{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,12]],"date-time":"2025-12-12T13:49:41Z","timestamp":1765547381034,"version":"3.41.2"},"reference-count":27,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2025,2,7]],"date-time":"2025-02-07T00:00:00Z","timestamp":1738886400000},"content-version":"vor","delay-in-days":6,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Evaluation Clinical Practice"],"published-print":{"date-parts":[[2025,2]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>The present study was conducted to determine the relationship between prolonged complaints of women who had COVID\u201019 infection and whose symptoms persisted and their vaccination status against COVID\u201019.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This prospective observational study consisted of three groups [The Unvaccinated Group (Control Group: 89), the BioNTech Vaccine Group (114 people), and the Sinovac Vaccine Group (84 people)]. In this study, which included 287 women, prolonged COVID\u201019 symptoms in their spouses were also questioned. Information was obtained from the participants in the form of questions and answers under outpatient clinical conditions 2 months after their recovery. Women between the ages of 18\u201345 who had regular menstrual periods in the last 6 months before the pandemic, those whose COVID\u201019 test was negative and those who received a single dose of vaccine in the vaccinated group were included in the study.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The rates of loss of taste and prolonged symptoms of high fever in Sinovac\u2010vaccinated participants were lower than in the other groups in the present study (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.05). A total of 40.5% of those who were vaccinated with Sinovac after COVID\u201019 had a menstrual cycle length of every 28\u201340 days, which was higher than the percentage of participants in other groups, and 40.5% of those in this group did not have menstrual pain. Additionally, the menstrual period length of 62.3% of the participants who received the BioNTech vaccine increased (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.05). This increase is higher than the participants in the other group.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The study indicated that certain prolonged symptoms of COVID\u201019 infection were less common among participants vaccinated with Sinovac. In this group, the menstrual cycle length increased, while menstrual pain decreased.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jep.70005","type":"journal-article","created":{"date-parts":[[2025,2,7]],"date-time":"2025-02-07T06:19:26Z","timestamp":1738909166000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Associations Between COVID\u201019 Vaccination Status and Persistent Symptoms: A Prospective Study of Reproductive\u2010Age Women"],"prefix":"10.1111","volume":"31","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2029-7281","authenticated-orcid":false,"given":"Ilkin Seda Can","family":"Caglayan","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynaecologist Faculty of Medicine Sivas Cumhuriyet University Sivas 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