{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T01:28:20Z","timestamp":1747186100894,"version":"3.40.5"},"reference-count":36,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2020,9,15]],"date-time":"2020-09-15T00:00:00Z","timestamp":1600128000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Evaluation Clinical Practice"],"published-print":{"date-parts":[[2021,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Rationale, aims, and objectives<\/jats:title><jats:p>The objective was to measure the quality of clinical practice for the management of cystitis in adult women in general practice by collaborating with quality circles and the regional centre for antibiotic counsel.<\/jats:p><\/jats:sec><jats:sec><jats:title>Method<\/jats:title><jats:p>This descriptive cross\u2010sectional study was performed in 2018 in Normandy, France. A questionnaire composed of clinical vignettes was used to evaluate practices of general practitioners (GPs) with regard to cystitis classified into four categories: simple, at risk of complication, recurrent, and caused by multidrug\u2010resistant bacteria. The 2017 French Infectious Diseases Society's guidelines were used as a reference.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 142 GPs participated in the study (45.5% of the solicited). Fosfomycin\u2010trometamol and pivmecillinam were cited as first\u2010line treatments for simple cystitis by 134 (94%) and 38 (27%) participants, respectively. For at risk of complication cystitis, the treatments cited were cefixime by 64 participants (45%), ofloxacin by 50 (35%), pivmecillinam by 49 (35%), fosfomycin\u2010trometamol by 38 (27%), nitrofurantoin by 36 (25%), and amoxicillin\u2010clavulanic acid by 28 (20%). Mean compliance rates were 85% for simple cystitis, 39% for at risk of complication cystitis, 60% for recurrent cystitis and 14% for cystitis caused by multidrug\u2010resistant bacteria. Two criteria had less than 10% of the compliant answers: comprehensive knowledge of cystitis complication risk factors (9%) and positivity thresholds of urine cultures (10%).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>In this study, diagnostic means, follow\u2010up testing, and simple cystitis treatment (with fosfomycin predominantly mentioned) were broadly compliant. The use of critical antibiotics was too frequent for at risk of complication cystitis. There may be a need to improve the knowledge of professionals on antibiotic resistance and appropriate antibiotic use.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jep.13464","type":"journal-article","created":{"date-parts":[[2020,9,27]],"date-time":"2020-09-27T09:13:57Z","timestamp":1601198037000},"page":"421-428","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["General practitioners' clinical practice on the management of cystitis in Normandy, France: A clinical vignettes\u2010based study"],"prefix":"10.1111","volume":"27","author":[{"given":"Claire","family":"Beaurain","sequence":"first","affiliation":[{"name":"Centre R\u00e9gional de Conseil en Antibioth\u00e9rapie NormAntibio  Caen\u2010Rouen France"},{"name":"Universit\u00e9 de Caen Normandie, Medical school  Caen France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4342-4391","authenticated-orcid":false,"given":"Pascal","family":"Thibon","sequence":"additional","affiliation":[{"name":"Centre R\u00e9gional de Conseil en Antibioth\u00e9rapie NormAntibio  Caen\u2010Rouen France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elise","family":"Fiaux","sequence":"additional","affiliation":[{"name":"Centre R\u00e9gional de Conseil en Antibioth\u00e9rapie NormAntibio  Caen\u2010Rouen France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emmanuel","family":"Piednoir","sequence":"additional","affiliation":[{"name":"Centre R\u00e9gional de Conseil en Antibioth\u00e9rapie NormAntibio  Caen\u2010Rouen France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Claude","family":"Magnani","sequence":"additional","affiliation":[{"name":"Union R\u00e9gionale des M\u00e9decins Lib\u00e9raux de Normandie  Caen France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fran\u00e7ois","family":"Caron","sequence":"additional","affiliation":[{"name":"Universit\u00e9 de Rouen Normandie, Medical school  Rouen France"},{"name":"CHU de Rouen, Service Maladies infectieuses et tropicales  Rouen France"},{"name":"Groupe de Recherche sur l'Adaptation Microbienne (GRAM 2.0) Universit\u00e9 de Normandie, UNIROUEN, UNICAEN, GRAM 2.0  Rouen France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Renaud","family":"Verdon","sequence":"additional","affiliation":[{"name":"Universit\u00e9 de Caen Normandie, Medical school  Caen France"},{"name":"CHU de Caen, Service Maladies infectieuses et tropicales  Caen France"},{"name":"Groupe de Recherche sur l'Adaptation Microbienne (GRAM 2.0) Universit\u00e9 de Normandie, UNICAEN, UNIROUEN, GRAM 2.0  Caen France"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2020,9,15]]},"reference":[{"key":"e_1_2_8_2_1","unstructured":"ECDC. 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