{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T23:21:50Z","timestamp":1790637710119,"version":"4.1.0"},"reference-count":45,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2016,9,29]],"date-time":"2016-09-29T00:00:00Z","timestamp":1475107200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Esthet Restor Dent"],"published-print":{"date-parts":[[2017,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p>To evaluate the marginal and internal adaptation of CAD\/CAM lithium\u2010disilicate inlay restorations fabricated by two milling systems (Five and Three\u2010axis), and a traditional heat\u2010press technique.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Fifteen premolar teeth with an MOD cavity preparation were fabricated. Lithium\u2010disilicate inlay restorations were obtained by three fabrication techniques and fitted to their dies (<jats:italic>n<\/jats:italic>\u2009=\u200915\/gp) as follows: <jats:italic>Group\u20101<\/jats:italic>, three\u2010axis milling system, <jats:italic>Group\u20102<\/jats:italic>, five\u2010axis milling system, <jats:italic>Group\u20103<\/jats:italic>, conventional heat\u2010press technique. Gaps were evaluated by X\u2010ray microtomography. Marginal gap (MG), occlusal\u2010marginal gap (OMG), proximal\u2010marginal gap (PMG), gingival\u2010marginal gap (GMG), absolute marginal discrepancy (AMD), axial\u2010internal gap (AIG), and occlusal\u2010internal gap (OIG) were evaluated at 120 different points per inlay. Data were analyzed using repeated measures ANOVA. Pairwise comparisons were conducted for post\u2010hoc testes and the Bonferroni correction was used to adjust for multiple comparisons (<jats:italic>\u03b1<\/jats:italic>\u2009=\u20090.007).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The heat\u2010press group demonstrated significantly smaller mean\u2010values amongst all outcomes compared with CAD\/CAM groups except for GMG, where there was no statistically significant difference between groups in the ANOVA (<jats:italic>p<\/jats:italic>\u2009=\u20090.042). Within the CAD\/CAM groups, the five\u2010axis group showed significantly lower OMG mean\u2010value compared with the three\u2010axis group <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001, and lower AIG mean\u2010value compared with the three\u2010axis group <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001. There was no significant difference between the five\u2010axis and the three\u2010axis groups' AMD, MG, PMG, and OIG locations.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Different fabrication techniques affected the marginal and internal adaptation of ceramic inlay restorations. The heat\u2010press group showed the best marginal and internal adaptation results; however, in every group, all samples were within the clinically acceptable MG limit (100 \u03bcm).<\/jats:p><\/jats:sec><jats:sec><jats:title>Clinical Significance<\/jats:title><jats:p>The marginal fit and internal adaptation of inlay ceramic restorations fabricated by a five\u2010axis milling system have not been tested or compared with those fabricated by three\u2010axis machines and the conventional heat\u2010press method. The preferred method of inlay fabrication, whether in the lab or chair side, may be influenced by the results of this study and could affect future clinical decision\u2010making. (J Esthet Restor Dent 29:49\u201358, 2017)<\/jats:p><\/jats:sec>","DOI":"10.1111\/jerd.12271","type":"journal-article","created":{"date-parts":[[2016,9,29]],"date-time":"2016-09-29T15:18:03Z","timestamp":1475162283000},"page":"49-58","source":"Crossref","is-referenced-by-count":49,"title":["Micro\u2010CT Evaluation of Ceramic Inlays: Comparison of the Marginal and Internal Fit of Five and Three Axis CAM Systems with a Heat Press Technique"],"prefix":"10.1111","volume":"29","author":[{"given":"Norah K.","family":"Alajaji","sequence":"first","affiliation":[{"name":"Clinical Specialist, Department of Restorative Dentistry National Guard Hospital Riyadh Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Bardwell","sequence":"additional","affiliation":[{"name":"Clinical Professor, Prosthodontics and Operative Dentistry Tufts University School of Dental Medicine Boston MA 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