{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,25]],"date-time":"2026-03-25T19:42:30Z","timestamp":1774467750245,"version":"3.50.1"},"reference-count":35,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2020,2,13]],"date-time":"2020-02-13T00:00:00Z","timestamp":1581552000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Fish Biology"],"published-print":{"date-parts":[[2020,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The opioid peptides are involved in the regulation of neuroendocrine functions in vertebrates. Nonetheless, the influence of an opioid peptide, dynorphin A (DYN), on reproduction in fish is understudied. The aim of this work was to study the influence of DYN on the pituitary\u2010ovary axis in <jats:styled-content style=\"fixed-case\"><jats:italic>Oreochromis mossambicus<\/jats:italic><\/jats:styled-content>. Daily injections (ip) of 250\u2009\u03bcg DYN kg<jats:sup>\u22121<\/jats:sup> body weight for 22\u2009days during the ovarian cycle caused a reduction in the intensity and the per cent area of luteinizing hormone (LH) immunoreactive content in the proximal pars distalis region of the pituitary gland compared with an intense immunostaining in time\u2010matched controls. In the ovary, DYN treatment caused a decrease in the number of stage I (previtellogenic) follicles compared with time\u2010matched controls. No difference was observed in the number of stage IV (vitellogenic) follicles among different experimental groups, whereas the numbers of stage II and stage III follicles (previtellogenic) were higher in DYN\u2010treated fish than in time\u2010matched controls. Nonetheless, there was a reduction in the number of stage V (preovulatory) follicles in DYN\u2010treated fish compared with time\u2010matched controls. Taken together, these results indicate that DYN exerts an inhibitory effect on follicular recruitment at the late vitellogenic stage, through the suppression of LH secretion in fish.<\/jats:p>","DOI":"10.1111\/jfb.14269","type":"journal-article","created":{"date-parts":[[2020,1,31]],"date-time":"2020-01-31T11:38:11Z","timestamp":1580470691000},"page":"747-754","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["The opioid peptide dynorphin suppresses pituitary\u2010ovary axis in the tilapia <scp><i>Oreochromis mossambicus<\/i><\/scp>"],"prefix":"10.1111","volume":"96","author":[{"family":"Vijayalaxmi","sequence":"first","affiliation":[{"name":"Neuroendocrinology Research Laboratory, Department of Studies in Zoology Karnatak University  Dharwad India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5662-534X","authenticated-orcid":false,"given":"C.B.","family":"Ganesh","sequence":"additional","affiliation":[{"name":"Neuroendocrinology Research Laboratory, Department of Studies in Zoology Karnatak University  Dharwad India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2020,2,13]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.rbmo.2012.02.007"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/jfb.14183"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/0016-6480(88)90093-7"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00297545"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.82.12.4291"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10695-012-9643-z"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/jez.1781"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.6120570"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbi.2008.10.003"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1677\/joe.0.1430565"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1177\/1933719109336619"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1677\/joe.0.1370049"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.96.4.1722"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0016-6480(03)00186-2"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10695-012-9725-y"},{"key":"e_1_2_8_17_1","first-page":"45","article-title":"Follicular development status and profile of 17\u03b2 estradiol and cortisol levels during the spawning cycle in Oreochromis mossambicus (Peters)","volume":"61","author":"Ganesh C. 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