{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T01:28:20Z","timestamp":1747186100338,"version":"3.40.5"},"reference-count":31,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2024,4,2]],"date-time":"2024-04-02T00:00:00Z","timestamp":1712016000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Esthet Restor Dent"],"published-print":{"date-parts":[[2024,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>While connective tissue graft shrinkage is a well\u2010documented post\u2010transplantation reaction, there is a literature gap concerning hyperplastic tissue response. Despite its infrequent occurrence, investigation is warranted due to its capacity to compromise esthetics, disrupt lip dynamics, and promote food retention. Moreover, efforts to mitigate hyperplastic tissue response often prove challenging, and there is a potential risk of exacerbating gingival tissue rebound.<\/jats:p><\/jats:sec><jats:sec><jats:title>Clinical Considerations<\/jats:title><jats:p>This report presents a potential solution to managing tissue overgrowth after connective tissue grafting in five clinical cases. The patients underwent corrective surgery involving internal excision of excessive tissue while preserving the overlying mucosa. The surgical approach was tailored to excise hyperplastic tissue with minimal trauma, aiming to optimize esthetic outcomes. Subsequent follow\u2010up assessments spanning 1\u20135\u2009years demonstrated stable results, with no indications of relapse or recurrence of tissue overgrowth.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Within the limitations of this case series, surgical internal excision holds promise as a viable treatment modality for addressing post\u2010transplantation hyperplastic tissue response.<\/jats:p><\/jats:sec><jats:sec><jats:title>Clinical Significance<\/jats:title><jats:p>This case series addresses the challenge of uncontrolled tissue overgrowth following connective tissue grafting, a concern for which previous attempts have proven unsuccessful. Internal in\u2010toto excision emerges as a promising approach for effectively eliminating overgrown tissue, offering potential advancements in the clinical management of this complication.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jerd.13232","type":"journal-article","created":{"date-parts":[[2024,4,2]],"date-time":"2024-04-02T09:00:21Z","timestamp":1712048421000},"page":"1228-1235","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Management of hyperplastic tissue response following connective tissue grafting"],"prefix":"10.1111","volume":"36","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0707-4478","authenticated-orcid":false,"given":"Snjezana","family":"Pohl","sequence":"first","affiliation":[{"name":"Department of Oral Medicine and Periodontology University of Rijeka, Private Clinic Rident  Rijeka Croatia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Howard","family":"Gluckman","sequence":"additional","affiliation":[{"name":"Department of Periodontics University of Pennsylvania School of Dental Medicine  Philadelphia Pennsylvania USA"},{"name":"Department of Oral Medicine and Periodontics, School of Dentistry University of Western Cape  Cape Town South Africa"},{"name":"Dental School University of Sarajevo  Sarajevo Bosnia and 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