{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,5]],"date-time":"2026-06-05T21:08:38Z","timestamp":1780693718072,"version":"3.54.1"},"reference-count":55,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2025,6,21]],"date-time":"2025-06-21T00:00:00Z","timestamp":1750464000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2025,6,21]],"date-time":"2025-06-21T00:00:00Z","timestamp":1750464000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Esthet Restor Dent"],"published-print":{"date-parts":[[2025,11]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To compare clinical outcomes of cyanoacrylate adhesive (GLU) and sutures (SUT) for the fixation of free gingival grafts (FGG) around natural teeth.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods<\/jats:title>\n                    <jats:p>A systematic search of MEDLINE, Embase, Cochrane Library, Scopus, and Google Scholar was conducted up to March 2025. Randomized controlled trials (RCTs) comparing GLU and SUT as fixation methods for FGG were included in a meta\u2010analysis. Potential moderators, including publication year, follow\u2010up duration, sample size, baseline clinical parameters, and study\u2010level covariates, were investigated.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Ten RCTs were included. No significant differences were observed between GLU and SUT for recession reduction (mean difference [MD]\u2009=\u20090.49\u2009mm; 95% CI: \u22120.53 to 1.50;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.08), keratinized tissue (KT) height gain (MD\u2009=\u20090.01\u2009mm; 95% CI: \u22121.58 to 1.59;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.99), or graft shrinkage (MD\u2009=\u20090.26; 95% CI: \u22120.13 to 0.66;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.15). A statistically significant but clinically negligible difference favored GLU for probing depth reduction (MD\u2009=\u20090.063\u2009mm; 95% CI: 0.007 to 0.118;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.044). Meta\u2010regression identified smoking, tissue thickness, graft dimension, and follow\u2010up duration as moderators of treatment outcomes.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>No significant differences were observed between GLU and SUT in clinical outcomes following FGG procedures around natural teeth.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jerd.13504","type":"journal-article","created":{"date-parts":[[2025,6,21]],"date-time":"2025-06-21T06:26:04Z","timestamp":1750487164000},"page":"2368-2378","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Cyanoacrylate Adhesive Versus Sutures for Free Gingival Graft Fixation: A Systematic Review and Meta\u2010Analysis of Clinical Outcomes"],"prefix":"10.1111","volume":"37","author":[{"given":"Axelle","family":"Negre","sequence":"first","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery Univ. Lille, CHU Lille  Lille France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kadiatou","family":"Sy","sequence":"additional","affiliation":[{"name":"Universit\u00e9 de Lyon, Lyon, Universit\u00e9 Lyon 1, Laboratoire Des Multimat\u00e9riaux et Interfaces UMR CNRS 5615, Facult\u00e9 D'odontologie  Lyon France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6581-2104","authenticated-orcid":false,"given":"Hamoun","family":"Sabri","sequence":"additional","affiliation":[{"name":"Department of Periodontics and Oral Medicine University of Michigan School of Dentistry  Ann Arbor Michigan USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-3842-6150","authenticated-orcid":false,"given":"Khushboo","family":"Kalani","sequence":"additional","affiliation":[{"name":"Department of Periodontics and Oral Medicine University of Michigan School of Dentistry  Ann Arbor Michigan USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4238-1799","authenticated-orcid":false,"given":"Hom\u2010Lay","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Periodontics and Oral Medicine University of Michigan School of Dentistry  Ann Arbor Michigan USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4305-1353","authenticated-orcid":false,"given":"Kevimy","family":"Agossa","sequence":"additional","affiliation":[{"name":"Department of Periodontics and Oral Medicine University of Michigan School of Dentistry  Ann Arbor Michigan USA"},{"name":"Department of Periodontology School of Dentistry, U1008 \u2010 Advanced Drug Delivery Systems Univ. Lille, CHU Lille, INSERM  Lille France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,6,21]]},"reference":[{"issue":"3","key":"e_1_2_11_2_1","first-page":"121","article-title":"Free Autogenous Gingival Grafts. I. Principles of Successful Grafting","volume":"6","author":"Sullivan H. C.","year":"1968","journal-title":"Periodontics"},{"issue":"4","key":"e_1_2_11_3_1","first-page":"327","article-title":"Gingival Grafting in Periodontal Practice: Results of 103 Consecutive Surgeries in 82 Patients","volume":"28","author":"Horning G. M.","year":"2008","journal-title":"International Journal of Periodontics and Restorative Dentistry"},{"issue":"2","key":"e_1_2_11_4_1","first-page":"73","article-title":"Periodontal Soft Tissue Non\u2010Root Coverage Procedures: A Consensus Report From the AAP Regeneration Workshop","volume":"86","author":"Scheyer E. 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