{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,21]],"date-time":"2026-07-21T09:02:17Z","timestamp":1784624537125,"version":"3.55.0"},"reference-count":92,"publisher":"Wiley","license":[{"start":{"date-parts":[[2026,7,21]],"date-time":"2026-07-21T00:00:00Z","timestamp":1784592000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,7,21]],"date-time":"2026-07-21T00:00:00Z","timestamp":1784592000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acad Dermatol Venereol"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Occupational eyelid dermatitis (ED) is a much\u2010neglected issue in public health, with important ramifications for patients' quality of life, employment and facial aesthetics. Patients with occupational ED are often younger, male and with an atopic background compared with those with non\u2010occupational ED. Common contact allergens include rubber additives, acrylates, isothiazolinones, fragrances, epoxy resins, potassium dichromate, colophonium, metals and topical medications. Contact allergens and irritants may cause occupational ED by direct or indirect exposure, for example, through transfer by hands, airborne exposure or connubial contact. At\u2010risk occupations include healthcare workers, hairdressers, industrial workers, electricians, cleaning staff, gardeners and florists as well as artists and craftsmen. The diagnostic work\u2010up should include medical and employment history and exposure analysis in addition to clinical manifestations according to Mathias' diagnostic criteria. Patch testing with standardized series as well as consideration of semi\u2010open or use tests with the patient's own work\u2010related materials are essential. The differential diagnosis requires a multidisciplinary approach to exclude ED of other aetiologies. Occupational ED is an important issue in public health meriting better reporting, medical surveillance and public health policies to ensure the safety and well\u2010being of the employees.<\/jats:p>","DOI":"10.1111\/jdv.70617","type":"journal-article","created":{"date-parts":[[2026,7,21]],"date-time":"2026-07-21T08:14:31Z","timestamp":1784621671000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Occupational eyelid dermatitis: A public health perspective"],"prefix":"10.1111","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1587-9137","authenticated-orcid":false,"given":"Elena","family":"Borzova","sequence":"first","affiliation":[{"name":"Dermatology Division, Graduate School of Medical and Dental Sciences Niigata University  Niigata Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"An","family":"Goossens","sequence":"additional","affiliation":[{"name":"Faculty of Medicine University KU Leuven  Leuven Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3423-5038","authenticated-orcid":false,"given":"Enzo","family":"Berardesca","sequence":"additional","affiliation":[{"name":"Philip Frost Department of Dermatology, Miller School of Medicine University of Miami  Miami Florida USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rosemary","family":"Nixon","sequence":"additional","affiliation":[{"name":"Occupational Dermatology Research and Education Centre Skin Health Institute  Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Steffen","family":"Heegaard","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology University of Copenhagen  Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4034-0985","authenticated-orcid":false,"given":"Elke O.","family":"Kreps","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology Ghent University Hospital  Ghent Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vanessa","family":"Smith","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine Ghent University  Ghent Belgium"},{"name":"Department of Rheumatology Ghent University Hospital  Ghent Belgium"},{"name":"Unit for Molecular Immunology and Inflammation VIB Inflammation Research Center (IRC)  Ghent Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maurizio","family":"Cutolo","sequence":"additional","affiliation":[{"name":"Laboratory of Experimental Rheumatology and Division of Clinical Rheumatology, Department of Internal Medicine University of Genova  Genova Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephanie M.","family":"Willerth","sequence":"additional","affiliation":[{"name":"Nanotherapeutics Cluster University of Victoria  Victoria Canada"},{"name":"Department of Mechanical Engineering and Division of Medical Sciences University of Victoria  Victoria Canada"},{"name":"School of Biomedical Engineering University of British Columbia  Vancouver Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6927-5956","authenticated-orcid":false,"given":"Emanuela","family":"Corsini","sequence":"additional","affiliation":[{"name":"Laboratory of Toxicology, Department of