot be excluded. Nevertheless, the results underscore the importance of considering patients' broader life situations to support them through adulthood.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jdv.70085","type":"journal-article","created":{"date-parts":[[2025,10,3]],"date-time":"2025-10-03T13:15:53Z","timestamp":1759497353000},"page":"79-89","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Long\u2010term socioeconomic outcomes in Danish children with moderate\u2010to\u2010severe atopic dermatitis"],"prefix":"10.1111","volume":"40","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5527-0698","authenticated-orcid":false,"given":"Sigrun Alba Johannesdottir","family":"Schmidt","sequence":"first","affiliation":[{"name":"Department of Clinical Epidemiology and Center for Population Medicine Aarhus University Hospital and Aarhus University  Aarhus Denmark"},{"name":"Department of Dermatology Aarhus University Hospital  Aarhus Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D\u00f3ra K\u00f6rmendin\u00e9","family":"Farkas","sequence":"additional","affiliation":[{"name":"Department of Clinical Epidemiology and Center for Population Medicine Aarhus University Hospital and Aarhus University  Aarhus Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0593-9925","authenticated-orcid":false,"given":"Mette S.","family":"Deleuran","sequence":"additional","affiliation":[{"name":"Department of Dermatology Aarhus University Hospital  Aarhus Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christian","family":"Vestergaard","sequence":"additional","affiliation":[{"name":"Department of Dermatology Aarhus University Hospital  Aarhus Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4299-7040","authenticated-orcid":false,"given":"Henrik T.","family":"S\u00f8rensen","sequence":"additional","affiliation":[{"name":"Department of Clinical Epidemiology and Center for Population Medicine Aarhus University Hospital and Aarhus University  Aarhus Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Niels","family":"Skipper","sequence":"additional","affiliation":[{"name":"Department of Economics and Business Economics Aarhus University  Aarhus Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sin\u00e9ad M.","family":"Langan","sequence":"additional","affiliation":[{"name":"Faculty of Epidemiology and Population Health London School of Hygiene and Tropical Medicine  London UK"},{"name":"Health Data Research  UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,10,3]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140\u20106736(20)31286\u20101"},{"key":"e_1_2_12_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/s13555\u2010022\u201000819\u20106"},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jid.2016.07.012"},{"key":"e_1_2_12_5_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamadermatol.2024.0594"},{"key":"e_1_2_12_6_1","doi-asserted-by":"publisher","DOI":"10.2147\/JAA.S317009"},{"key":"e_1_2_12_7_1","doi-asserted-by":"publisher","DOI":"10.1097\/DER.0000000000000617"},{"key":"e_1_2_12_8_1","volume-title":"Social determinants of health: the solid facts","author":"Wilkinson 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