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All injectable medications were included. Medication cost per millilitre was calculated using hospital procurement records. Syringe sizes were defined according to prescribed volumes. Syringe dead space was measured using an analytical balance (ATY224, Shimadzu, Japan), and wasted volumes and financial losses were estimated. The medication wastage rate was calculated as the ratio between wasted value and total medication expenditure.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>A total of 120 medications met the inclusion criteria, accounting for 693,933 prescriptions. The estimated wasted volume due to residual volume was 41,394.47\u2009mL. The top ten medications accounted for 51.72% of prescriptions and 48.18% of the wasted financial value. The overall hospital wastage rate was approximately 1.16%. Syringe dead space, frequency of medication administration, and cost per millilitre were identified as the main contributors to medication wastage.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Syringe dead space and residual volume constitute a measurable and avoidable source of medication loss, with relevant economic implications. These findings can inform procurement strategies, waste reduction interventions, and public health policies aimed at optimising healthcare resource use.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jep.70530","type":"journal-article","created":{"date-parts":[[2026,7,19]],"date-time":"2026-07-19T14:21:38Z","timestamp":1784470898000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Unexplored Factors in Medication Wastage: Investigating Economic Impact in a Brazilian Teaching Hospital"],"prefix":"10.1111","volume":"32","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9598-6276","authenticated-orcid":false,"given":"Yago Marcos","family":"Pessoa\u2010Gon\u00e7alves","sequence":"first","affiliation":[{"name":"Institute of Natural and Biological Sciences research building Prof. Alu\u00edzio Rosa Prata Universidade Federal do Tri\u00e2ngulo Mineiro. Immunology Laboratory and Bioinformatics Uberaba Minas Gerais Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-9578-1258","authenticated-orcid":false,"given":"Victor Hugo Palhares","family":"Fl\u00e1vio\u2010Reis","sequence":"additional","affiliation":[{"name":"Institute of Natural and Biological Sciences research building Prof. Alu\u00edzio Rosa Prata Universidade Federal do Tri\u00e2ngulo Mineiro. 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