{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,15]],"date-time":"2026-09-15T16:02:23Z","timestamp":1789488143647,"version":"build-2803163510"},"reference-count":30,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2026,1,4]],"date-time":"2026-01-04T00:00:00Z","timestamp":1767484800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,1,4]],"date-time":"2026-01-04T00:00:00Z","timestamp":1767484800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82330031"],"award-info":[{"award-number":["82330031"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Evidence Based Medicine"],"published-print":{"date-parts":[[2026,3]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To establish evidence\u2010based guidance to standardize the clinical application of artificial iris implantation in patients with iris defects.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A systematic literature search was performed following evidence\u2010based consensus development standards. Eighteen international experts participated in a Delphi process to define six core clinical issues. Evidence was screened, extracted, evaluated and integrated. Recommendations were formulated through iterative expert review.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>We established six key clinical issues related to artificial iris implantation and evidence\u2010based recommendations to address critical gaps in clinical practice. Key outcomes included standardized criteria for indications, contraindications, and type of artificial iris selection, key aspects of surgeon\u2013patient communication, surgical management principles and critical techniques, comprehensive perioperative care protocols, and strategies for managing long\u2010term postoperative complications associated with artificial iris implantation.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>This consensus standardizes artificial iris implantation through six evidence\u2010based recommendations. It provides a standardized protocol for safe clinical implementation to restore visual function and cosmetic integrity in patients with iris defect.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jebm.70101","type":"journal-article","created":{"date-parts":[[2026,1,4]],"date-time":"2026-01-04T10:13:37Z","timestamp":1767521617000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Expert Consensus on the Clinical Application of Artificial Iris"],"prefix":"10.1111","volume":"19","author":[{"given":"Hua","family":"Yan","sequence":"first","affiliation":[{"name":"Department of Ophthalmology Tianjin Medical University General Hospital  Tianjin China"},{"name":"Ministry of Education International Joint Laboratory of Ocular Diseases Tianjin Medical University General Hospital Tianjin China"},{"name":"Tianjin Key Laboratory of Ocular Trauma Tianjin Medical University General Hospital Tianjin 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