{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,24]],"date-time":"2026-07-24T10:04:30Z","timestamp":1784887470211,"version":"3.55.0"},"reference-count":89,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2026,3,12]],"date-time":"2026-03-12T00:00:00Z","timestamp":1773273600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,3,12]],"date-time":"2026-03-12T00:00:00Z","timestamp":1773273600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Fish Biology"],"published-print":{"date-parts":[[2026,7]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    This study examined the adverse effects of sublethal concentrations of cadmium (Cd) and the potential of curcumin (CUR) to mitigate Cd\u2010induced toxicity. We administered 1.5 and 3\u2009mg\/L of Cd and 100\u2009mg\/kg of CUR to fish (\n                    <jats:italic>Cyprinus carpio<\/jats:italic>\n                    ) separately and in combination over 14\u2009days. At the end of the experiments, various haematological and immunological parameters, oxidative stress levels and antioxidant parameters of fish were measured, and the differences between the groups were evaluated. Simultaneous CUR treatment with Cd reversed the changes in haematological parameters in fish, increased immune responses, reduced oxidative stress and normalized the impaired antioxidant enzyme activities. In summary, our study showed that dietary supplementation with CUR may be an effective strategy to reduce the toxic effects of Cd in carp.\n                  <\/jats:p>","DOI":"10.1111\/jfb.70384","type":"journal-article","created":{"date-parts":[[2026,3,12]],"date-time":"2026-03-12T14:35:07Z","timestamp":1773326107000},"page":"175-188","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Cadmium\u2010induced changes in haemato\u2010immunological, oxidative stress and antioxidant parameters of\n                    <i>Cyprinus carpio<\/i>\n                    : Protective role of curcumin"],"prefix":"10.1111","volume":"109","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5269-023X","authenticated-orcid":false,"given":"Ay\u015feg\u00fcl","family":"Pala","sequence":"first","affiliation":[{"name":"Department of Aquaculture and Diseases, Faculty of Fisheries Munzur University  Tunceli Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M\u00fccahit","family":"Ero\u011flu","sequence":"additional","affiliation":[{"name":"Department of Aquaculture Basic Sciences, Division of Basic Fisheries Sciences Faculty of Fisheries, Firat University  Elazig Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Serpil","family":"Mi\u015fe Yonar","sequence":"additional","affiliation":[{"name":"Department of Aquaculture, Faculty of Fisheries Firat University  Elazig Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"\u00dcnal","family":"\u0130spir","sequence":"additional","affiliation":[{"name":"Faculty of Agriculture Malatya Turgut \u00d6zal University, Su \u00fcr\u00fcnleri M\u00fchendisli\u011fi b\u00f6l\u00fcm\u00fc  Malatya Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9519-4247","authenticated-orcid":false,"given":"Muhammet Enis","family":"Yonar","sequence":"additional","affiliation":[{"name":"Department of Aquaculture Basic Sciences, Division of Basic Fisheries Sciences Faculty of Fisheries, Firat University  Elazig Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,3,12]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/jsfa.11372"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.aquatox.2020.105406"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/jwas.12349"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0076-6879(84)05016-3"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.aquaculture.2020.736030"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1080\/10807039.2018.1469398"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.3390\/ani11061779"},{"key":"e_1_2_9_9_1","volume-title":"Red cell metabolism, a manual of biochemical methods","author":"Beutler E.","year":"1975"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10695-019-00709-3"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.aqrep.2021.100678"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.aquatox.2021.105775"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhazmat.2018.12.014"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fsi.2021.12.004"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fsi.2021.01.002"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.aquatox.2018.01.012"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10534-010-9329-x"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11356-018-04113-x"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10695-022-01052-w"},{"issue":"4","key":"e_1_2_9_20_1","first-page":"725","article-title":"Effect