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Following the \u20186S\u2019 model, 19 Chinese and international databases (BMJ Best Practice, WHO, Cochrane Library, etc.), guidelines and professional association websites were searched from their inception to March 2025, using keywords such as tuberculosis, TB, medication adherence and drug adherence. Clinical guidelines, systematic reviews and manuals were included. Four researchers independently assessed the quality of the literature using AGREE II, AMSTAR and the Johns Hopkins Nursing Evidence\u2010Based Practice Manual tools. Extracted evidence was classified, summarized and graded using the JBI Evidence\u2010Based Healthcare Center's evidence hierarchy system (2014).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Fourteen publications were included (five systematic reviews, six guidelines, three manuals), yielding 25 pieces of evidence across four dimensions: healthcare services, medication adherence supervision, adverse drug reaction management and patient social support. Key evidence included: Providing patient\u2010centred care (Level 1 evidence); delivering health education and counselling throughout treatment (Level 1); implementing directly observed therapy (DOT) and digital health technologies (Level 1); prioritizing adverse drug reaction management (Level 4); strengthening social support systems (Level 1).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>This study integrates a multidimensional intervention framework to systematize adherence management in adult TB patients. However, clinical implementation must consider regional resources, cultural differences and individual patient needs. Future research should focus on three priorities: (1) scaling digital technologies; (2) developing adverse reaction early\u2010warning systems; and (3) exploring cost\u2010effective interventions.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jep.70280","type":"journal-article","created":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T07:30:02Z","timestamp":1761550202000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Evidence\u2010Based Summary on Medication Adherence Management for Adult Tuberculosis Patients With Multi\u2010Dimensional Strategies and Practice Framework"],"prefix":"10.1111","volume":"31","author":[{"ORCID":"https:\/\/orcid.org\/0009-0003-0550-8401","authenticated-orcid":false,"given":"Fanghui","family":"Xie","sequence":"first","affiliation":[{"name":"Public Health Clinical Center of Chengdu Chengdu Sichuan China"},{"name":"Department of Tuberculosis Public Health Clinical 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