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The populations were geographically isolated, of distinct origins, and did not share water sources. Affected fish showed various external (e.g., exophthalmia and cachexia, among others) and internal (e.g., granulomatous septicaemia and interstitial nephritis, among others) signs. All internal organ samples produced pure cultures, two of which (one from each farm, termed S\u20101 and S\u20102) were subjected to biochemical, <jats:styled-content style=\"fixed-case\">PCR<\/jats:styled-content> and 16S <jats:styled-content style=\"fixed-case\">rRNA<\/jats:styled-content> sequencing (99.5% similarity) analyses, confirming <jats:italic>S.\u00a0iniae<\/jats:italic> identification. The two isolates presented genetic homogeneity regardless of technique (i.e., <jats:styled-content style=\"fixed-case\">RAPD<\/jats:styled-content>,<jats:styled-content style=\"fixed-case\"> REP<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">PCR<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">ERIC<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">PCR<\/jats:styled-content> analyses). Pathogenic potentials were assessed through intraperitoneal injection challenges in rainbow trout (<jats:italic>Oncorhynchus mykiss<\/jats:italic>) and zebrafish (<jats:italic>Danio rerio<\/jats:italic>). Rainbow trout mortalities were respectively 40% and 70% at 10<jats:sup>4<\/jats:sup> and 10<jats:sup>6<\/jats:sup>\u00a0<jats:styled-content style=\"fixed-case\">CFU<\/jats:styled-content> per fish with the S\u20101 isolate, while 100% mortality rates were recorded in zebrafish at 10<jats:sup>2<\/jats:sup> and 10<jats:sup>4<\/jats:sup>\u00a0<jats:styled-content style=\"fixed-case\">CFU<\/jats:styled-content> per fish with the S\u20102 isolate. The obtained data clearly indicate a relationship between intensified aquaculture activities in Mexico and new disease appearances. Future studies should establish clinical significances for the tilapia industry.<\/jats:p>","DOI":"10.1111\/jfd.12775","type":"journal-article","created":{"date-parts":[[2018,1,10]],"date-time":"2018-01-10T12:26:04Z","timestamp":1515587164000},"page":"773-782","source":"Crossref","is-referenced-by-count":43,"title":["First identification and characterization of <i>Streptococcus iniae<\/i> obtained from tilapia (<i>Oreochromis aureus<\/i>) farmed in Mexico"],"prefix":"10.1111","volume":"41","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4995-4676","authenticated-orcid":false,"given":"C","family":"Ortega","sequence":"first","affiliation":[{"name":"Centro de Investigaci\u00f3n y Estudios Avanzados en Salud Animal (CIESA) Facultad de Medicina Veterinaria y Zootecnia (FMVZ) Universidad Aut\u00f3noma del Estado de M\u00e9xico (UAEM) Toluca M\u00e9xico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"I","family":"Garc\u00eda","sequence":"additional","affiliation":[{"name":"Centro de Investigaci\u00f3n y Estudios Avanzados en Salud Animal (CIESA) Facultad de Medicina Veterinaria y Zootecnia (FMVZ) Universidad Aut\u00f3noma del Estado de M\u00e9xico (UAEM) Toluca M\u00e9xico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R","family":"Irgang","sequence":"additional","affiliation":[{"name":"Universidad Andr\u00e9s Bello Laboratorio de Patolog\u00eda de Organismos Acu\u00e1ticos y Biotecnolog\u00eda Acu\u00edcola Facultad de Ciencias Biol\u00f3gicas Vi\u00f1a del Mar Chile"},{"name":"Centro FONDAP Interdisciplinary Center for Aquaculture Research (INCAR) Concepci\u00f3n Chile"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R","family":"Fajardo","sequence":"additional","affiliation":[{"name":"Centro de Investigaci\u00f3n y Estudios Avanzados en Salud Animal (CIESA) Facultad de Medicina Veterinaria y Zootecnia (FMVZ) Universidad Aut\u00f3noma del Estado de M\u00e9xico (UAEM) Toluca M\u00e9xico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D","family":"Tapia\u2010Cammas","sequence":"additional","affiliation":[{"name":"Universidad Andr\u00e9s Bello Laboratorio de Patolog\u00eda de Organismos Acu\u00e1ticos y Biotecnolog\u00eda Acu\u00edcola Facultad de Ciencias Biol\u00f3gicas Vi\u00f1a del Mar Chile"},{"name":"Centro FONDAP Interdisciplinary Center for Aquaculture Research (INCAR) Concepci\u00f3n Chile"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J","family":"Acosta","sequence":"additional","affiliation":[{"name":"Centro de Investigaci\u00f3n y Estudios Avanzados en Salud Animal (CIESA) Facultad de Medicina Veterinaria y Zootecnia (FMVZ) Universidad Aut\u00f3noma del Estado de M\u00e9xico (UAEM) Toluca M\u00e9xico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5368-4475","authenticated-orcid":false,"given":"R","family":"Avenda\u00f1o\u2010Herrera","sequence":"additional","affiliation":[{"name":"Universidad Andr\u00e9s Bello Laboratorio de Patolog\u00eda de Organismos Acu\u00e1ticos y Biotecnolog\u00eda Acu\u00edcola Facultad de Ciencias Biol\u00f3gicas Vi\u00f1a del Mar Chile"},{"name":"Centro FONDAP Interdisciplinary Center for Aquaculture Research (INCAR) Concepci\u00f3n Chile"},{"name":"Centro de Investigaci\u00f3n Marina Quintay (CIMARQ) Universidad Andr\u00e9s Bello Quintay Chile"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2018,1,9]]},"reference":[{"key":"e_1_2_5_2_1","first-page":"132","article-title":"Some histopathological aspects of streptococcosis in cultured rainbow trout (Oncorhynchus mykiss)","volume":"24","author":"Akhlaghi M.","year":"2004","journal-title":"Bulletin\u2010European Association of Fish Pathologists"},{"key":"e_1_2_5_3_1","first-page":"195","article-title":"Streptococcosis in tilapia (Oreochromis niloticus): A review","volume":"34","author":"Amal M. 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