{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,8]],"date-time":"2025-11-08T08:13:18Z","timestamp":1762589598216,"version":"build-2065373602"},"reference-count":29,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2025,2,27]],"date-time":"2025-02-27T00:00:00Z","timestamp":1740614400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100001807","name":"Funda\u00e7\u00e3o de Amparo \u00e0 Pesquisa do Estado de S\u00e3o Paulo","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001807","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001807","name":"Funda\u00e7\u00e3o de Amparo \u00e0 Pesquisa do Estado de S\u00e3o Paulo","doi-asserted-by":"publisher","award":["2022\/16029\u20107"],"award-info":[{"award-number":["2022\/16029\u20107"]}],"id":[{"id":"10.13039\/501100001807","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Esthet Restor Dent"],"published-print":{"date-parts":[[2025,6]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>This study aimed to evaluate the effect of limonene (LIM) on the bond strength of a universal adhesive system in self\u2010etch mode to caries\u2010affected dentin (CAD).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods<\/jats:title>\n                    <jats:p>\n                      Class I cavities were prepared in eighty sound human molars and divided into four groups (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u200920): Sound dentin (SD), SD\u2009+\u2009LIM (SD treated with LIM), CAD, and CAD\u2009+\u2009LIM (CAD treated with LIM). Following pH cycling, two layers of a universal adhesive system (Single Bond Universal, 3MESPE) were applied. After restoration (Filtek Z350, 3MESPE), samples were sectioned into 0.9\u2009mm\n                      <jats:sup>2<\/jats:sup>\n                      sticks and stored in distilled water at 37\u00b0C for 24\u2009h and 6\u2009months. Subsequently, sticks were subjected to microtensile bond strength testing. Data were analyzed using 2\u2010way ANOVA and Bonferroni's test (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.05). Fracture patterns were examined under optical and scanning electron microscopes.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>After 24\u2009h, SD\u2009+\u2009LIM showed lower bond strength than CAD but remained higher than CAD\u2009+\u2009LIM. CAD\u2009+\u2009LIM exhibited the lowest bond strength, regardless of aging. In SD\u2009+\u2009LIM, widened dentinal tubules were observed, accompanied by resin tags. In CAD\u2009+\u2009LIM, disorganized and unprotected collagen fibrils were identified, with fewer resin tags.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Limonene decreased the bond strength of the universal adhesive system in self\u2010etch mode to caries\u2010affected dentin.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Clinical Significance<\/jats:title>\n                    <jats:p>Limonene as a pretreatment in self\u2010etch adhesive protocols shows potential for enhancing the durability of adhesive restorations on sound dentin. However, its use on caries\u2010affected dentin could compromise adhesion, highlighting the need for careful consideration when applying it to compromised substrates.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jerd.13452","type":"journal-article","created":{"date-parts":[[2025,3,12]],"date-time":"2025-03-12T01:54:43Z","timestamp":1741744483000},"page":"1601-1608","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Effect of Limonene on the Bond Strength of a Universal Adhesive System to Caries\u2010Affected Dentin"],"prefix":"10.1111","volume":"37","author":[{"given":"Giulia Franc","family":"Liberatori","sequence":"first","affiliation":[{"name":"Department of Dental Materials and Prosthodontics Ribeir\u00e3o Preto School of Dentistry, University of S\u00e3o Paulo  Ribeir\u00e3o Preto S\u00e3o Paulo Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eduardo Jos\u00e9","family":"Soares","sequence":"additional","affiliation":[{"name":"Department of Pediatric Dentistry Ribeir\u00e3o Preto School of Dentistry, University of S\u00e3o Paulo  Ribeir\u00e3o Preto S\u00e3o Paulo Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0584-9401","authenticated-orcid":false,"given":"Rocio","family":"Geng Vivanco","sequence":"additional","affiliation":[{"name":"Department of Dental Materials and Prosthodontics Ribeir\u00e3o Preto School of Dentistry, University of S\u00e3o Paulo  Ribeir\u00e3o Preto S\u00e3o Paulo Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fernanda","family":"de Carvalho Panzeri Pires\u2010de\u2010Souza","sequence":"additional","affiliation":[{"name":"Department of Dental Materials and Prosthodontics Ribeir\u00e3o Preto School of Dentistry, University of S\u00e3o Paulo  Ribeir\u00e3o Preto S\u00e3o Paulo Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,2,27]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1177\/0022034514562833"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.dental.2017.11.005"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.2341\/14\u2010095\u2010BL"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1159\/000363582"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.dental.2012.11.002"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jdent.2014.03.013"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1155\/2019\/5268342"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1177\/0022034511435329"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.2341\/11\u2010501\u2010L"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmbbm.2022.105551"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.archoralbio.2017.12.028"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.dental.2013.10.012"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.3109\/13880209.2012.677847"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00784\u2010020\u201003545\u20105"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.3389\/fpls.2019.00012"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.archoralbio.2019.104638"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.1080\/10937404.2013.769418"},{"key":"e_1_2_10_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejps.2018.11.036"},{"key":"e_1_2_10_20_1","doi-asserted-by":"publisher","DOI":"10.1099\/jmm.0.000105"},{"key":"e_1_2_10_21_1","doi-asserted-by":"publisher","DOI":"10.1111\/eos.12947"},{"key":"e_1_2_10_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jdsr.2021.12.001"},{"key":"e_1_2_10_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jdsr.2011.03.002"},{"key":"e_1_2_10_24_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0027197"},{"key":"e_1_2_10_25_1","doi-asserted-by":"publisher","DOI":"10.3390\/bioengineering9010034"},{"key":"e_1_2_10_26_1","doi-asserted-by":"publisher","DOI":"10.4012\/dmj.2014\u2010083"},{"key":"e_1_2_10_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jdent.2021.103585"},{"key":"e_1_2_10_28_1","doi-asserted-by":"publisher","DOI":"10.4012\/dmj.2012\u2010243"},{"key":"e_1_2_10_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.archoralbio.2009.09.007"},{"key":"e_1_2_10_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jdent.2011.03.002"}],"container-title":["Journal 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