{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T07:59:50Z","timestamp":1790323190535,"version":"4.1.0"},"reference-count":27,"publisher":"Wiley","license":[{"start":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T00:00:00Z","timestamp":1790294400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T00:00:00Z","timestamp":1790294400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acad Dermatol Venereol"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>\n                      <jats:italic>Trichophyton indotineae<\/jats:italic>\n                      (\n                      <jats:italic>T. mentagrophytes<\/jats:italic>\n                      genotype VIII) is spreading globally and is often terbinafine resistant. Guidance for diagnosis and treatment remains inconsistent.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We performed a four\u2010round modified Delphi study. A steering group developed a literature\u2010informed, 42\u2010item questionnaire on diagnosis and management. Consensus was predefined as \u226570% agreement.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Thirty\u2010four experts were invited; 20 completed rounds 1 and 2 and 19 completed rounds 3 and 4. Consensus was achieved for 34\/42 items (80.95%). The panel advised suspecting\n                      <jats:italic>T. indotineae<\/jats:italic>\n                      infection in patients with extensive or terbinafine\u2010recalcitrant dermatophytosis, particularly those with a history of travel to or residence in endemic regions. For diagnosis, the panel recommended KOH direct microscopy and fungal culture for suspected dermatophyte infection, and PCR (polymerase chain reaction) with species\u2010level discrimination or ITS sequencing for confirmation of\n                      <jats:italic>T. indotineae<\/jats:italic>\n                      . For resistance assessment, SQLE sequencing and antifungal susceptibility testing were preferred where available, particularly after treatment failure. For treating superficial fungal infections caused by\n                      <jats:italic>T. indotineae<\/jats:italic>\n                      , experts recommended oral itraconazole therapy (100\u2013200\u2009mg\/day for 6\u20138\u2009weeks, or longer as clinically indicated), with luliconazole 1% cream as the preferred adjunctive topical option. Oral posaconazole (300\u2009mg\/day for 4\u201312\u2009weeks) can be considered as the salvage therapy following itraconazole failure, keeping in mind antifungal stewardship.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>These consensus statements provide practical interim recommendations. Randomized controlled trials are needed to validate outcomes and optimize regimens.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jdv.70731","type":"journal-article","created":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T07:10:57Z","timestamp":1790320257000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Consensus recommendations for\n                    <i>Trichophyton indotineae<\/i>\n                    : A modified Delphi study"],"prefix":"10.1111","author":[{"given":"Aditya K.","family":"Gupta","sequence":"first","affiliation":[{"name":"Division of Dermatology, Department of Medicine, Temerty Faculty of Medicine University of Toronto  Toronto ON Canada"},{"name":"Division of Dermatology, Women's College Hospital  Toronto Ontario Canada"},{"name":"Mediprobe Research Inc.  London ON Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0691-640X","authenticated-orcid":false,"given":"Mesbah","family":"Talukder","sequence":"additional","affiliation":[{"name":"Mediprobe Research Inc.  London ON Canada"},{"name":"School of Pharmacy BRAC University  Dhaka Bangladesh"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7953-1047","authenticated-orcid":false,"given":"Ditte Marie L.","family":"Saunte","sequence":"additional","affiliation":[{"name":"PHOENIX Research Center, Department of Dermatology and Allergy Copenhagen University Hospital \u2010 Herlev and Gentofte  Hellerup Denmark"},{"name":"Department of Clinical Medicine, Faculty of Health and Medical Sciences University of Copenhagen  Copenhagen Denmark"},{"name":"Unit of Mycology, Department of Bacteria, Parasites and Fungi, Statens Serum Institut  Copenhagen Denmark"},{"name":"The European Academy of Dermatology and Venerology's Mycology Task Force  Lugano Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roderick James","family":"Hay","sequence":"additional","affiliation":[{"name":"The European Academy of Dermatology and Venerology's Mycology Task Force  Lugano Switzerland"},{"name":"St. Johns Institute of Dermatology Kings College London  London