{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,26]],"date-time":"2026-06-26T08:52:00Z","timestamp":1782463920179,"version":"3.54.5"},"reference-count":33,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2019,4,15]],"date-time":"2019-04-15T00:00:00Z","timestamp":1555286400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Fish Biology"],"published-print":{"date-parts":[[2019,5]]},"abstract":"<jats:p>Through the analysis of behavioural changes, this study demonstrates that methadone has behavioural, but not analgesic, effects on <jats:styled-content style=\"fixed-case\"><jats:italic>Oreochromis niloticus<\/jats:italic><\/jats:styled-content>. It provides information that suggests the drug has sedative abilities, as the recovery time was shorter in the fish receiving methadone. Future research, with different doses and stimuli, is required to provide more information about analgesia.<\/jats:p>","DOI":"10.1111\/jfb.13959","type":"journal-article","created":{"date-parts":[[2019,3,14]],"date-time":"2019-03-14T08:40:11Z","timestamp":1552552811000},"page":"823-827","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Behavioural and physiological effects of methadone in the perioperative period on the Nile tilapia <scp><i>Oreochromis niloticus<\/i><\/scp>"],"prefix":"10.1111","volume":"94","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4521-8738","authenticated-orcid":false,"given":"Roberta M.","family":"Crivelaro","sequence":"first","affiliation":[{"name":"Department of Small Animal Medicine and Surgery, College of Agrarian and Veterinarian Sciences, Via de acesso, professor Paulo Donato Castellani S\u00e3o Paulo State University (Unesp)  Jaboticabal Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roberto","family":"Thiesen","sequence":"additional","affiliation":[{"name":"Pampa Federal University (Unipampa)  Uruguaiana Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcela","family":"Aldrovani","sequence":"additional","affiliation":[{"name":"Department of Small Animal Medicine and Surgery, College of Agrarian and Veterinarian Sciences, Via de acesso, professor Paulo Donato Castellani S\u00e3o Paulo State University (Unesp)  Jaboticabal Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paloma E.S.","family":"Silva","sequence":"additional","affiliation":[{"name":"Department of Small Animal Medicine and Surgery, College of Agrarian and Veterinarian Sciences, Via de acesso, professor Paulo Donato Castellani S\u00e3o Paulo State University (Unesp)  Jaboticabal Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexandre A.F.","family":"Barros Sobrinho","sequence":"additional","affiliation":[{"name":"Department of Small Animal Medicine and Surgery, College of Agrarian and Veterinarian Sciences, Via de acesso, professor Paulo Donato Castellani S\u00e3o Paulo State University (Unesp)  Jaboticabal Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paola C.","family":"Moraes","sequence":"additional","affiliation":[{"name":"Department of Small Animal Medicine and Surgery, College of Agrarian and Veterinarian Sciences, Via de acesso, professor Paulo Donato Castellani S\u00e3o Paulo State University (Unesp)  Jaboticabal Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2019,4,15]]},"reference":[{"key":"e_1_2_2_2_1","doi-asserted-by":"publisher","DOI":"10.2460\/javma.243.6.882"},{"key":"e_1_2_2_3_1","doi-asserted-by":"publisher","DOI":"10.1590\/S1519-69842010000200027"},{"key":"e_1_2_2_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/9781119421375.ch15"},{"key":"e_1_2_2_5_1","doi-asserted-by":"crossref","unstructured":"Broom D. M.