{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,17]],"date-time":"2026-10-17T04:41:23Z","timestamp":1792212083558,"version":"4.4.0"},"reference-count":44,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2026,8,31]],"date-time":"2026-08-31T00:00:00Z","timestamp":1788134400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,8,31]],"date-time":"2026-08-31T00:00:00Z","timestamp":1788134400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100012166","name":"National Key Research and Development Program of China","doi-asserted-by":"publisher","award":["2022YFC2601303"],"award-info":[{"award-number":["2022YFC2601303"]}],"id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Fish Biology"],"published-print":{"date-parts":[[2026,10]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    The introduction of aquaculture\u2010derived hybrid fishes into natural marine ecosystems raises critical questions regarding their physiological capacity to acclimate to novel environments. The hybrid grouper (\n                    <jats:italic>Epinephelus lanceolatus<\/jats:italic>\n                    \u2642\u2009\u00d7\u2009\n                    <jats:italic>E. fuscoguttatus<\/jats:italic>\n                    \u2640), a widely farmed teleost in southern China, has increasingly been reported in coastal habitats following escape events. However, the gut microbiome\u2010associated mechanisms underlying its acclimation to natural conditions remain poorly understood. Here, we compared the gut microbiomes of cultured and wild\u2010caught individuals collected from two coastal regions using 16S rRNA gene sequencing integrated with functional prediction and microbial co\u2010occurrence network analysis. Following their transition to natural habitats, escapees retained some dominant aquaculture\u2010associated genera (\n                    <jats:italic>Halomonas<\/jats:italic>\n                    ,\n                    <jats:italic>Cetobacterium, Photobacterium<\/jats:italic>\n                    and\n                    <jats:italic>Vibrio<\/jats:italic>\n                    ) and clustered closely with local cultured counterparts rather than rearing condition. Beneath this partial taxonomic stability, however, the significant difference in intestinal microbiome between wild\u2010caught and cultured individuals was manifested in predicted functional pathways and microbial interaction networks, characterized by shifts in immune\u2010related processes, energy metabolism and keystone taxa. These findings indicate that hybrid groupers respond to environmental transition through functional and association\u2010level plasticity rather than simple replacement of the gut microbial community. We propose that this dynamic microbiome rewiring may reflect microbiome\u2010level adjustments associated with environmental transition, offering a microbial perspective on the acclimation of aquaculture\u2010derived fishes to heterogeneous marine environments.\n                  <\/jats:p>","DOI":"10.1111\/jfb.70631","type":"journal-article","created":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T05:03:52Z","timestamp":1788239032000},"page":"2475-2487","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Gut microbiome reorganization as a signal of physiological acclimation in escaped hybrid grouper (\n                    <i>Epinephelus lanceolatus<\/i>\n                    \u2642\u2009\u00d7\u2009\n                    <i>E. fuscoguttatus<\/i>\n                    \u2640)"],"prefix":"10.1111","volume":"109","author":[{"given":"WangHui","family":"Song","sequence":"first","affiliation":[{"name":"State Key Laboratory of Mariculture Breeding, College of Ocean and Earth Sciences of Xiamen University  Xiamen China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"XueQing","family":"Du","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Mariculture Breeding, College of Ocean and Earth Sciences of Xiamen University  Xiamen China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiang","family":"Zhang","sequence":"additional","affiliation":[{"name":"School of Marine Biology and Fisheries, Hainan University  Haikou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1895-7620","authenticated-orcid":false,"given":"Jing","family":"Zhao","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Mariculture Breeding, College of Ocean and Earth Sciences of Xiamen University  Xiamen China"},{"name":"Fujian Ocean Innovation Center  Xiamen China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2734-4407","authenticated-orcid":false,"given":"ShaoXiong","family":"Ding","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Mariculture Breeding, College of Ocean and Earth Sciences of Xiamen University  Xiamen China"},{"name":"Fujian Ocean Innovation Center  Xiamen China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,8,31]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.aninu.2023.05.005"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-ecolsys-032522-015551"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41587-019-0252-6"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00109-010-0639-9"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkz569"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1038\/nri2850"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tim.2025.03.002"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.3791\/61715"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.scitotenv.2023.163058"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.3389\/fgene.2022.797420"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.1080\/14634988.2017.1403268"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11160-024-09907-6"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.3390\/ani13182860"},{"key":"e_1_2_11_15_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2105-13-113"},{"key":"e_1_2_11_16_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41587-020-0548-6"},{"key":"e_1_2_11_17_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-025-58080-2"},{"key":"e_1_2_11_18_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12863-022-01067-5"},{"key":"e_1_2_11_19_1","doi-asserted-by":"publisher","DOI":"10.1128\/spectrum.01448-24"},{"key":"e_1_2_11_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1095-8649.2007.01668.x"},{"key":"e_1_2_11_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.foodqual.2022.104732"},{"key":"e_1_2_11_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.aquaculture.2018.06.062"},{"key":"e_1_2_11_23_1","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2018.02000"},{"key":"e_1_2_11_24_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0101357"},{"key":"e_1_2_11_25_1","doi-asserted-by":"publisher","DOI":"10.1186\/s40168-021-01113-x"},{"key":"e_1_2_11_26_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2105-9-559"},{"key":"e_1_2_11_27_1","doi-asserted-by":"publisher","DOI":"10.1093\/femsec\/fiaa255"},{"key":"e_1_2_11_28_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11160-025-10008-1"},{"key":"e_1_2_11_29_1","doi-asserted-by":"publisher","DOI":"10.1007\/s13238-020-00724-8"},{"key":"e_1_2_11_30_1","doi-asserted-by":"publisher","DOI":"10.1139\/gen-2020-0036"},{"key":"e_1_2_11_31_1","doi-asserted-by":"publisher","DOI":"10.3390\/microorganisms11071636"},{"key":"e_1_2_11_32_1","doi-asserted-by":"publisher","DOI":"10.1038\/35016500"},{"key":"e_1_2_11_33_1","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/btu494"},{"key":"e_1_2_11_34_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-024-49098-z"},{"key":"e_1_2_11_35_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.aquaculture.2021.737644"},{"key":"e_1_2_11_36_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0261232"},{"key":"e_1_2_11_37_1","doi-asserted-by":"publisher","DOI":"10.1186\/s42523-025-00461-5"},{"key":"e_1_2_11_38_1","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/bty734"},{"key":"e_1_2_11_39_1","doi-asserted-by":"publisher","DOI":"10.5964\/meth.7769"},{"key":"e_1_2_11_40_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2024.09.019"},{"key":"e_1_2_11_41_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.aquaculture.2022.739121"},{"key":"e_1_2_11_42_1","doi-asserted-by":"publisher","DOI":"10.59120\/drj.v14i2.109"},{"key":"e_1_2_11_43_1","doi-asserted-by":"publisher","DOI":"10.3389\/fmars.2024.1438895"},{"key":"e_1_2_11_44_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.soilbio.2021.108230"},{"key":"e_1_2_11_45_1","doi-asserted-by":"publisher","DOI":"10.3390\/jmse12122275"}],"container-title":["Journal 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