of cadmium on hematological indices of common carp (Cyprinus carpio L.)","volume":"72","author":"Drastichova J.","year":"2004","journal-title":"Bulletin of Environmental Contamination and Toxicology"},{"key":"e_1_2_9_21_1","first-page":"83","article-title":"Cambios en la velocidad de nado como indicador del efecto t\u00f3xico del Cadmio en Astyanax fasciatus y Australoheros facetum","volume":"26","author":"Eissa B. L.","year":"2009","journal-title":"Biolog\u00eda Acu\u00e1tica"},{"key":"e_1_2_9_22_1","doi-asserted-by":"publisher","DOI":"10.3390\/fishes8040208"},{"key":"e_1_2_9_23_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10499-024-01500-9"},{"key":"e_1_2_9_24_1","doi-asserted-by":"publisher","DOI":"10.12980\/JCLM.2.2014J57"},{"key":"e_1_2_9_25_1","first-page":"101","volume-title":"Techniques in fish immunology","author":"Ellis A. E.","year":"1990"},{"key":"e_1_2_9_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/0003-9861(59)90090-6"},{"key":"e_1_2_9_27_1","doi-asserted-by":"publisher","DOI":"10.1111\/raq.12433"},{"key":"e_1_2_9_28_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10499-024-01622-0"},{"key":"e_1_2_9_29_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12011-021-02852-6"},{"key":"e_1_2_9_30_1","doi-asserted-by":"publisher","DOI":"10.1504\/IJENVH.2019.108681"},{"issue":"001","key":"e_1_2_9_31_1","first-page":"1","article-title":"Effect of heavy metals on fishes: Toxicity and bioaccumulation","volume":"18","author":"Garai P.","year":"2021","journal-title":"Journal of Clinical Toxicology"},{"key":"e_1_2_9_32_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ecoenv.2021.112318"},{"key":"e_1_2_9_33_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fsi.2016.03.024"},{"key":"e_1_2_9_34_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fsi.2019.06.053"},{"key":"e_1_2_9_35_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9258(19)42083-8"},{"key":"e_1_2_9_36_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.aquatox.2021.106014"},{"key":"e_1_2_9_37_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.aquatox.2021.106023"},{"key":"e_1_2_9_38_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cbpc.2020.108942"},{"key":"e_1_2_9_39_1","doi-asserted-by":"publisher","DOI":"10.14715\/cmb\/2017.63.1.3"},{"key":"e_1_2_9_40_1","doi-asserted-by":"publisher","DOI":"10.2754\/avb200776030493"},{"issue":"3","key":"e_1_2_9_41_1","first-page":"566","article-title":"Effect of dietary vitamin E supplementation on the blood parameters of Nile tilapia (Oreochromis niloticus)","volume":"21","author":"Ispir U.","year":"2011","journal-title":"Journal of Animal and Plant Sciences"},{"key":"e_1_2_9_42_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.aquaculture.2016.05.040"},{"key":"e_1_2_9_43_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fct.2010.07.017"},{"key":"e_1_2_9_44_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.envres.2023.116600"},{"key":"e_1_2_9_45_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.aqrep.2021"},{"key":"e_1_2_9_46_1","doi-asserted-by":"publisher","DOI":"10.3390\/toxics10100622"},{"key":"e_1_2_9_47_1","first-page":"265","article-title":"Protein measurement with the Folin\u2010phenol reagent","volume":"193","author":"Lowry O. H.","year":"1951","journal-title":"Journal of Biochemistry"},{"key":"e_1_2_9_48_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.aquaculture.2017.03.043"},{"key":"e_1_2_9_49_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10695-010-9418-3"},{"key":"e_1_2_9_50_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fsi.2019.12.074"},{"key":"e_1_2_9_51_1","doi-asserted-by":"publisher","DOI":"10.14715\/cmb\/2017.63.3.13"},{"issue":"1","key":"e_1_2_9_52_1","first-page":"59","article-title":"The effect of curcimin on some haematological parameters in rainbow trout (Oncorhynchus mykiss, Walbaum, 1792)","volume":"6","author":"Mi\u015fe Yonar S.","year":"2013","journal-title":"B\u0130BAD"},{"key":"e_1_2_9_53_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.chemosphere.2024.142097"},{"key":"e_1_2_9_54_1","doi-asserted-by":"publisher","DOI":"10.3382\/ps.0310735"},{"key":"e_1_2_9_55_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11356-020-10980-0"},{"key":"e_1_2_9_56_1","doi-asserted-by":"publisher","DOI":"10.1002\/jemt.23536"},{"key":"e_1_2_9_57_1","doi-asserted-by":"publisher","DOI":"10.15835\/nsb346299"},{"key":"e_1_2_9_58_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ecoenv.2016.03.046"},{"key":"e_1_2_9_59_1","doi-asserted-by":"publisher","DOI":"10.1016\/0003-2697(66)90167-9"},{"key":"e_1_2_9_60_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhazmat.2014.04.051"},{"key":"e_1_2_9_61_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0165-2427(97)00048-2"},{"key":"e_1_2_9_62_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2109.2008.02105.x"},{"key":"e_1_2_9_63_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1439-0426.2004.00606.x"},{"issue":"10","key":"e_1_2_9_64_1","first-page":"2806","article-title":"Effect