{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T01:35:23Z","timestamp":1790645723906,"version":"4.1.0"},"reference-count":12,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2014,11,10]],"date-time":"2014-11-10T00:00:00Z","timestamp":1415577600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Eukaryotic Microbiology"],"published-print":{"date-parts":[[2015,5]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:p><jats:italic>Hammondia hammondi<\/jats:italic> and <jats:italic>Toxoplasma gondii<\/jats:italic> are feline coccidians that are morphologically, antigenically, and phylogenitically related. Both parasites multiply asexually and sexually in feline intestinal enterocytes, but <jats:italic>H. hammondi<\/jats:italic> remains confined to enterocytes whereas <jats:italic>T. gondii<\/jats:italic> also parasitizes extra\u2010intestinal tissues of the cat. Here, we studied multiplication of <jats:italic>H. hammondi<\/jats:italic> in feline intestine and compared with <jats:italic>T. gondii<\/jats:italic> cycle. Five parasite\u2013free cats were inoculated orally with tissue cysts and free bradyzoites from skeletal muscles of gamma interferon gene knockout mice and killed at 1, 3, 4, 6, and 7\u00a0d later. At 1 and 3\u00a0d post inoculation (<jats:styled-content style=\"fixed-case\">DPI<\/jats:styled-content>), numerous individual intracellular bradyzoites were detected in histological sections of small intestine. At 4 <jats:styled-content style=\"fixed-case\">DPI<\/jats:styled-content> only schizonts were found and they were located in enterocyte cytoplasm above the host cell nucleus. At 6 and 7 <jats:styled-content style=\"fixed-case\">DPI<\/jats:styled-content> both schizonts and gamonts were seen and they were located in enterocytes. Ultrastucturally, schizogonic and gametogonic development of <jats:italic>H. hammondi<\/jats:italic> was similar to <jats:italic>T. gondii<\/jats:italic>. However, in <jats:italic>H. hammondi<\/jats:italic> merozoites rhoptries were longer, and coiled and contained more micronemes than in <jats:italic>T. gondii<\/jats:italic>. Ultrastructural development is illustrated in detail.<\/jats:p>","DOI":"10.1111\/jeu.12188","type":"journal-article","created":{"date-parts":[[2014,10,14]],"date-time":"2014-10-14T04:21:00Z","timestamp":1413260460000},"page":"346-352","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Life Cycle of <i>Hammondia hammondi<\/i> (Apicomplexa: Sarcocystidae) in Cats"],"prefix":"10.1111","volume":"62","author":[{"given":"Jitender P.","family":"Dubey","sequence":"first","affiliation":[{"name":"Animal Parasitic Diseases Laboratory Beltsville Agricultural Research Center Agricultural Research Service United States Department of Agriculture Beltsville Maryland 20705\u20102350 USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David J. P.","family":"Ferguson","sequence":"additional","affiliation":[{"name":"Nuffield Department of Clinical Laboratory Science University of Oxford John Radcliffe Hospital Oxford UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2014,11,10]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.2307\/3283823"},{"key":"e_1_2_7_3_1","volume-title":"Toxoplasmosis of Animals and Humans","author":"Dubey J. P.","year":"2010"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1550-7408.1972.tb03431.x"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0020-7519(03)00141-3"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1645\/12-51.1"},{"key":"e_1_2_7_7_1","first-page":"167","article-title":"Ultrastructural study of early stages of asexual multiplication and microgametogony of Toxoplasma gondii in the small intestine of the cat","volume":"82","author":"Ferguson D. J. P.","year":"1974","journal-title":"Acta Pathol. Microbiol. Scand. B."},{"key":"e_1_2_7_8_1","first-page":"491","article-title":"The ultrastructural development of the macrogamete and formation of the oocyst wall of Toxoplasma gondii","volume":"83","author":"Ferguson D. J. P.","year":"1975","journal-title":"Acta Pathol. Microbiol. Scand. 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