{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,23]],"date-time":"2026-01-23T12:38:29Z","timestamp":1769171909659,"version":"3.49.0"},"reference-count":27,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2022,12,17]],"date-time":"2022-12-17T00:00:00Z","timestamp":1671235200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Eukaryotic Microbiology"],"published-print":{"date-parts":[[2023,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:italic>Blastocystis<\/jats:italic> sp<jats:italic>.<\/jats:italic> is one of the most common intestinal parasites in humans and many animals. To further understand the infection of <jats:italic>Blastocystis hominis<\/jats:italic> (<jats:italic>B. hominis<\/jats:italic>) and the distribution of its genotype in some areas of Henan Province, China, 793 stool samples from outpatients and inpatients in Xinxiang City and Xinyang City, Henan Province were collected from April 2020 to July 2022. The samples were detected by polymerase chain reaction and analyzed by univariate analysis and logistic regression analysis. The results showed that the infection rates of <jats:italic>B. hominis<\/jats:italic> in Xinxiang and Xinyang were 10.97% (51\/465) and 10.98% (36\/328), respectively. Although there were no significant differences in <jats:italic>B. hominis<\/jats:italic> infection between gender, age, residence, and disease background, the incidence of hematochezia significantly differed from the incidence of abdominal pain, diarrhea, and constipation among participants (\u03c7<jats:sup>2<\/jats:sup>\u00a0=\u00a015.795, <jats:italic>p<\/jats:italic>\u00a0=\u00a00.002). A total of 87 positive samples were sequenced and compared with Basic Local Alignment Search Tool, and five subtypes (ST1, ST3, ST4, ST6, and ST7) were identified, of which ST3 was the dominant subtype (63.22%, 55\/87), followed by ST7 (17.24%, 15\/87) and ST1 (16.09%, 14\/87). This is the first study that analyzed the prevalence and subtype distribution of <jats:italic>B. hominis<\/jats:italic> in southern and northern Henan Province, thus providing new insights into the epidemiology of <jats:italic>B. hominis<\/jats:italic>.<\/jats:p>","DOI":"10.1111\/jeu.12960","type":"journal-article","created":{"date-parts":[[2022,12,7]],"date-time":"2022-12-07T18:33:28Z","timestamp":1670438008000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Molecular prevalence and subtypes distribution of <i>Blastocystis<\/i> sp. among outpatients and inpatients in north and south areas of Henan Province, China"],"prefix":"10.1111","volume":"70","author":[{"given":"Xuefang","family":"Mei","sequence":"first","affiliation":[{"name":"Xinxiang Key Laboratory of Pathogenic Biology Department of Pathogenic Biology School of Basic Medical Sciences Xinxiang Medical University  Xinxiang 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