{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T13:59:57Z","timestamp":1790258397772,"version":"4.1.0"},"reference-count":54,"publisher":"Wiley","license":[{"start":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T00:00:00Z","timestamp":1790208000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T00:00:00Z","timestamp":1790208000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acad Dermatol Venereol"],"abstract":"Abstract<\/jats:title>\n \n Background<\/jats:title>\n Diet has been implicated in acne pathogenesis, but evidence in adults remains limited, particularly regarding overall diet quality and potential sex differences.<\/jats:p>\n <\/jats:sec>\n \n Objectives<\/jats:title>\n To examine associations between diet quality and adult acne in UK Biobank and explore whether these associations differed by sex.<\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n In this cross sectional study, UK Biobank participants aged 37\u201373\u2009years at recruitment were classified as having current acne, a history of acne or no acne using self\u2010report and linked health records (ICD\u201010: L70). Dietary intake was assessed using food frequency questionnaires and repeated 24\u2010h recalls. Multivariable logistic regression examined associations between dietary quality indices and current acne, with secondary analyses of food groups and dairy products. Exploratory sex\u2010stratified analyses assessed effect modification.<\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n Among 228,757 participants, 1603 (0.7%) had current acne and 5709 (2.5%) reported a history of acne. Participants with acne were younger and more frequently female. Higher adherence to a Mediterranean\u2010style diet was associated with lower odds of current acne (per score: adjusted odds ratio [aOR] 0.93, 95% CI 0.87\u20130.99;\n p<\/jats:italic>\n \u2009=\u20090.021). In exploratory sex\u2010stratified analyses, this association was observed in women (aOR 0.90, 95% CI 0.83\u20130.97;\n p<\/jats:italic>\n \u2009=\u20090.007), whereas low\u2010carbohydrate dietary pattern scores were associated with higher odds in men (aOR 1.04, 95% CI 1.01\u20131.08;\n p<\/jats:italic>\n \u2009=\u20090.018). Cooked vegetables and yoghurt were inversely associated with acne, whereas pork, skimmed milk and milk\u2010based desserts showed positive associations.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusions<\/jats:title>\n Diet quality was modestly associated with adult acne in this UK middle\u2010aged and older population, with exploratory evidence of sex differences. Given the cross sectional design, modest effect sizes and possible diagnostic misclassification with rosacea in routine healthcare records, these findings should be interpreted cautiously. Prospective and interventional studies with detailed dermatological phenotyping are needed to establish causality and clinical relevance.<\/jats:p>\n <\/jats:sec>","DOI":"10.1111\/jdv.70747","type":"journal-article","created":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T13:07:32Z","timestamp":1790255252000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Associations between diet quality and adult acne: A cross sectional study in the\n UK<\/scp>\n Biobank"],"prefix":"10.1111","author":[{"ORCID":"https:\/\/orcid.org\/0009-0007-9939-4773","authenticated-orcid":false,"given":"Bochen","family":"Li","sequence":"first","affiliation":[{"name":"Department of Nutritional Sciences, School of Life Course & Population Sciences, Faculty of Life Sciences & Medicine King's College London London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yifan","family":"Xu","sequence":"additional","affiliation":[{"name":"Department of Nutritional Sciences, School of Life Course & Population Sciences, Faculty of Life Sciences & Medicine King's College London London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruotong","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Nutritional Sciences, School of Life Course & Population Sciences, Faculty of Life Sciences & Medicine King's College London London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alex","family":"Dregan","sequence":"additional","affiliation":[{"name":"Department of Psychological Medicine Institute of Psychiatry, Psychology and Neuroscience (IoPPN), King's College London London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rachel","family":"Gibson","sequence":"additional","affiliation":[{"name":"Department of Nutritional Sciences, School of Life Course & Population Sciences, Faculty of Life Sciences & Medicine King's College London London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thivi","family":"Maruthappu","sequence":"additional","affiliation":[{"name":"Department of Nutritional Sciences, School of Life Course & Population Sciences, Faculty of Life Sciences & Medicine King's College London London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5371-4427","authenticated-orcid":false,"given":"Christopher E. M.","family":"Griffiths","sequence":"additional","affiliation":[{"name":"Department of Dermatology King's College Hospital, King's College London London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1634-6930","authenticated-orcid":false,"given":"Wendy L.","family":"Hall","sequence":"additional","affiliation":[{"name":"Department of Nutritional Sciences, School of Life Course & Population Sciences, Faculty of Life Sciences & Medicine King's College London London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,9,24]]},"reference":[{"issue":"1","key":"e_1_2_14_2_1","first-page":"3","article-title":"A global perspective on the epidemiology of acne","volume":"172","author":"Tan JKL","year":"2015","journal-title":"Br J Dermatol"},{"issue":"1","key":"e_1_2_14_3_1","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1016\/j.jaad.2007.06.045","article-title":"The 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