{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,15]],"date-time":"2025-11-15T06:58:34Z","timestamp":1763189914020,"version":"3.45.0"},"reference-count":32,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2025,8,18]],"date-time":"2025-08-18T00:00:00Z","timestamp":1755475200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100016209","name":"Bilimsel Ara\u015ft\u0131rma Projeleri, Erciyes \u00dcniversitesi","doi-asserted-by":"publisher","award":["TKB\u20102021\u201011317"],"award-info":[{"award-number":["TKB\u20102021\u201011317"]}],"id":[{"id":"10.13039\/501100016209","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Esthet Restor Dent"],"published-print":{"date-parts":[[2025,12]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>This study aimed to compare the effects of nano\u2010silver fluoride (SDF), casein phosphopeptide\u2010amorphous calcium phosphate fluoride (CPP\u2010ACPF), and boron nitride (BN) on the remineralization of artificial initial enamel lesions.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods<\/jats:title>\n                    <jats:p>\n                      A total of 32 sound permanent maxillary incisor teeth were used in this study. Three 2\u2009\u00d7\u20092\u2009mm sections were obtained from each tooth. One section from each tooth remained untreated and was used as a control; the second section was demineralized and served as a demineralization control, while the third section was subjected to remineralization treatment following demineralization. The samples were randomly assigned to four groups, each containing eight teeth (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u20098). The study groups were as follows: Group 1 (Control): Stored in artificial saliva for 2\u2009weeks; Group 2: SDF\u2010treated group; Group 3: CPP\u2010ACPF\u2010treated group; Group 4: BN\u2010treated group. Following demineralization and remineralization treatments, the samples were evaluated using surface microhardness, surface roughness, SEM, SEM\u2013EDX, and QLF tests. The obtained data were statistically analyzed.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      When the surface hardness of the samples was compared after demineralization and remineralization treatments, a statistically significant increase in surface hardness was observed in the SDF, CPP\u2010ACPF, and BN groups after remineralization applications (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.05). When the Ca and Ca\/P ratios before and after remineralization treatments were compared, a statistically significant increase was observed in the CPP\u2010ACPF and BN groups, while a statistically significant decrease was observed in the SDF group (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.05). When surface roughness values were compared before and after remineralization treatments, a statistically significant increase was observed after demineralization (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.05); however, a statistically significant decrease in surface roughness was observed after the application of SDF, CPP\u2010ACPF, and BN to the demineralized samples (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.05). When the \u0394F, \u0394Fmax, and \u0394Q values were compared before and after remineralization, a statistically significant decrease was observed in all three groups (SDF, CPP\u2010ACPF, and BN) after remineralization treatments (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.05).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>BN application appears to be promising in the remineralization of initial caries lesions.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Clinical Significance<\/jats:title>\n                    <jats:p>Given their bioactivity, chemical stability, and potential antimicrobial properties, BN nanoparticles may offer a novel approach for enhancing enamel repair in non\u2010invasive caries management strategies.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jerd.70022","type":"journal-article","created":{"date-parts":[[2025,8,18]],"date-time":"2025-08-18T07:07:02Z","timestamp":1755500822000},"page":"2546-2554","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Assessment of the Remineralization Potential of Boron Nitride Nanoparticles Versus Conventional Agents on Artificial Enamel Lesions"],"prefix":"10.1111","volume":"37","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9180-5610","authenticated-orcid":false,"given":"Hacer","family":"Balkaya","sequence":"first","affiliation":[{"name":"Department of Restorative Dentistry Erciyes University Faculty of Dentistry  Kayseri Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fehime Alkan","family":"Ayg\u00f6r","sequence":"additional","affiliation":[{"name":"Department of Restorative Dentistry Ankara Y\u0131ld\u0131r\u0131m Beyaz\u0131t University Faculty of Dentistry  Ankara Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sezer","family":"Demirbu\u011fa","sequence":"additional","affiliation":[{"name":"Department of Restorative Dentistry Erciyes University Faculty of Dentistry  Kayseri Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Seda","family":"Bakt\u0131r","sequence":"additional","affiliation":[{"name":"Department of Restorative Dentistry Erciyes University Faculty of Dentistry  Kayseri Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,8,18]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1834-7819.2008.00064.x"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1177\/154405910408301s08"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0003-9969(00)00017-0"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1177\/0895937409335621"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1177\/154405910708600507"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.5005\/jp-journals-10005-1715"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.4103\/1735-3327.174713"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M413504200"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.17796\/jcpd.39.2.yn2r54nw24l03741"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jdent.2012.03.009"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10856-014-5221-5"},{"issue":"1","key":"e_1_2_10_13_1","first-page":"129","article-title":"The Physiological Role of Boron in Mineral Metabolism","volume":"66","author":"Nielsen F. 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