of short\u2010term cypermethrin exposure on oxidant\u2013antioxidant balance in the whole body of rainbow trout fry (Oncorhynchus mykiss)","volume":"20","author":"Sakin F.","year":"2011","journal-title":"Fresenius Environmental Bulletin"},{"issue":"10","key":"e_1_2_9_65_1","first-page":"989","article-title":"Changes in selected immunological parameters and oxidative stress responses in different organs of Oncorhynchus mykiss exposed to ivermectin","volume":"63","author":"Sakin F.","year":"2012","journal-title":"Revista de Chimie"},{"key":"e_1_2_9_66_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pestbp.2011.04.002"},{"key":"e_1_2_9_67_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2109.2007.01883.x"},{"issue":"5","key":"e_1_2_9_68_1","first-page":"1837","article-title":"Antioxidant responses of rainbow trout (Oncorhynchus mykiss) gills after exposure to hydrogen peroxide","volume":"24","author":"Seker E.","year":"2015","journal-title":"Fresenius Environmental Bulletin"},{"key":"e_1_2_9_69_1","doi-asserted-by":"publisher","DOI":"10.21608\/ejap.2012.94324"},{"key":"e_1_2_9_70_1","doi-asserted-by":"publisher","DOI":"10.1016\/0165-2427(94)90062-0"},{"key":"e_1_2_9_71_1","unstructured":"Siwicki A. K. Anderson D. P. &Waluga J.(1993).Fish diseases diagnosis and prevention methods. Fish diseases diagnosis and prevention methods."},{"key":"e_1_2_9_72_1","doi-asserted-by":"publisher","DOI":"10.2754\/avb199867040295"},{"key":"e_1_2_9_73_1","doi-asserted-by":"publisher","DOI":"10.3390\/antiox12020243"},{"key":"e_1_2_9_74_1","doi-asserted-by":"publisher","DOI":"10.1093\/clinchem\/34.3.497"},{"key":"e_1_2_9_75_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fsi.2012.11.003"},{"key":"e_1_2_9_76_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10695-025-01506-x"},{"key":"e_1_2_9_77_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.anireprosci.2016.06.008"},{"key":"e_1_2_9_78_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fsi.2019.03.047"},{"key":"e_1_2_9_79_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.aaf.2023.06.001"},{"key":"e_1_2_9_80_1","doi-asserted-by":"publisher","DOI":"10.3390\/ani13162625"},{"key":"e_1_2_9_81_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.aqrep.2022.101128"},{"key":"e_1_2_9_82_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.aqrep.2024.102516"},{"key":"e_1_2_9_83_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cbpc.2019.04.012"},{"key":"e_1_2_9_84_1","doi-asserted-by":"publisher","DOI":"10.3390\/nu10101553"},{"key":"e_1_2_9_85_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ecoenv.2017.12.065"},{"issue":"2","key":"e_1_2_9_86_1","first-page":"111","article-title":"Investigation of some immunological parameters in pollen\u2010injected Cyprinus carpio","volume":"38","author":"Yonar M. E.","year":"2024","journal-title":"F\u0131rat University Journal of Health Sciences (Veterinary)"},{"key":"e_1_2_9_87_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fsi.2019.03.038"},{"key":"e_1_2_9_88_1","doi-asserted-by":"publisher","DOI":"10.3390\/toxics12100699"},{"key":"e_1_2_9_89_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10482-016-0819-x"},{"key":"e_1_2_9_90_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.aquatox.2016.09.012"}],"container-title":["Journal of Fish Biology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jfb.70384","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/jfb.70384","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jfb.70384","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,24]],"date-time":"2026-07-24T09:27:07Z","timestamp":1784885227000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/jfb.70384"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,3,12]]},"references-count":89,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2026,7]]}},"alternative-id":["10.1111\/jfb.70384"],"URL":"https:\/\/doi.org\/10.1111\/jfb.70384","archive":["Portico"],"relation":{},"ISSN":["0022-1112","1095-8649"],"issn-type":[{"value":"0022-1112","type":"print"},{"value":"1095-8649","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,3,12]]},"assertion":[{"value":"2025-09-29","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-02-15","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-03-12","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}