{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T18:46:52Z","timestamp":1790794012722,"version":"4.1.0"},"reference-count":55,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2020,10,12]],"date-time":"2020-10-12T00:00:00Z","timestamp":1602460800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2020,10,12]],"date-time":"2020-10-12T00:00:00Z","timestamp":1602460800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J. Food Biochem."],"published-print":{"date-parts":[[2020,12]]},"DOI":"10.1111\/jfbc.13505","type":"journal-article","created":{"date-parts":[[2020,10,12]],"date-time":"2020-10-12T21:41:35Z","timestamp":1602538895000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":72,"title":["Ferulic acid influences Nrf2 activation to restore testicular tissue from cadmium\u2010induced oxidative challenge, inflammation, and apoptosis in rats"],"prefix":"10.1155","volume":"44","author":[{"given":"Rami B.","family":"Kassab","sequence":"first","affiliation":[{"name":"Department of Zoology and Entomology Faculty of Science Helwan University Cairo Egypt"},{"name":"Department of Biology Faculty of Science and Arts Al Baha University Al Baha Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2830-3479","authenticated-orcid":false,"given":"Maha S.","family":"Lokman","sequence":"additional","affiliation":[{"name":"Biology Department College of Science and Humanities Prince Sattam bin Abdul Aziz University Alkharj Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hamid M. A.","family":"Daabo","sequence":"additional","affiliation":[{"name":"Pharmacy Department Duhok Technical Institute Duhok Polytechnic University Duhok Iraq"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dalia A.","family":"Gaber","sequence":"additional","affiliation":[{"name":"Medical Biochemistry and Molecular Biology Department Faculty of Medicine Helwan University Cairo Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ola A.","family":"Habotta","sequence":"additional","affiliation":[{"name":"Department of Forensic Medicine and Toxicology Faculty of Veterinary Medicine Mansoura University Mansoura Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohamed M.","family":"Hafez","sequence":"additional","affiliation":[{"name":"Biochemistry Department Faculty of Pharmacy Ahram Canadian University (ACU) Giza Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ahmed S.","family":"Zhery","sequence":"additional","affiliation":[{"name":"Kasr Al\u2010Eini School of Medicine Cairo University Cairo Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ahmed E. Abdel","family":"Moneim","sequence":"additional","affiliation":[{"name":"Department of Zoology and Entomology Faculty of Science Helwan University Cairo Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manar S.","family":"Fouda","sequence":"additional","affiliation":[{"name":"Chemistry Department Faculty of Science Helwan University Cairo Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,10,12]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1177\/2156587215621726"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1080\/10942912.2018.1439958"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopha.2018.07.089"},{"issue":"1","key":"e_1_2_10_5_1","doi-asserted-by":"crossref","first-page":"5825","DOI":"10.1038\/s41598-019-42368-7","article-title":"Royal jelly attenuates cadmium\u2010induced nephrotoxicity in male mice","volume":"9","author":"Almeer R. S.","year":"2019","journal-title":"Scientific Reports"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1155\/2018\/8487248"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms19123979"},{"issue":"30","key":"e_1_2_10_8_1","doi-asserted-by":"crossref","first-page":"31254","DOI":"10.1007\/s11356-019-06259-8","article-title":"Possible prophylactic effect of omega\u20103 fatty acids on cadmium\u2010induced neurotoxicity in rats' brains","volume":"26","author":"Alnahdi H. S.","year":"2019","journal-title":"Environmental Science and Pollution Research"},{"issue":"3","key":"e_1_2_10_9_1","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1007\/s00210-019-01736-w","article-title":"Protective effects of vitamin E on cadmium\u2010induced apoptosis in rat testes","volume":"393","author":"Amanpour P.","year":"2019","journal-title":"Naunyn\u2010Schmiedeberg's Archives of Pharmacology"},{"issue":"1","key":"e_1_2_10_10_1","doi-asserted-by":"crossref","first-page":"BSR20180515","DOI":"10.1042\/BSR20180515","article-title":"The molecular and biochemical insight view of grape seed proanthocyanidins in ameliorating cadmium\u2010induced testes\u2010toxicity in rat model: Implication of PI3K\/Akt\/Nrf\u20102 signaling","volume":"39","author":"Bashir N.","year":"2019","journal-title":"Bioscience Reports"},{"issue":"1","key":"e_1_2_10_11_1","first-page":"1","article-title":"Induction of endoplasmic reticulum stress by cadmium and its regulation on Nrf2 signaling pathway in kidneys of rats","volume":"32","author":"Chen Z. J.","year":"2019","journal-title":"Biomedical and Environmental Sciences"},{"key":"e_1_2_10_12_1","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1016\/B978-0-12-405872-9.00002-1","volume-title":"Antioxidants in food, vitamins and supplements","author":"Dasgupta A.","year":"2014"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.lfs.2016.02.004"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/0003-9861(59)90090-6"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms18050957"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11356-017-0873-6"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.273.25.15846"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1439-0272.2012.01279.x"},{"key":"e_1_2_10_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/0003-2697(82)90118-X"},{"key":"e_1_2_10_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tox.2018.11.012"},{"issue":"1","key":"e_1_2_10_21_1","doi-asserted-by":"crossref","DOI":"10.1111\/and.12798","article-title":"Ferulic acid prevents lead\u2010induced testicular oxidative stress and suppressed spermatogenesis in rats","volume":"50","author":"Hasanein