{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,16]],"date-time":"2026-01-16T08:55:24Z","timestamp":1768553724110,"version":"3.49.0"},"reference-count":58,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2016,12,21]],"date-time":"2016-12-21T00:00:00Z","timestamp":1482278400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"Conseller\u00eda de Econom\u00eda e Industria","award":["10MMA020E"],"award-info":[{"award-number":["10MMA020E"]}]},{"name":"Programa de Consolidaci\u00f3n e Estructuraci\u00f3n de Unidades de Investigaci\u00f3n Competitivas","award":["GPC2015\/034"],"award-info":[{"award-number":["GPC2015\/034"]}]},{"name":"Spanish Ministry of Education"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Fish Diseases"],"published-print":{"date-parts":[[2017,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Senegalese sole (<jats:italic>Solea senegalensis<\/jats:italic>, Kaup) is a promising flatfish species in aquaculture. However, skeletal anomalies are still a great concern in sole farming. Investigation of this issue is crucial to improving larval quality and optimizing production. The aim of this study was to thoroughly assess anomalies in the rachis of reared sole at early developmental stages. Sole (<jats:italic>n<\/jats:italic>\u00a0=\u00a0507) were sampled at 31 or 32\u00a0days after hatching (dah). The specimens were stained with alcian blue and alizarin red and evaluated for the detection of vertebral deformities. Most fish presented 9:34:3 vertebrae in abdominal, caudal and caudal complex regions, respectively. Remarkably, all specimens showed at least one spinal anomaly. Alterations of neural\/haemal elements, as well as deformities of hypurals, parhypural and epural, were recurrent. Vertebral body anomalies and\/or vertebral column deviations were identified in 52% of the individuals. Vertebral deformations and fusions were common, especially in caudal complex. \u2018Minor\u2019 anomalies were predominant, and some of the detected disorders might be a result of non\u2010\/low\u2010pathological processes. These results contribute a new insight into the main skeletal anomalies affecting cultured sole larvae. Further research is required to determine their impact on fish welfare and external appearances at commercial stages.<\/jats:p>","DOI":"10.1111\/jfd.12575","type":"journal-article","created":{"date-parts":[[2016,12,21]],"date-time":"2016-12-21T10:26:40Z","timestamp":1482316000000},"page":"987-1000","source":"Crossref","is-referenced-by-count":18,"title":["New insight on vertebral anomalies in cultured Senegalese sole (<i>Solea senegalensis<\/i>, Kaup) at early stages of development"],"prefix":"10.1111","volume":"40","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2451-5039","authenticated-orcid":false,"given":"A M","family":"de Azevedo","sequence":"first","affiliation":[{"name":"Departamento de Anatom\u00eda Producci\u00f3n Animal y Ciencias Cl\u00ednicas Veterinarias Facultade de Veterinaria Universidade de Santiago de Compostela Lugo Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A 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