{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T21:41:10Z","timestamp":1789594870673,"version":"build-2803163510"},"reference-count":48,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2020,7,24]],"date-time":"2020-07-24T00:00:00Z","timestamp":1595548800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Esthet Restor Dent"],"published-print":{"date-parts":[[2020,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To assess the clinical efficacy and esthetic outcome of porcine\u2010derived dermal collagen matrix in comparison with connective tissue graft in the treatment of multiple adjacent gingival recessions (MAGR), 6 and 12\u2009months after the surgery.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and methods<\/jats:title><jats:p>Twenty patients with bilateral type I MAGR were treated randomly with porcine\u2010derived dermal collagen matrix (test site) or connective tissue graft (control site) in combination with a modified coronally advanced tunnel technique. The primary objectives were to evaluate the mean and complete root coverage. The secondary objectives were to assess keratinized tissue width, gingival thickness gain, and root coverage esthetic score.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Six and 12\u2009months postoperatively, both groups achieved significant improvements in all clinical parameters compared to baseline, with no statistically significant differences between the groups. Mean root coverage change (\u039412m \u2212 6 m) was statistically significant between the groups in favor of connective tissue graft, and twice as many patients exhibited a complete coverage of all recessions in the control group than the test group.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The porcine\u2010derived dermal collagen matrix combined with a modified coronally advanced tunnel technique resulted in satisfactory clinical and esthetic outcomes, which were similar to connective tissue graft.<\/jats:p><\/jats:sec><jats:sec><jats:title>Clinical significance<\/jats:title><jats:p>Porcine\u2010derived dermal collagen matrix (XDM) may be proposed as a substitute for connective tissue graft in multiple adjacent recession treatment due to successful root coverage, a significant increase of gingival thickness, and high esthetic outcomes. The clinical benefits for the use of XDM could be: (a) second surgical wound avoidance, (b) patient discomfort decrease, and (c) lower complications' rate.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jerd.12624","type":"journal-article","created":{"date-parts":[[2020,7,24]],"date-time":"2020-07-24T09:26:13Z","timestamp":1595582773000},"page":"681-690","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":34,"title":["The use of collagen porcine dermal matrix and connective tissue graft with modified coronally advanced tunnel technique in the treatment of multiple adjacent type I gingival recessions: A randomized, controlled clinical trial"],"prefix":"10.1111","volume":"32","author":[{"given":"Dragana L.","family":"Rakasevic","sequence":"first","affiliation":[{"name":"Department of Periodontology, School of Dental Medicine University of Belgrade  Belgrade Serbia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Iva Z.","family":"Milinkovic","sequence":"additional","affiliation":[{"name":"Department of Periodontology, School of Dental Medicine University of Belgrade  Belgrade Serbia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sasa M.","family":"Jankovic","sequence":"additional","affiliation":[{"name":"Department of Periodontology, School of Dental Medicine University of Belgrade  Belgrade Serbia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ivan A.","family":"Soldatovic","sequence":"additional","affiliation":[{"name":"Institute for Biostatistics University of Belgrade  Belgrade Serbia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zoran M.","family":"Aleksic","sequence":"additional","affiliation":[{"name":"Department of Periodontology, School of Dental Medicine University of Belgrade  Belgrade Serbia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8418-2395","authenticated-orcid":false,"given":"Natasa S.","family":"Nikolic\u2010Jakoba","sequence":"additional","affiliation":[{"name":"Department of Periodontology, School of Dental Medicine University of Belgrade  Belgrade Serbia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,7,24]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1902\/annals.2003.8.1.303"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/prd.12059"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcpe.12112"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2009.090122"},{"issue":"2","key":"e_1_2_7_6_1","first-page":"8","article-title":"A classification of marginal tissue recession","volume":"5","author":"Miller PD","year":"1985","journal-title":"Int J Periodontics Restor Dent"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.2008.01267.x"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2010.090540"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2015.130674"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.2009.01492.x"},{"issue":"7","key":"e_1_2_7_11_1","first-page":"545","article-title":"Predictability of surgical techniques used for coverage of multiple adjacent gingival recessions: a systematic review","volume":"43","author":"Hofmanner P","year":"2012","journal-title":"Quintessence Int"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcpe.12627"},{"issue":"1","key":"e_1_2_7_13_1","first-page":"17","article-title":"Treatment of multiple adjacent Miller class I and II gingival recessions with collagen matrix and the modified coronally advanced tunnel technique","volume":"44","author":"Molnar B","year":"2013","journal-title":"Quintessence Int"},{"issue":"2","key":"e_1_2_7_14_1","first-page":"S52","article-title":"Periodontal soft tissue root coverage procedures: a consensus report from the AAP Regeneration Workshop","volume":"86","author":"Tatakis DN","year":"2014","journal-title":"J