{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T01:28:26Z","timestamp":1747186106065,"version":"3.40.5"},"reference-count":43,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2020,10,20]],"date-time":"2020-10-20T00:00:00Z","timestamp":1603152000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Evaluation Clinical Practice"],"published-print":{"date-parts":[[2021,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title><jats:sc>Rationale, aims, and objectives<\/jats:sc><\/jats:title><jats:p>Our aim was to investigate verbal representations of intervention effect\u2010size, uncertainty of evidence, and possible intervention comparators in statements concerning effects of interventions in Finnish clinical practice guidelines.<\/jats:p><\/jats:sec><jats:sec><jats:title><jats:sc>Method<\/jats:sc><\/jats:title><jats:p>We selected 10 clinical practice guidelines on common diseases and risk factors published by The Finnish Medical Society Duodecim. All the statements that considered beneficial effects of interventions and that were graded with a level of evidence (levels A, high, to D, very low) were included in analyses. We assessed whether the statements verbally represented intervention effect\u2010size, uncertainty of evidence or a possible comparator, and the reported outcome.<\/jats:p><\/jats:sec><jats:sec><jats:title><jats:sc>Results<\/jats:sc><\/jats:title><jats:p>Of 385 statements, verbal representation of beneficial effect\u2010sizes occurred in 25 (6%) statements. Most (72%) statements indicated that intervention had a beneficial effect, but did not specify effect\u2010size. Less than half (42%) of the statements represented uncertainty verbally. Comparisons to placebo or no\u2010treatment were rare (3%) and 18% of the statements compared interventions to other treatments. Against instructions, a considerable part (35%) of statements with B\u2010level evidence did not represent uncertainty.<\/jats:p><\/jats:sec><jats:sec><jats:title><jats:sc>Conclusion<\/jats:sc><\/jats:title><jats:p>Communicating beneficial intervention effects, effect\u2010sizes, possible comparators, and uncertainty of evidence require much broader attention in the clinical practice guideline context.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jep.13499","type":"journal-article","created":{"date-parts":[[2020,10,21]],"date-time":"2020-10-21T04:15:51Z","timestamp":1603253751000},"page":"759-766","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Verbal communication of effect\u2010sizes, possible comparators, and uncertainty of evidence in the Finnish clinical practice guidelines: Omitting effect\u2010sizes and comparators without expressing much uncertainty"],"prefix":"10.1111","volume":"27","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9258-9355","authenticated-orcid":false,"given":"Eero","family":"Raittio","sequence":"first","affiliation":[{"name":"Institute of Dentistry University of Eastern Finland  Kuopio Finland"},{"name":"Oral Health Care City of Tampere  Tampere Finland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2571-5622","authenticated-orcid":false,"given":"Lauri","family":"Raittio","sequence":"additional","affiliation":[{"name":"The Faculty of Medicine and Health Technology Tampere University  Tampere Finland"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2020,10,20]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jclinepi.2010.04.026"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jclinepi.2019.10.014"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamainternmed.2014.6016"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamainternmed.2016.8254"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-319-64310-6_13"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1177\/0272989X10391469"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12160-008-9037-8"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1539-6053.2008.00033.x"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1098\/rsos.190876"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1177\/0272989X18818166"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1177\/2381468316665365"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13063-019-3960-9"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jclinepi.2015.12.007"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen-2016-014129"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/jep.13455"},{"key":"e_1_2_7_17_1","article-title":"Rheumatoid Arthritis","author":"Duodecim Finnish Medical Society","year":"2017","journal-title":"Current Care Guidelines"},{"key":"e_1_2_7_18_1","unstructured":"FirkeS.Janitor: simple tools for examining and cleaning dirty data. 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