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The open reading frames (ORF) of <jats:italic>tyr<\/jats:italic> and <jats:italic>tyrp1<\/jats:italic> encode putative peptides of 533 and 526 amino acids (amino\u2010acid), both of which possess two conserved copper binding sites. The homologous identities of deduced amino\u2010acid sequences showed that both Tyr and Tyrp1 of <jats:italic>T. fulvidraco<\/jats:italic> share considerable similarity with that of channel catfish <jats:styled-content style=\"fixed-case\"><jats:italic>Ictalurus punctatus<\/jats:italic><\/jats:styled-content>. Both <jats:italic>tyr<\/jats:italic> and <jats:italic>tyrp1<\/jats:italic> were expressed in a wide range of adult tissues. <jats:italic>Tyr<\/jats:italic> gene had the highest expression level in the brain of both normal and albino <jats:italic>T. fulvidraco<\/jats:italic>. <jats:italic>Tyrp1<\/jats:italic> had the highest expression level in the skin of normal groups, and the fin of albino groups. The messenger (m)RNA expressions of <jats:italic>tyr<\/jats:italic> and <jats:italic>tyrp1<\/jats:italic> were detectable at different early developmental stages and varied with embryonic and larval growth. <jats:italic>Tyr<\/jats:italic> and <jats:italic>tyrp1<\/jats:italic> mRNA have obvious tissue specificity both in normal and albino <jats:italic>T. fulvidraco<\/jats:italic> and higher expression levels were detected in the normal group revealing that <jats:italic>tyr<\/jats:italic> and <jats:italic>tyrp1<\/jats:italic> may have an important role in pigmentation. These results will provide useful data for understanding the molecular mechanism of melanin formation and the occurrence of albinism in <jats:italic>T. fulvidraco<\/jats:italic>.<\/jats:p>","DOI":"10.1111\/jfb.13556","type":"journal-article","created":{"date-parts":[[2018,2,21]],"date-time":"2018-02-21T18:51:43Z","timestamp":1519239103000},"page":"979-998","source":"Crossref","is-referenced-by-count":28,"title":["Molecular cloning and expression analysis of <i>tyr<\/i> and <i>tyrp1<\/i> genes in normal and albino yellow catfish <i>Tachysurus fulvidraco<\/i>"],"prefix":"10.1111","volume":"92","author":[{"given":"X. T.","family":"Zhang","sequence":"first","affiliation":[{"name":"Department of Aquatic Animal Medicines, College of Fisheries Huazhong Agricultural University  Wuhan Hubei 430070 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K. 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