{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,17]],"date-time":"2026-03-17T00:23:22Z","timestamp":1773707002795,"version":"3.50.1"},"reference-count":14,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2017,6,6]],"date-time":"2017-06-06T00:00:00Z","timestamp":1496707200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Evaluation Clinical Practice"],"published-print":{"date-parts":[[2017,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To determine whether hormonal treatments for frequent clinical cases (short stature, delayed and precocious puberty) are prescribed strictly according to clinical guidelines or based on personal tendencies, and whether the decisions correlate with physician's personal demographics (age, sex, and place of practice).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Cross\u2010sectional survey, with made\u2010up clinical cases, distributed to pediatric endocrinologists using 2 web\u2010based professional forums, Israeli and an international. The questionnaire included 8 clinical cases and 5 demographic questions regarding the physician. Differences in practice between Israeli and international endocrinologists were assessed, and correlation between the physician's gender and their decisions regarding treatment.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>One hundred fifty\u2010five physicians responded, 28% Israeli and 72% international. In girls with early puberty, 60% of international and 26% of Israeli physicians chose not to treat with a gonadotropin\u2010releasing hormone agonist. In girls with short stature, 79% of Israeli and 34% of international physicians offered growth hormone treatment. In girls with early puberty, both male and female physicians responded similarly in the international group, but in the Israeli group 47% of male and 15% of female doctors would not treat. In girls with constitutional growth delay, 67% of Israeli male doctors would not treat with growth hormone compared to 30% of Israeli female physicians.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Our study demonstrated significant practice differences between Israeli and international pediatric endocrinologists. Within the Israeli group, significant practice differences were seen between male and female physicians. Given that Israeli physicians follow the same clinical guidelines it is clear that a large \u201cgrey zone\u201d of clinical cases exist and much of the decisions on treatment are personal and influenced by personal beliefs or gender.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jep.12745","type":"journal-article","created":{"date-parts":[[2017,6,6]],"date-time":"2017-06-06T08:02:58Z","timestamp":1496736178000},"page":"866-869","source":"Crossref","is-referenced-by-count":4,"title":["\u201cReal\u2010world\u201d pediatric endocrine practice; how much is it influenced by physician's gender and region of practice. Results of an international survey"],"prefix":"10.1111","volume":"23","author":[{"given":"Keren","family":"Smuel","sequence":"first","affiliation":[{"name":"Pediatrics A The Edmond &amp; Lily Safra Children's Hospital, Sheba Medical Center  Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3864-9898","authenticated-orcid":false,"given":"Yonatan","family":"Yeshayahu","sequence":"additional","affiliation":[{"name":"Pediatrics A and Pediatric Endocrinology Division The Edmond &amp; Lily Safra Children's Hospital, Sheba Medical Center  Israel"},{"name":"School of Medicine Tel\u2010Aviv University  Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2017,6,6]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"crossref","DOI":"10.3238\/arztebl.2009.0295","volume-title":"Disorders of Pubertal Development","author":"Br\u00e4mswig J","year":"2009"},{"key":"e_1_2_5_3_1","article-title":"Recent advances in the understanding and management of delayed puberty","author":"Wei C","journal-title":"Arch Dis Child"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(95)70221-0"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2008-1783"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.17219\/acem\/31433"},{"issue":"2","key":"e_1_2_5_7_1","first-page":"415","article-title":"Unsustained or slowly progressive puberty in young girls: initial presentation and long\u2010term follow\u2010up of 20 untreated patients","volume":"84","author":"Palmert MR","year":"1999","journal-title":"J Clin Endocrinol Metab"},{"issue":"9","key":"e_1_2_5_8_1","doi-asserted-by":"crossref","first-page":"4127","DOI":"10.1210\/jcem.86.9.7852","article-title":"Sexual precocity in boys: accelerated versus slowly progressive puberty gonadotropin\u2010suppressive therapy and final height","volume":"86","author":"Lazar L","year":"2001","journal-title":"J Clin Endocrinol Metab"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1515\/jpem-2014-0003"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ghir.2007.11.003"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2009-3609"},{"issue":"3","key":"e_1_2_5_12_1","first-page":"343","article-title":"Nonmedical influences on medical decision making: an experimental technique using videotapes, factorial design, and survey sampling","volume":"32","author":"Feldman HA","year":"1997","journal-title":"Health Serv Res"},{"key":"e_1_2_5_13_1","doi-asserted-by":"publisher","DOI":"10.1097\/MLR.0b013e31819e1f04"},{"key":"e_1_2_5_14_1","doi-asserted-by":"publisher","DOI":"10.1159\/000316130"},{"key":"e_1_2_5_15_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12098-011-0607-6"}],"container-title":["Journal of Evaluation in Clinical Practice"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fjep.12745","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jep.12745","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,2]],"date-time":"2023-10-02T20:19:36Z","timestamp":1696277976000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/jep.12745"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,6,6]]},"references-count":14,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2017,8]]}},"alternative-id":["10.1111\/jep.12745"],"URL":"https:\/\/doi.org\/10.1111\/jep.12745","archive":["Portico"],"relation":{},"ISSN":["1356-1294","1365-2753"],"issn-type":[{"value":"1356-1294","type":"print"},{"value":"1365-2753","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,6,6]]}}}