United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Arabatzis","sequence":"additional","affiliation":[{"name":"The European Academy of Dermatology and Venerology's Mycology Task Force  Lugano Switzerland"},{"name":"First Department of Dermatology and Venereology, School of Medicine Aristotle University  Thessaloniki Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3864-9174","authenticated-orcid":false,"given":"Avrom S.","family":"Caplan","sequence":"additional","affiliation":[{"name":"The Ronald O. Perelman Department of Dermatology NYU Grossman School of Medicine  New York New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eran","family":"Galili","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Sheba Medical Center  Ramat\u2010Gan Israel"},{"name":"Gray Faculty of Medical &amp; Health Sciences Tel Aviv University  Tel Aviv Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9957-1441","authenticated-orcid":false,"given":"Eckart","family":"Haneke","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Inselspital Bern University Hospital  Bern Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matilde","family":"Iorizzo","sequence":"additional","affiliation":[{"name":"Private Dermatology Practice  Bellinzona\/Lugano Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2964-7417","authenticated-orcid":false,"given":"Riad","family":"Kassem","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Sheba Medical Center  Ramat\u2010Gan Israel"},{"name":"Gray Faculty of Medical &amp; Health Sciences Tel Aviv University  Tel Aviv Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7020-7777","authenticated-orcid":false,"given":"Ananta","family":"Khurana","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Venereology and Leprosy Atal Bihari Vajpayee Institute of Medical Sciences and Dr Ram Manohar Lohia Hospital  New Delhi India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5913-9304","authenticated-orcid":false,"given":"Shari R.","family":"Lipner","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Weill Cornell Medicine  New York New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4899-7140","authenticated-orcid":false,"given":"Anna","family":"Lyakhovitsky","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Sheba Medical Center  Ramat\u2010Gan Israel"},{"name":"Gray Faculty of Medical &amp; Health Sciences Tel Aviv University  Tel Aviv Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brian W.","family":"Morrison","sequence":"additional","affiliation":[{"name":"Dr. Phillip Frost Department of Dermatology and Cutaneous Surgery University of Miami  Miller School of Medicine Miami FL USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vincent","family":"Piguet","sequence":"additional","affiliation":[{"name":"Division of Dermatology, Department of Medicine, Temerty Faculty of Medicine University of Toronto  Toronto ON Canada"},{"name":"Division of Dermatology, Women's College Hospital  Toronto Ontario Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bianca Maria","family":"Piraccini","sequence":"additional","affiliation":[{"name":"Piraccini Medical Center  Bologna Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9939-0771","authenticated-orcid":false,"given":"Carmen","family":"Rodr\u00edguez\u2010Cerdeira","sequence":"additional","affiliation":[{"name":"Fundaci\u00f3n Vithas, Grupo Hospitalario Vithas  Madrid Spain"},{"name":"Dermatology Department, Grupo Hospitalario (CMQ Concheiro), Vigo  Spain"},{"name":"Department of Health Sciences, Campus of Vigo University of Vigo  Vigo Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Avner","family":"Shemer","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Sheba Medical Center  Ramat\u2010Gan Israel"},{"name":"Gray Faculty of Medical &amp; Health Sciences Tel Aviv 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Frost Department of Dermatology and Cutaneous Surgery University of Miami  Miller School of Medicine Miami FL USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,9,25]]},"reference":[{"key":"e_1_2_15_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.20270"},{"key":"e_1_2_15_3_1","doi-asserted-by":"publisher","DOI":"10.3390\/jof8070757"},{"key":"e_1_2_15_4_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1010795"},{"key":"e_1_2_15_5_1","doi-asserted-by":"crossref","DOI":"10.1128\/jcm.00562-23","article-title":"Terbinafine\u2010resistant dermatophytes and the presence of Trichophyton indotineae in North America","volume":"61","author":"Canete\u2010Gibas CF","year":"2023","journal-title":"J Clin Microbiol"},{"key":"e_1_2_15_6_1","doi-asserted-by":"crossref","first-page":"192","DOI":"10.3201\/eid3101.240923","article-title":"Spread of antifungal\u2010resistant Trichophyton indotineae, United Kingdom, 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