(2016).Fish brains and behavior indicate capacity for feeling pain.Animal Sentience. Available athttp:\/\/animalstudiesrepository.org\/cgi\/viewcontent.cgi?article=1031&context=animsent.","DOI":"10.51291\/2377-7478.1031"},{"key":"e_1_2_2_6_1","doi-asserted-by":"publisher","DOI":"10.1213\/01.ANE.0000099723.75548.DF"},{"issue":"3666","key":"e_1_2_2_7_1","first-page":"1","article-title":"Induction of myocardial infarction in adult zebrafish using cryoinjury","volume":"18","author":"Chablais F.","year":"2012","journal-title":"Journal of Visualized Experiments"},{"key":"e_1_2_2_8_1","volume-title":"Veterinary Anaesthesia","author":"Clarke K. W","year":"2014"},{"key":"e_1_2_2_9_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-62703-505-7_27"},{"key":"e_1_2_2_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1096-9861(19960311)366:3<448::AID-CNE6>3.0.CO;2-4"},{"key":"e_1_2_2_11_1","doi-asserted-by":"publisher","DOI":"10.1638\/1042-7260(2003)034[0153:EOPAMF]2.0.CO;2"},{"key":"e_1_2_2_12_1","doi-asserted-by":"publisher","DOI":"10.1186\/2193-1801-2-76"},{"key":"e_1_2_2_13_1","doi-asserted-by":"publisher","DOI":"10.1515\/pjvs-2015-0019"},{"key":"e_1_2_2_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1095-8649.2012.03409.x"},{"key":"e_1_2_2_15_1","first-page":"221","article-title":"Behavioral and clinical pathology changes in koi carp (Cyprinus carpio) subjected to anesthesia and surgery with and without intra\u2010operative analgesics","volume":"55","author":"Harms C. A.","year":"2005","journal-title":"Comparative Medicine"},{"key":"e_1_2_2_16_1","doi-asserted-by":"publisher","DOI":"10.1071\/MF9940917"},{"key":"e_1_2_2_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/0024-3205(94)00937-6"},{"key":"e_1_2_2_18_1","doi-asserted-by":"publisher","DOI":"10.1002\/9781119421375.ch11"},{"key":"e_1_2_2_19_1","volume-title":"Tilapia: Biology, Culture and Nutrition","author":"Lim C. E.","year":"2006"},{"key":"e_1_2_2_20_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0173418"},{"key":"e_1_2_2_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.applanim.2011.06.009"},{"key":"e_1_2_2_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.applanim.2009.03.015"},{"key":"e_1_2_2_23_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.1077857"},{"key":"e_1_2_2_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.applanim.2008.01.016"},{"key":"e_1_2_2_25_1","doi-asserted-by":"publisher","DOI":"10.1080\/20026491051668"},{"key":"e_1_2_2_26_1","doi-asserted-by":"publisher","DOI":"10.1111\/faf.12010"},{"key":"e_1_2_2_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.applanim.2016.12.003"},{"key":"e_1_2_2_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0168-1591(03)00113-8"},{"key":"e_1_2_2_29_1","doi-asserted-by":"publisher","DOI":"10.1242\/jeb.088823"},{"key":"e_1_2_2_30_1","doi-asserted-by":"publisher","DOI":"10.1067\/S1526-5900(03)00717-X"},{"key":"e_1_2_2_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.anbehav.2014.09.007"},{"key":"e_1_2_2_32_1","doi-asserted-by":"publisher","DOI":"10.1080\/00028487.2013.856814"},{"key":"e_1_2_2_33_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0147747"},{"key":"e_1_2_2_34_1","doi-asserted-by":"publisher","DOI":"10.1089\/zeb.2009.0594"}],"container-title":["Journal of Fish Biology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fjfb.13959","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jfb.13959","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/jfb.13959","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jfb.13959","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,10]],"date-time":"2023-09-10T11:41:44Z","timestamp":1694346104000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/jfb.13959"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,4,15]]},"references-count":33,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2019,5]]}},"alternative-id":["10.1111\/jfb.13959"],"URL":"https:\/\/doi.org\/10.1111\/jfb.13959","archive":["Portico"],"relation":{},"ISSN":["0022-1112","1095-8649"],"issn-type":[{"value":"0022-1112","type":"print"},{"value":"1095-8649","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,4,15]]},"assertion":[{"value":"2019-02-05","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-03-13","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-04-15","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}