{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,13]],"date-time":"2026-02-13T22:49:19Z","timestamp":1771022959699,"version":"3.50.1"},"reference-count":32,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2016,8,24]],"date-time":"2016-08-24T00:00:00Z","timestamp":1471996800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Evaluation Clinical Practice"],"published-print":{"date-parts":[[2017,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Older people with cancer are at increased risk of falling. Falls risk\u2013increasing drugs (FRIDs), comprising psychotropics and medications that cause orthostatic hypotension, are a potentially modifiable risk factor for falls. The objective of this study was to determine the prevalence and factors associated with use of FRIDs in older people with cancer. Patients aged \u226570\u00a0years who presented to a hospital outpatient clinic between January 2009 and July 2010 were included in the study. Information on current medication use, falls in previous 6\u00a0months, and frailty criteria was collected. Multinomial logistic regression was used to compute odds ratios (OR) and 95% confidence intervals (CIs) for factors associated with levels of FRID use. Overall, 76.1% (n\u00a0=\u00a0293) of 383 patients used FRIDs. This comprised psychotropics (31.2%, n\u00a0=\u00a0120) and medications causing orthostatic hypotension (69.9%, n\u00a0=\u00a0269). In total, 24.0% (n\u00a0=\u00a092) patients reported falling in the previous 6\u00a0months. Risk factors for falling were associated with use of psychotropics but not orthostatic hypotension drugs. Patients with a history of falls had increased odds of using psychotropics (\u22653 psychotropics; OR 13.50; 95%CI, 2.64\u201068.94). Likewise, frail patients had increased odds of using psychotropics (\u22653 psychotropics; OR 27.78; 95%CI, 6.06\u2010127.42). Risk factors for falling were associated with the use of psychotropics. This suggests that clinicians either do not recognize or underestimate the contribution of medications to falls in this high\u2010risk patient group. Further efforts are needed to rationalize medication regimens at the time of patients' first presentation to outpatient oncology services.<\/jats:p>","DOI":"10.1111\/jep.12624","type":"journal-article","created":{"date-parts":[[2016,8,24]],"date-time":"2016-08-24T07:02:43Z","timestamp":1472022163000},"page":"361-368","source":"Crossref","is-referenced-by-count":12,"title":["Factors associated with use of falls risk\u2013increasing drugs among patients of a geriatric oncology outpatient clinic in Australia: a cross\u2010sectional study"],"prefix":"10.1111","volume":"23","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0613-108X","authenticated-orcid":false,"given":"Justin P.","family":"Turner","sequence":"first","affiliation":[{"name":"Centre for Medicine Use and Safety, Faculty of Pharmacy and Pharmaceutical Sciences Monash University  Parkville Victoria Australia"},{"name":"School of Pharmacy and Medical Sciences University of South Australia  Adelaide South Australia Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hanna E.","family":"Tervonen","sequence":"additional","affiliation":[{"name":"School of Health Sciences, Centre for Population Health Research University of South Australia  Adelaide South Australia Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sepehr","family":"Shakib","sequence":"additional","affiliation":[{"name":"Department of Clinical Pharmacology Faculty of Health Science, University of Adelaide  Adelaide South Australia Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nimit","family":"Singhal","sequence":"additional","affiliation":[{"name":"Department of Medical Oncology Royal Adelaide Hospital  Adelaide South Australia Australia"},{"name":"Faculty of Medicine University of Adelaide  Adelaide South Australia Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert","family":"Prowse","sequence":"additional","affiliation":[{"name":"Department of Geriatric and Rehabilitation Medicine Royal Adelaide Hospital  Adelaide South Australia Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J. 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