{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,10,2]],"date-time":"2023-10-02T06:11:07Z","timestamp":1696227067931},"reference-count":36,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2014,7,5]],"date-time":"2014-07-05T00:00:00Z","timestamp":1404518400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Evaluation Clinical Practice"],"published-print":{"date-parts":[[2014,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Rationale, aims and objectives<\/jats:title><jats:p>Declining capacity to function safely and independently in the community is a manifestation of ageing. Multiple measures are used to define and predict functional decline. This paper explores the use of partial least squares (<jats:styled-content style=\"fixed-case\">PLS<\/jats:styled-content>) analysis to understand the interaction between overtime measures of functional decline.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Comprehensive information was captured on individuals aged 65+ who presented at a large metropolitan Australian hospital Emergency Department (<jats:styled-content style=\"fixed-case\">ED<\/jats:styled-content>) for a complaint, which did not result in a hospital admission. They were followed\u2010up by telephone 1 and 3 months, post\u2010<jats:styled-content style=\"fixed-case\">ED<\/jats:styled-content> discharge. Information was collected each time on home situations (living alone, using community services, using a gait aid and having a formal carer), recent falls, hospitalizations and instrumental activities of daily living (<jats:styled-content style=\"fixed-case\">IADL<\/jats:styled-content>s). PLS analysis was applied to identify overtime relationships between measures.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Valid information was provided by 147 individuals at all three time points. The eight individual <jats:styled-content style=\"fixed-case\">IADL<\/jats:styled-content> items clustered clearly around physical, mental or combined mental and physical <jats:styled-content style=\"fixed-case\">IADL<\/jats:styled-content>s. These clusters were strongly related to increased use of community supports, gait aid and carer, and living alone. The relationship was less convincingly for hospitalizations, and falls were not explained well.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p><jats:styled-content style=\"fixed-case\">PLS<\/jats:styled-content> analysis offers a novel and comprehensive way of analysing complex health data, which allows sense to be made of relationships over a 3\u2010month period. This analysis provides a better understanding of declining function over time, than could be provided by current health modelling methods.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jep.12213","type":"journal-article","created":{"date-parts":[[2014,7,5]],"date-time":"2014-07-05T06:29:20Z","timestamp":1404541760000},"page":"1099-1105","source":"Crossref","is-referenced-by-count":0,"title":["Synthesizing complex data on functional decline in older people using partial least squares (<scp>PLS<\/scp>) analysis"],"prefix":"10.1111","volume":"20","author":[{"given":"Ellena Sophia A.","family":"King","sequence":"first","affiliation":[{"name":"International Centre for Allied Health Evidence (iCAHE) University of South Australia  Adelaide Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Karen A.","family":"Grimmer","sequence":"additional","affiliation":[{"name":"International Centre for Allied Health Evidence (iCAHE) University of South Australia  Adelaide Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alvin P.","family":"Atlas","sequence":"additional","affiliation":[{"name":"International Centre for Allied Health Evidence (iCAHE) University of South Australia  Adelaide Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Steve Francesco","family":"Milanese","sequence":"additional","affiliation":[{"name":"International Centre for Allied Health Evidence (iCAHE) University of South Australia  Adelaide Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2014,7,5]]},"reference":[{"key":"e_1_2_6_2_1","unstructured":"Federal Department of Health and Ageing(2013)Living longer living better: aged care reform in action. 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