P.","year":"2018","journal-title":"Andrologia"},{"key":"e_1_2_10_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.etap.2017.11.002"},{"issue":"2","key":"e_1_2_10_23_1","first-page":"215","article-title":"Human sperm quality and metal toxicants: protective effects of some flavonoids on male reproductive function","volume":"10","author":"Jamalan M.","year":"2016","journal-title":"International Journal of Fertility and Sterility"},{"issue":"2","key":"e_1_2_10_24_1","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1016\/j.toxlet.2010.04.006","article-title":"Cadmium retention increase: A probable key mechanism of the protective effect of zinc on cadmium\u2010induced toxicity in the kidney","volume":"196","author":"Jihen el H.","year":"2010","journal-title":"Toxicology Letters"},{"key":"e_1_2_10_25_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1745-7254.2007.00634.x"},{"key":"e_1_2_10_26_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms20082027"},{"key":"e_1_2_10_27_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11356-019-06099-6"},{"key":"e_1_2_10_28_1","doi-asserted-by":"publisher","DOI":"10.1111\/and.12311"},{"key":"e_1_2_10_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/0041-008X(91)90119-Y"},{"issue":"1","key":"e_1_2_10_30_1","first-page":"225","article-title":"Methyl ferulic acid exerts anti\u2010apoptotic effects on L\u201002 cells via the ROS\u2010mediated signaling pathway","volume":"53","author":"Li L. I.","year":"2018","journal-title":"International Journal of Oncology"},{"key":"e_1_2_10_31_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12011-015-0449-6"},{"key":"e_1_2_10_32_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mad.2019.04.002"},{"key":"e_1_2_10_33_1","doi-asserted-by":"publisher","DOI":"10.3892\/mmr.2016.5218"},{"key":"e_1_2_10_34_1","first-page":"855","volume-title":"Methods of enzymatic analysis","author":"Luck H.","year":"1965"},{"key":"e_1_2_10_35_1","doi-asserted-by":"publisher","DOI":"10.1039\/C9FO00114J"},{"key":"e_1_2_10_36_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejphar.2018.10.003"},{"issue":"1","key":"e_1_2_10_37_1","first-page":"4","article-title":"Oxidative signaling response to cadmium exposure","volume":"156","author":"Nemmiche S.","year":"2016","journal-title":"Toxicological Sciences"},{"key":"e_1_2_10_38_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fct.2011.11.003"},{"key":"e_1_2_10_39_1","doi-asserted-by":"crossref","first-page":"137969","DOI":"10.1016\/j.scitotenv.2020.137969","article-title":"Protocatechuic acid mitigates cadmium\u2010induced neurotoxicity in rats: Role of oxidative stress, inflammation and apoptosis","volume":"723","author":"Olayan A. L.","year":"2020","journal-title":"Science of the Total Environment"},{"key":"e_1_2_10_40_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12011-014-9955-1"},{"key":"e_1_2_10_41_1","doi-asserted-by":"publisher","DOI":"10.1002\/tox.22860"},{"issue":"1","key":"e_1_2_10_42_1","first-page":"158","article-title":"Studies on the quantitative and qualitative characterization of erythrocyte glutathione peroxidase","volume":"70","author":"Paglia D. E.","year":"1967","journal-title":"Journal of Laboratory and Clinical Medicine"},{"key":"e_1_2_10_43_1","doi-asserted-by":"publisher","DOI":"10.4062\/biomolther.2012.093"},{"key":"e_1_2_10_44_1","doi-asserted-by":"publisher","DOI":"10.7314\/APJCP.2012.13.10.5207"},{"key":"e_1_2_10_45_1","doi-asserted-by":"publisher","DOI":"10.1002\/cbf.2983"},{"key":"e_1_2_10_46_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11356-019-05420-7"},{"key":"e_1_2_10_47_1","doi-asserted-by":"publisher","DOI":"10.2147\/DDDT.S198444"},{"key":"e_1_2_10_48_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tox.2007.10.016"},{"key":"e_1_2_10_49_1","doi-asserted-by":"publisher","DOI":"10.1093\/clinchem\/34.3.497"},{"issue":"1","key":"e_1_2_10_50_1","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1186\/s13578-015-0041-y","article-title":"Ferulic acid combined with aspirin demonstrates chemopreventive potential towards pancreatic cancer when delivered using chitosan\u2010coated solid\u2010lipid nanoparticles","volume":"5","author":"Thakkar A.","year":"2015","journal-title":"Cell & Bioscience"},{"key":"e_1_2_10_51_1","doi-asserted-by":"publisher","DOI":"10.2164\/jandrol.108.005132"},{"key":"e_1_2_10_52_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11356-019-07117-3"},{"key":"e_1_2_10_53_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms20030630"},{"key":"e_1_2_10_54_1","first-page":"394632017750518","article-title":"Pretreatment of ferulic acid attenuates inflammation and oxidative stress in a rat model of lipopolysaccharide\u2010induced acute respiratory distress syndrome","volume":"32","author":"Zhang S.","year":"2018","journal-title":"International Journal of Immunopathology and Pharmacology"},{"key":"e_1_2_10_55_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0186727"},{"key":"e_1_2_10_56_1","doi-asserted-by":"publisher","DOI":"10.1093\/jn\/134.11.3083"}],"container-title":["Journal of Food Biochemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jfbc.13505","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/jfbc.13505","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jfbc.13505","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,12,29]],"date-time":"2022-12-29T12:05:20Z","timestamp":1672315520000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/jfbc.13505"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,10,12]]},"references-count":55,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2020,12]]}},"alternative-id":["10.1111\/jfbc.13505"],"URL":"https:\/\/doi.org\/10.1111\/jfbc.13505","archive":["Portico"],"relation":{},"ISSN":["0145-8884","1745-4514"],"issn-type":[{"value":"0145-8884","type":"print"},{"value":"1745-4514","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,10,12]]},"assertion":[{"value":"2020-08-12","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-09-15","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-10-12","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}