{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T12:59:37Z","timestamp":1788872377873,"version":"build-2803163510"},"reference-count":40,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2013,1,9]],"date-time":"2013-01-09T00:00:00Z","timestamp":1357689600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"The Research Council of Norway"},{"name":"The Norwegian Seafood Research Fund","award":["NFR 199778\/S40"],"award-info":[{"award-number":["NFR 199778\/S40"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Fish Diseases"],"published-print":{"date-parts":[[2013,3]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Sea lice on farmed salmonids are often treated with chemicals. Sensitivity testing of sea lice can reduce the number of treatments by identifying substances the sea lice are susceptible to. This study describes a simpler protocol for field sensitivity testing than today's six\u2010dose bioassay. The protocol, which uses a single dose of the delousing agents deltamethrin, azamethiphos and emamectin benzoate, was developed on four different strains of sea lice and their subsequent generations. A sensitive strain and a strain showing reduced sensitivity were identified for each chemical after performing traditional bioassays and small\u2010scale treatments. The single doses for each chemical were established by modelling dose\u2013response curves from 24\u2010h bioassays on strains with differences in sensitivity. The largest difference between the lower 80% prediction interval for the sensitive strain and the upper 80% prediction interval for the strain showing reduced sensitivity was identified for each delousing agent. The concentration of the chemical and the % mortality corresponding to each of the 80% prediction intervals were subsequently established. To validate the protocol for field use, further studies on both sensitive and resistant strains of sea lice under field conditions are required.<\/jats:p>","DOI":"10.1111\/jfd.12053","type":"journal-article","created":{"date-parts":[[2013,1,9]],"date-time":"2013-01-09T13:17:42Z","timestamp":1357737462000},"page":"261-272","source":"Crossref","is-referenced-by-count":41,"title":["Single\u2010dose field bioassay for sensitivity testing in sea lice,\n                    <scp>\n                      <i>L<\/i>\n                    <\/scp>\n                    <i>epeophtheirus salmonis<\/i>\n                    : development of a rapid diagnostic tool"],"prefix":"10.1111","volume":"36","author":[{"given":"K O","family":"Helgesen","sequence":"first","affiliation":[{"name":"Department of Pharmacology and Toxicology Norwegian School of Veterinary Science Oslo Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"T E","family":"Horsberg","sequence":"additional","affiliation":[{"name":"Department of Pharmacology and Toxicology Norwegian School of Veterinary Science Oslo Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2013,1,9]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.aquaculture.2008.11.008"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biocontrol.2003.09.009"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1139\/cjz-76-5-970"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2761.2000.00225.x"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2885.2002.00413.x"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1163\/18759866-0690102015"},{"key":"e_1_2_6_8_1","first-page":"197","article-title":"Sea lice in Chilean salmon farms","volume":"23","author":"Bravo S.","year":"2003","journal-title":"Bulletin of the European Association of Fish Pathologists"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.aquaculture.2008.06.011"},{"key":"e_1_2_6_10_1","first-page":"99","article-title":"Sensitivity assessment in the progeny of Caligus rogercresseyi to emamectin benzoate","volume":"30","author":"Bravo S.","year":"2010","journal-title":"Bulletin of the European Association of Fish Pathologists"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2761.2008.01013.x"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.aquaculture.2010.05.020"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0044-8486(98)00301-9"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1098\/rspb.2009.0771"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2761.2008.01011.x"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1002\/ps.482"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2109.2000.00511.x"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1002\/ps.481"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.3354\/dao060123"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1095-8649.1996.tb01813.x"},{"key":"e_1_2_6_21_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2761.2006.00761.x"},{"key":"e_1_2_6_22_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0025315400051687"},{"key":"e_1_2_6_23_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2761.1992.tb00654.x"},{"key":"e_1_2_6_24_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0001549"},{"key":"e_1_2_6_25_1","doi-asserted-by":"publisher","DOI":"10.1038\/hdy.1982.60"},{"key":"e_1_2_6_26_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2109.2010.02726.x"},{"key":"e_1_2_6_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ecolmodel.2011.03.016"},{"key":"e_1_2_6_28_1","unstructured":"Norwegian Food Safety Authority(2009)Sea lice regulations for aquaculture (Forskrift om bekjempelse av lus i akvakulturanlegg)Paragraph \u00a75. Available athttp:\/\/lovdata.no\/cgi-wift\/wiftldles?doc=\/app\/gratis\/www\/docroot\/for\/sf\/fi\/fi-20090818-1095.html&emne=luseforskrift*& (Accessed June 2012)."},{"key":"e_1_2_6_29_1","unstructured":"Norwegian Food Safety Authority(2011)Regulations for additional requirements for the treatment against sea lice as determined for the first half of 2012 (Forskrift om ytterligere krav til behandling mot lakselus f\u00f8rste halv\u00e5r 2012)Paragraph \u00a73. Available athttp:\/\/lovdata.no\/cgi-wift\/wiftldles?doc=\/app\/gratis\/www\/docroot\/for\/sf\/fi\/fi-20111219-1401.html&emne=lakselus*& (Accessed June 2012)."},{"key":"e_1_2_6_30_1","unstructured":"Norwegian Food Safety Authority(2012)Draft for regulations for suppression of sea lice in aquaculture (Utkast til forskrift om bekjempelse av lakselus i akvakulturanlegg)Paragraph \u00a79 and \u00a710. Available athttp:\/\/www.mattilsynet.no\/mattilsynet\/multimedia\/archive\/00078\/Forslag_til_ny_lakse_78759a.pdf(Accessed June 2012)."},{"key":"e_1_2_6_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0065-308X(08)60233-X"},{"key":"e_1_2_6_32_1","doi-asserted-by":"publisher","DOI":"10.1093\/jee\/88.1.1"},{"key":"e_1_2_6_33_1","doi-asserted-by":"publisher","DOI":"10.1016\/0044-8486(95)01181-1"},{"key":"e_1_2_6_34_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.aquaculture.2006.02.069"},{"key":"e_1_2_6_35_1","doi-asserted-by":"publisher","DOI":"10.1603\/0022-2585(2005)042[0631:DADDFI]2.0.CO;2"},{"key":"e_1_2_6_36_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0044-8486(02)00339-3"},{"key":"e_1_2_6_37_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.aquaculture.2004.11.009"},{"key":"e_1_2_6_38_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.vetpar.2011.03.035"},{"key":"e_1_2_6_39_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2109.2000.00517.x"},{"key":"e_1_2_6_40_1","doi-asserted-by":"publisher","DOI":"10.3354\/dao01887"},{"key":"e_1_2_6_41_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.aquatox.2005.04.007"}],"container-title":["Journal of Fish Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fjfd.12053","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fjfd.12053","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jfd.12053","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,14]],"date-time":"2023-10-14T22:02:03Z","timestamp":1697320923000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/jfd.12053"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,1,9]]},"references-count":40,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2013,3]]}},"alternative-id":["10.1111\/jfd.12053"],"URL":"https:\/\/doi.org\/10.1111\/jfd.12053","archive":["Portico"],"relation":{},"ISSN":["0140-7775","1365-2761"],"issn-type":[{"value":"0140-7775","type":"print"},{"value":"1365-2761","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,1,9]]}}}