{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,7]],"date-time":"2026-08-07T15:33:42Z","timestamp":1786116822467,"version":"build-2736575974"},"reference-count":30,"publisher":"Wiley","license":[{"start":{"date-parts":[[2026,7,7]],"date-time":"2026-07-07T00:00:00Z","timestamp":1783382400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2026,7,7]],"date-time":"2026-07-07T00:00:00Z","timestamp":1783382400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100022606","name":"Almirall","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100022606","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acad Dermatol Venereol"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Nummular eczema (NE) is a chronic inflammatory skin disease characterized by intense pruritus, which can lead to sleep disturbance, reduced quality of life, and psychological distress. Despite its substantial burden on patients, there are currently no established clinical guidelines to support its diagnosis and management.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>This study aimed to develop the first expert consensus\u2010based recommendations for the definition, diagnosis, patient assessment and treatment of NE.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A Scientific Committee (SC) developed 64 statements across four domains\u2014definition, diagnosis, patient assessment and treatment\u2014based on a literature review and their own clinical expertise. A total of 63 experts (60 dermatologists and three specialist nurses) from 16 countries evaluated the statements via a two\u2010round modified Delphi. Consensus was defined statistically, and statements reaching agreement informed the development of practical, evidence\u2010informed clinical recommendations.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Of 64 statements, 49 (76.6%) achieved consensus: 5 of 7 on the definition, 11 of 18 on diagnosis, 15 of 18 on patient assessment and 18 of 21 on treatment. Recommendations emphasize clinical diagnosis and long\u2010term, individualized management; endorsed treatments include high\u2010potency topical corticosteroids, calcineurin inhibitors, topical JAK inhibitors, phototherapy and\u2014off\u2010label in most settings\u2014selected systemic agents for refractory disease. The recommendations also highlight critical gaps, notably the need to develop and validate NE tailored patient assessment tools and to conduct large, well\u2010designed clinical trials to establish the efficacy and safety of systemic therapies for NE, as well as defining specific treatment response targets.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>These are the first expert consensus recommendations to provide a comprehensive framework for the diagnosis and management of NE in clinical practice. They offer practical, evidence\u2010informed guidance to improve care for this underappreciated condition. Priority gaps include validated NE\u2010specific assessment tools and randomized trials of systemic therapies.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jdv.70560","type":"journal-article","created":{"date-parts":[[2026,7,7]],"date-time":"2026-07-07T12:51:48Z","timestamp":1783428708000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["European consensus recommendations for nummular eczema: A modified Delphi study"],"prefix":"10.1111","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0593-9925","authenticated-orcid":false,"given":"Mette","family":"Deleuran","sequence":"first","affiliation":[{"name":"Department of Dermatology Aarhus University Hospital  Aarhus Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0094-2674","authenticated-orcid":false,"given":"Kilian","family":"Eyerich","sequence":"additional","affiliation":[{"name":"Department of Dermatology and Venerology, Medical Center University of Freiburg  Freiburg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marjolein","family":"de Bruin\u2010Weller","sequence":"additional","affiliation":[{"name":"Department of Dermatology\/Allergology University Medical Center Utrecht  Utrecht the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pedro","family":"Herranz\u2010Pinto","sequence":"additional","affiliation":[{"name":"Department of Dermatology, La Paz University Hospital Autonomous University of Madrid  Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Silvia","family":"Ferrucci","sequence":"additional","affiliation":[{"name":"Dermatology Unit Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico of Milan  Milan Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephan","family":"Weidinger","sequence":"additional","affiliation":[{"name":"Department of Dermatology and Allergy University Medical Center Schleswig\u2010Holstein  Kiel Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"the NEED panel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,7,7]]},"reference":[{"key":"e_1_2_14_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mcna.2021.04.003"},{"key":"e_1_2_14_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2023.04.009"},{"key":"e_1_2_14_4_1","volume-title":"StatPearls","author":"Robinson 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