Periodontol"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcpe.12172"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcpe.12477"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.11607\/prd.1998"},{"issue":"10","key":"e_1_2_7_18_1","first-page":"829","article-title":"The modified coronally advanced tunnel combined with an enamel matrix derivative and subepithelial connective tissue graft for the treatment of isolated mandibular Miller class I and II gingival recessions: a report of 16 cases","volume":"45","author":"Sculean A","year":"2014","journal-title":"Quintessence Int"},{"issue":"8","key":"e_1_2_7_19_1","first-page":"653","article-title":"Treatment of multiple adjacent maxillary Miller class I, II, and III gingival recessions with the modified coronally advanced tunnel, enamel matrix derivative, and subepithelial connective tissue graft: a report of 12 cases","volume":"47","author":"Sculean A","year":"2016","journal-title":"Quintessence Int"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2009.080253"},{"issue":"2","key":"e_1_2_7_21_1","first-page":"41","article-title":"Use of platelet\u2010rich fibrin membrane following treatment of gingival recession: a randomized clinical trial","volume":"32","author":"Jankovic S","year":"2012","journal-title":"Int J Periodontics Restor Dent"},{"issue":"2","key":"e_1_2_7_22_1","first-page":"S1","article-title":"Coverage of multiple recessions using the tunnel technique and a collagen matrix in the maxilla or mandible: a 6\u2010month study","volume":"32","author":"Cieslik\u2010Wegemund M","year":"2018","journal-title":"J Biol Regul Homeost Agents"},{"key":"e_1_2_7_23_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2016.150676"},{"key":"e_1_2_7_24_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00784-016-1757-8"},{"issue":"20","key":"e_1_2_7_25_1","first-page":"S199","article-title":"Mucogingival conditions in the natural dentition: narrative review, case definitions, and diagnostic considerations","volume":"45","author":"Cortellini P","year":"2018","journal-title":"J Clin Periodontol"},{"key":"e_1_2_7_26_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.1972.43.1.38"},{"key":"e_1_2_7_27_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcpe.12224"},{"issue":"6","key":"e_1_2_7_28_1","first-page":"573","article-title":"A technique to identify and reconstruct the cement\u2010enamel junction level using combined periodontal and restorative treatment of gingival recession. A prospective clinical study","volume":"30","author":"Cairo F","year":"2010","journal-title":"Int J Periodontics Restor Dent"},{"key":"e_1_2_7_29_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2009.090041"},{"key":"e_1_2_7_30_1","first-page":"105","article-title":"Effectiveness of benzydamyne HCl in the treatment of periodontal post\u2010surgical patients","volume":"10","author":"Landry RG","year":"1988","journal-title":"Res Clin Forums"},{"key":"e_1_2_7_31_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2009.080565"},{"issue":"3","key":"e_1_2_7_32_1","first-page":"279","article-title":"A single\u2010incision technique to harvest subepithelial connective tissue grafts from the palate","volume":"19","author":"Hurzeler MB","year":"1999","journal-title":"Int J Periodontics Restor Dent"},{"key":"e_1_2_7_33_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcpe.13031"},{"key":"e_1_2_7_34_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.1997.68.9.890"},{"key":"e_1_2_7_35_1","doi-asserted-by":"publisher","DOI":"10.1111\/jerd.12337"},{"issue":"9","key":"e_1_2_7_36_1","first-page":"739","article-title":"Clinical evaluation of a porcine acellular dermal matrix for the treatment of multiple adjacent class I, II, and III gingival recessions using the modified coronally advanced tunnel technique","volume":"47","author":"Cosgarea R","year":"2016","journal-title":"Quintessence Int"},{"key":"e_1_2_7_37_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2003.74.5.741"},{"key":"e_1_2_7_38_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2001.72.8.998"},{"key":"e_1_2_7_39_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2001.72.11.1477"},{"key":"e_1_2_7_40_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2002.73.12.1405"},{"key":"e_1_2_7_41_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.1992.tb01148.x"},{"key":"e_1_2_7_42_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2005.76.12.2286"},{"key":"e_1_2_7_43_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00784-015-1614-1"},{"key":"e_1_2_7_44_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.proghi.2016.04.001"},{"key":"e_1_2_7_45_1","doi-asserted-by":"publisher","DOI":"10.1111\/prd.12214"},{"key":"e_1_2_7_46_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.2011.01767.x"},{"key":"e_1_2_7_47_1","doi-asserted-by":"publisher","DOI":"10.14219\/jada.archive.2009.0158"},{"key":"e_1_2_7_48_1","doi-asserted-by":"publisher","DOI":"10.4103\/0972-124X.184033"},{"key":"e_1_2_7_49_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.2010.01559.x"}],"container-title":["Journal of Esthetic and Restorative Dentistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fjerd.12624","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jerd.12624","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/jerd.12624","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jerd.12624","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,5]],"date-time":"2023-09-05T01:30:54Z","timestamp":1693877454000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/jerd.12624"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,7,24]]},"references-count":48,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2020,10]]}},"alternative-id":["10.1111\/jerd.12624"],"URL":"https:\/\/doi.org\/10.1111\/jerd.12624","archive":["Portico"],"relation":{},"ISSN":["1496-4155","1708-8240"],"issn-type":[{"value":"1496-4155","type":"print"},{"value":"1708-8240","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,7,24]]},"assertion":[{"value":"2020-01-07","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-06-19","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-07-24","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}