{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,10]],"date-time":"2026-03-10T23:08:43Z","timestamp":1773184123794,"version":"3.50.1"},"reference-count":10,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2015,8,12]],"date-time":"2015-08-12T00:00:00Z","timestamp":1439337600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100000102","name":"Health Resources and Services Administration","doi-asserted-by":"crossref","id":[{"id":"10.13039\/100000102","id-type":"DOI","asserted-by":"crossref"}]},{"name":"Department of Health and Human Services","award":["#H46-MC24090"],"award-info":[{"award-number":["#H46-MC24090"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Evaluation Clinical Practice"],"published-print":{"date-parts":[[2015,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Rationale, aims and objectives<\/jats:title><jats:p>Evidence and consensus\u2010based guidelines for nutrition management of maple syrup urine disease (<jats:styled-content style=\"fixed-case\">MSUD<\/jats:styled-content>) were developed as part of a project to create nutrition guidelines for inherited metabolic disorders identified through newborn screening. The objective of this study was to describe and evaluate the role of evidence analysts in the systematic review phase of guideline development to improve quality of process and output and inform future guideline development projects.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Recruitment, training and output of evidence analysts were documented throughout the <jats:styled-content style=\"fixed-case\">MSUD<\/jats:styled-content> project. The role of analysts was to critically review and rate the scientific quality of published literature and abstract pertinent information using quality checklists and abstraction worksheets. A secure, web\u2010based application was developed to standardize the process and establish permanent documentation. Analysts completed a post\u2010project survey on perceptions of their role, training and the evidence analysis process.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Of 23 recruits, 65% (15) completed evidence analyst training; 73% of those (11) participated in the analysis of 98 literature articles. Analysts reviewed a median of four articles (range 1\u201316) with median productivity of 1.1 articles per month. All analysts surveyed (<jats:italic>n<\/jats:italic>\u2009=\u20099) understood their role and agreed that training was adequate; 100% agreed that analyst involvement was critical in developing guidelines for <jats:styled-content style=\"fixed-case\">MSUD<\/jats:styled-content>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Evidence analysts played a key role in appraising and abstracting evidence to develop nutrition guidelines for <jats:styled-content style=\"fixed-case\">MSUD<\/jats:styled-content>. With critical improvements to the process, particularly more stringent and systematic evaluation and documentation of analyst performance related to productivity and quality, we will continue to recruit, train and support evidence analysts in evidence\u2010based guideline development projects.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jep.12428","type":"journal-article","created":{"date-parts":[[2015,8,13]],"date-time":"2015-08-13T01:46:49Z","timestamp":1439430409000},"page":"1235-1243","source":"Crossref","is-referenced-by-count":2,"title":["The role of evidence analysts in creating nutrition management guidelines for inherited metabolic disorders"],"prefix":"10.1111","volume":"21","author":[{"given":"Yetsa","family":"Osara","sequence":"first","affiliation":[{"name":"Department of Human Genetics Emory University, School of Medicine  Atlanta GA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kathryn","family":"Coakley","sequence":"additional","affiliation":[{"name":"Nutrition and Health Sciences Graduate Division of Biological and Biomedical Sciences Emory University  Atlanta GA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alana","family":"Aisthorpe","sequence":"additional","affiliation":[{"name":"Department of Human Genetics Emory University, School of Medicine  Atlanta GA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adrya","family":"Stembridge","sequence":"additional","affiliation":[{"name":"Department of Human Genetics Emory University, School of Medicine  Atlanta GA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Meghan","family":"Quirk","sequence":"additional","affiliation":[{"name":"Center for Prevention Research Tennessee State University  Nashville TN USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Patricia L","family":"Splett","sequence":"additional","affiliation":[{"name":"Splett &amp; Associates  Stanchfield MN"},{"name":"Department of Food Science and Nutrition University of Minnesota  St. Paul MN USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fran","family":"Rohr","sequence":"additional","affiliation":[{"name":"Division of Genetics and Genomics Boston Children's Hospital  Boston MA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rani H.","family":"Singh","sequence":"additional","affiliation":[{"name":"Department of Human Genetics Emory University, School of Medicine  Atlanta GA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2015,8,12]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"crossref","first-page":"S296","DOI":"10.1542\/peds.2005-2633I","article-title":"Newborn screening: toward a uniform screening panel and system \u2013 executive summary","volume":"117","author":"American College of Medical Genetics Newborn Screening Expert Group","year":"2006","journal-title":"Pediatrics"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ymgme.2012.07.005"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ymgme.2013.05.008"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2753.2011.01807.x"},{"key":"e_1_2_9_6_1","volume-title":"Finding What Works in Health Care: Standards for Systematic Reviews","author":"Institute of Medicine (U.S.)","year":"2011"},{"key":"e_1_2_9_7_1","volume-title":"Evidence Analysis Manual: Steps in the Academy Evidence Analysis Process","author":"Academy of Nutrition and Dietetics","year":"2012"},{"key":"e_1_2_9_8_1","volume-title":"Nutrition Management Guidelines","author":"SERC\u2010GMDI","year":"2013"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ymgme.2014.05.006"},{"key":"e_1_2_9_10_1","volume-title":"Clinical Practice Guidelines We Can Trust","author":"Institute of Medicine (IOM)","year":"2011"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.3945\/ajcn.113.063776"}],"container-title":["Journal of Evaluation in Clinical Practice"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fjep.12428","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fjep.12428","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jep.12428","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,1]],"date-time":"2023-10-01T22:25:13Z","timestamp":1696199113000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/jep.12428"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,8,12]]},"references-count":10,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2015,12]]}},"alternative-id":["10.1111\/jep.12428"],"URL":"https:\/\/doi.org\/10.1111\/jep.12428","archive":["Portico"],"relation":{},"ISSN":["1356-1294","1365-2753"],"issn-type":[{"value":"1356-1294","type":"print"},{"value":"1365-2753","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,8,12]]}}}