{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T13:58:16Z","timestamp":1785592696178,"version":"3.56.0"},"reference-count":43,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T00:00:00Z","timestamp":1777852800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T00:00:00Z","timestamp":1777852800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Evaluation Clinical Practice"],"published-print":{"date-parts":[[2026,6]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>Several clinical practice guidelines (CPGs) have been developed for complex regional pain syndrome (CRPS). The aim of our study was to appraise CPGs for non\u2010pharmacological conservative management of CRPS.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods<\/jats:title>\n                    <jats:p>We systematically searched five electronic databases, from inception to January 2025, to include CPGs that focused on non\u2010pharmacological conservative management of CRPS. We used AGREE\u2010II to evaluate the quality of the CPGs. Recommendations, aims, and treatment algorithms of the CPGs were presented in a narrative format, thematic analysis, and matrixes to summarise, categorise, and compare the findings of the guidelines.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Nine CPGs met the inclusion criteria, including three updated versions of previously published guidelines. After accounting for updates, six unique guidelines were appraised. Two were rated as high\u2010quality, two as moderate\u2010quality, and two as low\u2010quality. All CPGs scored &gt;\u200960% in the AGREE\u2010II domains of scope\/purpose and clarity of presentation, while rigour of development was the lowest\u2010scoring domain, with only two guidelines achieving \u2265\u200960%. No guideline addressed updating procedures. The most common interventions recommended by CPGs were pain management (100%) followed by functional restoration (83%), stress\u2010loading (67%), psychotherapy (67%), edema management (67%), gentle active movements (67%), vocational rehabilitation (67%), normal functional activities (67%), general PT interventions (67%), and isometric\u2010isotonic strengthening (67%).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The methodological quality of many CPGs for non\u2010pharmacological management of CRPS is low, particularly in the domain of rigour of development. Recommendations across guidelines are variable, often lacking detail, consistency, and integration of supporting evidence. Pain management, functional restoration, and inter\/multidisciplinary care were the most commonly recommended considerations, while guidance on treatment frequency, dosage, and implementation strategies was limited.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jep.70417","type":"journal-article","created":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T14:19:16Z","timestamp":1777904356000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["A Systematic Critical Appraisal of Clinical Practice Guidelines for Non\u2010Pharmacological \u200eConservative Management of Complex Regional Pain Syndrome (CRPS) Using the \u200eAGREE\u2010II Instrument"],"prefix":"10.1111","volume":"32","author":[{"given":"Erfan","family":"Shafiee","sequence":"first","affiliation":[{"name":"School of Physical Therapy University of Western Ontario London Ontario Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joy","family":"MacDermid","sequence":"additional","affiliation":[{"name":"School of Physical Therapy University of Western Ontario London Ontario Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tara","family":"Packham","sequence":"additional","affiliation":[{"name":"School of Rehabilitation Sciences McMaster University Hamilton Ontario Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruby","family":"Grewal","sequence":"additional","affiliation":[{"name":"Department of Surgery University of Western Ontario London Ontario Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Walton","sequence":"additional","affiliation":[{"name":"School of Physical Therapy University of Western Ontario London Ontario Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5470-5319","authenticated-orcid":false,"given":"Maryam","family":"Farzad","sequence":"additional","affiliation":[{"name":"School of Physical Therapy University of Western Ontario London Ontario Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,5,4]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/9781119701170.ch37"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40122-021-00279-4"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jclinane.2017.03.027"},{"issue":"2","key":"e_1_2_11_5_1","first-page":"257","article-title":"Prevalence of Specific Types of Pain Diagnoses in a Sample of United States Adults","volume":"20","author":"Murphy K. 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