{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,14]],"date-time":"2026-09-14T21:02:30Z","timestamp":1789419750442,"version":"build-2803163510"},"reference-count":35,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2017,4,26]],"date-time":"2017-04-26T00:00:00Z","timestamp":1493164800000},"content-version":"vor","delay-in-days":84,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Evidence Based Medicine"],"published-print":{"date-parts":[[2017,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background and aim<\/jats:title><jats:p>Esophageal variceal bleeding is a life\u2010threatening complication of liver cirrhosis. Upper gastrointestinal endoscopy was the gold standard for the diagnosis of esophageal varices (EVs). The study aimed to evaluate the accuracy of contrast\u2010enhanced computed tomography (CT) in the diagnosis of EVs and moderate\u2013severe EVs in patients with liver cirrhosis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Medical records in cirrhotic patients who were admitted to our hospital between June 2012 and June 2014 were retrospectively reviewed. Two observers reviewed the contrast\u2010enhanced CT scans to evaluate the presence and diameter of EVs. Area under curve (AUC), sensitivity, and specificity were calculated.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 52 cirrhotic patients were included in our study. According to the endoscopic results, 13.5% of these patients did not have any EVs, 11.5% had mild EVs, and 75% had moderate\u2013severe EVs. The AUC of contrast\u2010enhanced CT scans for the diagnosis of EVs was 0.835. The sensitivity and specificity were 95.56% and 71.43%, respectively. The AUC of contrast\u2010enhanced T scans for the diagnosis of moderate\u2013severe EVs was 0.821. When the cut\u2010off value for the diameter of EVs on contrast\u2010enhanced CT scans was 3.9 mm, the sensitivity and specificity were 89.74% and 69.23%, respectively.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Contrast\u2010enhanced CT scans had a moderate diagnostic accuracy for EVs in liver cirrhosis. It might be useful to decrease the use of upper gastrointestinal endoscopy in clinical practice.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jebm.12226","type":"journal-article","created":{"date-parts":[[2016,8,29]],"date-time":"2016-08-29T07:18:02Z","timestamp":1472455082000},"page":"46-52","source":"Crossref","is-referenced-by-count":25,"title":["Diagnostic accuracy of contrast\u2010enhanced computed tomography for esophageal varices in liver cirrhosis: a retrospective observational study"],"prefix":"10.1111","volume":"10","author":[{"given":"Han","family":"Deng","sequence":"first","affiliation":[{"name":"Liver Cirrhosis Study Group, Department of Gastroenterology General Hospital of Shenyang Military Area  Shenyang China"},{"name":"Postgraduate College Dalian Medical University  Dalian China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xingshun","family":"Qi","sequence":"additional","affiliation":[{"name":"Liver Cirrhosis Study Group, Department of Gastroenterology 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