{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T18:57:39Z","timestamp":1792695459714,"version":"4.5.0"},"reference-count":49,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2013,10,10]],"date-time":"2013-10-10T00:00:00Z","timestamp":1381363200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"NSRF","award":["09SYN-24-619"],"award-info":[{"award-number":["09SYN-24-619"]}]},{"DOI":"10.13039\/501100004895","name":"European Social Fund","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100004895","id-type":"DOI","asserted-by":"crossref"}]},{"name":"National Strategic Reference Framework"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Fish Diseases"],"published-print":{"date-parts":[[2014,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>A new type of vertebral malformation is described, consisting of deformed cartilaginous neural and haemal processes and the compression and fusion of vertebral bodies. The malformation is designated as haemal vertebral compression and fusion (haemal <jats:styled-content style=\"fixed-case\">VCF<\/jats:styled-content>). We studied the aetiology of the malformations and described microanatomical histopathological alterations. The malformations were detected during routine quality control in one of six monitored Gilthead sea bream populations. Haemal <jats:styled-content style=\"fixed-case\">VCF<\/jats:styled-content> affected the posterior part of the vertebral column (haemal vertebrae). In 20% of the deformed specimens, haemal <jats:styled-content style=\"fixed-case\">VCF<\/jats:styled-content> was combined with lordosis. At 35\u00a0dph (days post\u2010hatching), early anatomical signs of the haemal <jats:styled-content style=\"fixed-case\">VCF<\/jats:styled-content> consisted of abnormal centrum mineralization, malformed cartilaginous neural and haemal processes and developing lordotic alterations. The histological examination of the deformed individuals revealed that haemal <jats:styled-content style=\"fixed-case\">VCF<\/jats:styled-content> is preceded by notochord abnormalities. The frequency of deformed individuals was three times higher at 35 than at 61\u00a0dph (50.3% vs. 17.2%, <jats:italic>n<\/jats:italic>\u00a0=\u00a0157 and <jats:italic>n<\/jats:italic>\u00a0=\u00a0250, respectively). No signs of repair or reversion of malformations have been observed. Thus, the steep decrease in deformities in older animals suggests that haemal <jats:styled-content style=\"fixed-case\">VCF<\/jats:styled-content> is linked to high mortality rates. The results are discussed in respect of the possible causative factors of haemal <jats:styled-content style=\"fixed-case\">VCF<\/jats:styled-content>.<\/jats:p>","DOI":"10.1111\/jfd.12189","type":"journal-article","created":{"date-parts":[[2013,10,12]],"date-time":"2013-10-12T02:30:53Z","timestamp":1381545053000},"page":"949-957","source":"Crossref","is-referenced-by-count":33,"title":["A new type of lordosis and vertebral body compression in <scp>G<\/scp>ilthead sea bream, <i><scp>S<\/scp>parus aurata<\/i> L.: aetiology, anatomy and consequences for survival"],"prefix":"10.1111","volume":"37","author":[{"given":"M","family":"Loizides","sequence":"first","affiliation":[{"name":"Biology Department University of Crete Vasilica Vouton Heraklio Crete Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A N","family":"Georgiou","sequence":"additional","affiliation":[{"name":"Biology Department University of Crete Vasilica Vouton Heraklio Crete Greece"},{"name":"Biology 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