Pharmacological and Biomolecular Sciences \u2018Rodolfo Paoletti\u2019 Universit\u00e0 degli Studi di Milano  Milan Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3103-740X","authenticated-orcid":false,"given":"Erika","family":"Ponzini","sequence":"additional","affiliation":[{"name":"Department of Materials Science University of Milano\u2010Bicocca  Milan Italy"},{"name":"COMiB Research Center University of Milano\u2010Bicocca  Milan Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0706-6534","authenticated-orcid":false,"given":"Christopher J.","family":"Corrigan","sequence":"additional","affiliation":[{"name":"School of Immunology &amp; Microbial Science King's College London  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0928-8608","authenticated-orcid":false,"given":"Alain","family":"Ta\u00efeb","sequence":"additional","affiliation":[{"name":"INSERM U1312 University of Bordeaux  Bordeaux France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Werner","family":"Aberer","sequence":"additional","affiliation":[{"name":"Department of Dermatology Medical University of Graz  Graz Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7582-8609","authenticated-orcid":false,"given":"Riichiro","family":"Abe","sequence":"additional","affiliation":[{"name":"Dermatology Division, Graduate School of Medical and Dental Sciences Niigata University  Niigata Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Howard I.","family":"Maibach","sequence":"additional","affiliation":[{"name":"Department of Dermatology UCSF School of Medicine  San Francisco California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3770-1743","authenticated-orcid":false,"given":"Jacob P.","family":"Thyssen","sequence":"additional","affiliation":[{"name":"Department of Dermatology and Venereology, Biespebjerg Hospital University of Copenhagen  Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,7,21]]},"reference":[{"issue":"6","key":"e_1_2_18_2_1","doi-asserted-by":"crossref","first-page":"1118","DOI":"10.1016\/S0161-6420(94)31212-7","article-title":"Vascular anatomy of the eyelids","volume":"101","author":"Tucker SM","year":"1994","journal-title":"Ophthalmology"},{"issue":"1","key":"e_1_2_18_3_1","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1055\/s-2000-6831","article-title":"Abnormalities of eyelid position and function","volume":"20","author":"Martin TJ","year":"2000","journal-title":"Semin Neurol"},{"issue":"2","key":"e_1_2_18_4_1","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1111\/j.1600-0846.2007.00183.x","article-title":"Functional analyses of the eyelid skin constituting the most soft and smooth area of the face: contribution of its remarkably large superficial corneocytes to effective water\u2010holding capacity of the stratum corneum","volume":"13","author":"Pratchyapruit W","year":"2007","journal-title":"Skin Res Technol"},{"issue":"4","key":"e_1_2_18_5_1","doi-asserted-by":"crossref","first-page":"741","DOI":"10.1111\/bjd.14217","article-title":"Biology of the eyelash hair follicle: an enigma in plain sight","volume":"174","author":"Paus R","year":"2016","journal-title":"Br J Dermatol"},{"key":"e_1_2_18_6_1","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1016\/bs.acc.2024.03.002","article-title":"Tear biomarkers","volume":"120","author":"Ponzini E","year":"2024","journal-title":"Adv Clin Chem"},{"issue":"2","key":"e_1_2_18_7_1","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1038\/eye.1988.30","article-title":"Eyelid secretions and the prevention and production of disease","volume":"2","author":"Bron AJ","year":"1988","journal-title":"Eye"},{"issue":"8","key":"e_1_2_18_8_1","doi-asserted-by":"crossref","first-page":"802","DOI":"10.1111\/ceo.12321","article-title":"Demonstration of CD1a\u2010positive and zinc iodide\u2010osmium\u2010positive Langerhans cells in the human eyelid","volume":"42","author":"Rabi S","year":"2014","journal-title":"Clin Experiment Ophthalmol"},{"issue":"5","key":"e_1_2_18_9_1","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1136\/bjo.81.5.402","article-title":"Increased number of IgE positive Langerhans cells in the conjunctiva of patients with atopic dermatitis","volume":"81","author":"Yoshida A","year":"1997","journal-title":"Br J Ophthalmol"},{"issue":"4","key":"e_1_2_18_10_1","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1111\/cod.12616","article-title":"Occupational skin disease among Australian healthcare workers: a retrospective analysis from an occupational dermatology clinic, 1993\u20102014","volume":"75","author":"Higgins CL","year":"2016","journal-title":"Contact Derm"},{"issue":"3","key":"e_1_2_18_11_1","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1111\/cod.13040","article-title":"Is a specific eyelid patch test series useful? 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