{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T11:44:59Z","timestamp":1790077499492,"version":"4.0.1"},"reference-count":21,"publisher":"Wiley","issue":"S1","license":[{"start":{"date-parts":[[2014,10,24]],"date-time":"2014-10-24T00:00:00Z","timestamp":1414108800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Esthet Restor Dent"],"published-print":{"date-parts":[[2015,3]]},"abstract":"Abstract<\/jats:title>Objective<\/jats:title>To evaluate the facial profiles and functional recovery of 18 patients treated by a computer\u2010aided designed\/manufactured hollow obturator prosthesis (CAD<\/jats:styled-content>\/CAM<\/jats:styled-content> prosthesis) after total maxillectomy for malignant maxillary sinus tumor.<\/jats:p><\/jats:sec>Materials and Methods<\/jats:title>A retrospective observational study was performed to evaluate the facial profiles and functional recovery of 18 patients with T3\u20104a<\/jats:sub>N0<\/jats:sub>M0<\/jats:sub><\/jats:styled-content> maxillary sinus cancer, who were treated by total maxillectomy and simultaneous implantation of a computer\u2010aided designed\/manufactured hollow obturator prosthesis (CAD<\/jats:styled-content>\/CAM<\/jats:styled-content> prosthesis). Follow\u2010ups were performed 1, 3, 6, and 12 months after surgery. Facial measurements, speech intelligibility, and chewing and swallowing functions were examined. Thirteen patients converted to a permanent prosthesis 6 months after surgery. Comparisons were made between patients with and without the CAD<\/jats:styled-content>\/CAM<\/jats:styled-content> or permanent prosthesis at various times using SPSS<\/jats:styled-content>13.0 statistical software (SPSS Inc., Chicago, IL, USA).<\/jats:p><\/jats:sec>Results<\/jats:title>Speech intelligibility, facial depression, and eyeball prolapse results showed improvements with prosthesis use at 1, 3, and 6 months after surgery (p<\/jats:italic>\u2009<\u20090.05). Swallowing function improved from level V<\/jats:styled-content> to level II<\/jats:styled-content>\u2013IV<\/jats:styled-content> with prosthesis use at 1, 3, and 6 months, and reached level I<\/jats:styled-content> or II<\/jats:styled-content> with permanent prosthesis use at 12 months after surgery.<\/jats:p><\/jats:sec>Conclusions<\/jats:title>Simultaneous CAD<\/jats:styled-content>\/CAM<\/jats:styled-content> prosthesis implantation recovered the facial profile, enhanced the speaking, swallowing, and chewing functions, and improved the quality of life of patients. Tumor recurrence can be detected by direct observation of the postoperative maxillary cavity. Therefore, this operation is recommended for simultaneous excision repair and functional reconstruction after total maxillectomy.<\/jats:p><\/jats:sec>Clinical Significance<\/jats:title>This surgical treatment of maxillary sinus cancer is applied rarely in C<\/jats:styled-content>hina, but it has a good effect based on our observation. Simultaneous CAD<\/jats:styled-content>\/CAM<\/jats:styled-content> prosthesis implantation after total maxillectomy can recover the facial profile, enhance the speaking, swallowing, and chewing functions, and improve the quality of life of patients. Tumor recurrence can be detected by direct observation of the postoperative maxillary cavity. This technique avoids the need for dental implants because the bottom part of the prosthesis contains a palatal plate with dentures.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jerd.12117","type":"journal-article","created":{"date-parts":[[2014,10,24]],"date-time":"2014-10-24T16:22:23Z","timestamp":1414167743000},"source":"Crossref","is-referenced-by-count":17,"title":["Functional Evaluation of a CAD<\/scp>\/CAM<\/scp> Prosthesis for Immediate Defect Repair after Total Maxillectomy: A Case Series of 18 Patients with Maxillary Sinus Cancer"],"prefix":"10.1111","volume":"27","author":[{"given":"Fei\u2010Fei","family":"Jiang","sequence":"first","affiliation":[{"name":"Department of Otorhinolaryngology Head and Neck Surgery The First Hospital of China Medical University Shenyang 110001 Liaoning China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yan","family":"Hou","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology Head and Neck Surgery Affiliated Hospital of Inner Mongolia University for the Nationalities Tongliao 028007 Inner Mongolia China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Li","family":"Lu","sequence":"additional","affiliation":[{"name":"Department of Oral Maxillofacial Surgery Stomatology Hospital of China Medical University Shenyang 110002 Liaoning China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiao\u2010Xu","family":"Ding","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology Head and Neck Surgery The First Hospital of China Medical University Shenyang 110001 Liaoning China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology Head and Neck Surgery The First Hospital of China Medical University Shenyang 110001 Liaoning China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ai\u2010Hui","family":"Yan","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology Head and Neck Surgery The First Hospital of China Medical University Shenyang 110001 Liaoning China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2014,10,24]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1470-2045(06)70616-7"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/MOO.0b013e328304b426"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bjps.2008.06.084"},{"key":"e_1_2_7_5_1","first-page":"220","article-title":"Analysis of clinical efficacy of maxillofacial prosthesis for 10 patients with maxillary defects","volume":"3","author":"Bai B","year":"2010","journal-title":"Chin J Pract Stomatol"},{"key":"e_1_2_7_6_1","first-page":"464","article-title":"Maxillary obturator 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