{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T08:24:50Z","timestamp":1740126290610,"version":"3.37.3"},"reference-count":25,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2018,7,10]],"date-time":"2018-07-10T00:00:00Z","timestamp":1531180800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Evaluation Clinical Practice"],"published-print":{"date-parts":[[2018,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Rationale, aims, and objective<\/jats:title><jats:p>Contact tracing and screening is an essential strategy in tuberculosis (TB) control. Our aim is to assess factors associated with the degree of compliance with the main recommendations made to contacts of TB cases as part of the contact tracing programme, and to identify factors associated with non\u2010compliance.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We conducted a retrospective cohort study to assess the TB contact tracing programme at a Spanish hospital over the period 1998\u20102013.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total 2269 contacts were identified corresponding to 644 active TB index cases, and initial screening indicated that 3.2% had active TB and 41.3% had latent TB infection (LTBI). Compliance with the recommendation for primary chemoprophylaxis increased significantly over the study period, rising from 76.5% in the period 1998 to 2002 to 82.7% in the period 2010 to 2013. A similar significant increase was also observed for latent tuberculosis infection treatment (46.1% in the first period to 68.0% in the latter period). Factors that were significantly associated with non\u2010compliance with the recommendations were: being of foreign origin, alcoholism, being recommended latent tuberculosis infection treatment, repeating the tuberculin skin test at 3\u00a0months, a smear\u2010positive index case, and an index case aged under 35\u00a0years old.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Although compliance levels have improved over the years, it remains necessary to adopt strategies that target contacts in groups identified as being at risk of non\u2010compliance.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jep.12973","type":"journal-article","created":{"date-parts":[[2018,7,10]],"date-time":"2018-07-10T08:46:31Z","timestamp":1531212391000},"page":"758-766","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Assessment of 16\u2010year retrospective cohort study of factors associated with non\u2010compliance with a tuberculosis contact tracing programme at a Spanish hospital"],"prefix":"10.1111","volume":"24","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5492-1137","authenticated-orcid":false,"given":"Patricia","family":"Garc\u00eda","sequence":"first","affiliation":[{"name":"Preventive Medicine Service University General Hospital of Alicante  Pintor Baeza 11 03010 Alicante Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jos\u00e9","family":"Sanchez","sequence":"additional","affiliation":[{"name":"Preventive Medicine Service University General Hospital of Alicante  Pintor Baeza 11 03010 Alicante Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Juan","family":"Mora","sequence":"additional","affiliation":[{"name":"Preventive Medicine Service University General Hospital of Alicante  Pintor Baeza 11 03010 Alicante Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elena","family":"Ronda","sequence":"additional","affiliation":[{"name":"Public Health Research Group University of Alicante  Carretera San Vicente del Raspeig s\/n 03690 Alicante Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2018,7,10]]},"reference":[{"key":"e_1_2_7_2_1","unstructured":"2017"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.5588\/ijtld.13.0486"},{"issue":"4","key":"e_1_2_7_4_1","first-page":"183","article-title":"Factors predicting new tuberculosis infections and tuberculin conversions in a contact tracing system","volume":"18","author":"Goris\u2010Pereiras A","year":"2008","journal-title":"Enferm Clin"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1157\/13065835"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.287.8.991"},{"issue":"6","key":"e_1_2_7_7_1","first-page":"281","article-title":"Study investigating infection in contacts of tuberculosis patients in a semi\u2010urban area","volume":"21","author":"Alseda M","year":"2003","journal-title":"Enferm Infecc Microbiol Clin"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.3122\/jabfm.2017.04.170070"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.00009114"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.5588\/ijtld.13.0688"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/cis029"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1157\/13070281"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.3122\/jabfm.2017.04.170070"},{"key":"e_1_2_7_14_1","first-page":"1","article-title":"Centers for Disease Control and Prevention (CDC) Guidelines for the investigation of contacts of persons with infectious tuberculosis: recommendations from the National Tuberculosis Controllers Association and CDC","volume":"54","author":"National Tuberculosis Controllers Association","year":"2005","journal-title":"MMWR Recomm Rep"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(08)70071-9"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1093\/qjmed\/hcs045"},{"key":"e_1_2_7_17_1","unstructured":"World Health Organization (WHO).Recommendations for investigating contacts of persons with infectious tuberculosis in low\u2010 and middle\u2010income countries. 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