{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,27]],"date-time":"2026-03-27T07:25:08Z","timestamp":1774596308921,"version":"3.50.1"},"reference-count":51,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Evaluation Clinical Practice"],"published-print":{"date-parts":[[2026,3]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Palliative care (PC) and End\u2010of\u2010Life Care (EOLC) focus on improving the quality of life of patients with life\u2010threatening illnesses by addressing physical, psychosocial, and spiritual needs. Clinical practice guidelines (CPGs) are essential for standardising care and supporting evidence\u2010based clinical decision\u2010making to improve patient outcomes but despite their importance, the methodological quality, transparency, and overall trustworthiness of CPGs require systematic evaluation. Given the limited assessment of CPGs in these areas, this study aimed to assess the methodological quality and transparency of CPGs in PC and EOLC for adult patients using the AGREE\u2010II tool. Additionally, we evaluated the completeness of reporting using the RIGHT checklist.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We conducted a scoping review to map the existing clinical CPGs in PC and EOLC. A comprehensive search of MEDLINE, EMBASE, and multiple international guideline repositories was performed to identify relevant CPGs endorsed by professional organisations. Two reviewers independently screened, extracted data, and assessed the methodological quality and transparency using the AGREE II tool and the completeness of reporting using the RIGHT checklist. Discrepancies were resolved by consensus or a third reviewer. Descriptive analyses and inter\u2010rater agreement were calculated.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>A total of 6430 citations were identified and screened, resulting in the final inclusion of 23 CPGs. Over half (52.2%) focused exclusively on PC and were developed by governmental institutions. Based on AGREE\u2010II assessment, 60.9% were classified as \u2018Recommended\u2019, 30.4% as \u2018Recommended with modifications\u2019. The highest\u2010scoring domains were Scope and Purpose (89%) and Clarity of Presentation (83%), while Applicability scored lowest (25%). Among the CPGs, \u2018IETS 2016 (Institute for Technological Assessment in Health, Colombia)\u2019 had the highest overall quality score (mean 96%), while \u2018CHPCA 2013 (Canadian Hospice Palliative Care Association, Canada)\u2019 had the lowest (mean 22%). Interrater agreement was good to excellent across most AGREE II domains, with the highest agreement for editorial independence (ICC\u2009=\u20090.87; 95% CI: 0.71\u20130.94) and the lowest for stakeholder involvement (ICC\u2009=\u20090.61; 95% CI: 0.29\u20130.81).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Several CPGs in PC and EOLC demonstrated significant gaps in applicability and transparency. To enhance their relevance and impact in clinical practice, improvements are needed in addressing real\u2010world implementation challenges and providing clearer information on methodology, funding sources, and conflict of interest management.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jep.70392","type":"journal-article","created":{"date-parts":[[2026,3,8]],"date-time":"2026-03-08T23:42:01Z","timestamp":1773013321000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Transparency and Methodological Quality of Clinical Practice Guidelines in Palliative Care. Scoping Review"],"prefix":"10.1111","volume":"32","author":[{"ORCID":"https:\/\/orcid.org\/0009-0003-9083-688X","authenticated-orcid":false,"given":"Julio Cesar","family":"Torres\u2010Cuellar","sequence":"first","affiliation":[{"name":"Department of Anesthesiology Universidad del Cauca Popay\u00e1n Colombia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6646-441X","authenticated-orcid":false,"given":"Daniel Alejandro","family":"P\u00e9rez\u2010Mu\u00f1oz","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology Universidad del Cauca Popay\u00e1n Colombia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0751-8932","authenticated-orcid":false,"given":"Ivan D.","family":"Florez","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Universidad de Antioquia Medell\u00edn Colombia"},{"name":"School of Rehabilitation Science McMaster University Hamilton Ontario Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2028-8510","authenticated-orcid":false,"given":"Sam H.","family":"Ahmedzai","sequence":"additional","affiliation":[{"name":"Medical School University of Sheffield Sheffield UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5560-2258","authenticated-orcid":false,"given":"Esther","family":"de Vries","sequence":"additional","affiliation":[{"name":"Department of Clinical Epidemiology and Biostatistics Pontificia Universidad Javeriana Bogot\u00e1 Colombia"},{"name":"School of Nursing and Midwifery Queen's University Belfast Belfast UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9421-3717","authenticated-orcid":false,"given":"Jose A.","family":"Calvache","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology Universidad del Cauca Popay\u00e1n Colombia"},{"name":"Department of Anesthesiology Erasmus MC Rotterdam Rotterdam the Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2026,3,1]]},"reference":[{"key":"e_1_2_10_2_1","unstructured":"World Health Organization Palliative Care [Internet] https:\/\/www.who.int\/europe\/news-room\/fact-sheets\/item\/palliative-care."},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12904-023-01148-x"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1136\/qshc.2008.028043"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/jep.12097"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13012-015-0294-1"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/ecc.12441"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0025-7753(03)73754-3"},{"key":"e_1_2_10_9_1","unstructured":"National Collaborating Centre for Methods and Tools Appraisal of Guidelines for Research & Evaluation (AGREE) II Instrument | NCCMT [Internet] https:\/\/www.nccmt.ca\/knowledge-repositories\/search\/100."},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.7326\/M16-1565"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00520-019-05220-2"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1089\/jpm.2020.0311"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.prro.2018.02.009"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00066-009-2044-2"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.rmr.2017.03.017"},{"key":"e_1_2_10_16_1","first-page":"235","article-title":"Sedation in Palliative Care\u2014A Clinically Oriented Overview of Guidelines and Treatment Recommendations","volume":"120","author":"Klein C.","year":"2023","journal-title":"Deutsches A\u0308rzteblatt International"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1089\/jpm.2021.0646"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.n71"},{"key":"e_1_2_10_19_1","volume-title":"Clinical Practice Guidelines We Can Trust [Internet]","author":"Committee on Standards for Developing Trustworthy Clinical Practice Guidelines, Board on Health Care Services, Institute of Medicine","year":"2011"},{"key":"e_1_2_10_20_1","unstructured":"G.GoulasHow Can I Cite Covidence? 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