{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T10:25:51Z","timestamp":1760955951273,"version":"3.37.3"},"reference-count":27,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2019,6,11]],"date-time":"2019-06-11T00:00:00Z","timestamp":1560211200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100007465","name":"UiT-The Arctic University of Norway","doi-asserted-by":"crossref","id":[{"id":"10.13039\/100007465","id-type":"DOI","asserted-by":"crossref"}]},{"name":"PHARMAQ AS"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Fish Diseases"],"published-print":{"date-parts":[[2019,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>In today's aquaculture of Atlantic salmon (<jats:italic>Salmo salar<\/jats:italic> L.), a majority of viral disease outbreaks occur after seawater transfer. A relevant question is how the parr\u2013smolt transformation influences the efficacy of viral vaccines and the innate resistance against viral diseases. In this study, vaccinated and unvaccinated A. salmon parr were exposed to different photoperiodic regimens (1\u2010, 3\u2010 or 6\u2010week continuous light\u2014WCL). Fish groups at different stages in the smoltification process were induced, as demonstrated by differences in morphological and physiological smolt parameters. At the time of seawater transfer, the 6\u2010WCL group had reached a more pronounced stage in the smoltification process than the 1\u2010WCL group. In unvaccinated fish, the subsequent cohabitation challenge with infectious pancreatic necrosis virus (IPNV) gave a significantly higher accumulated mortality in the 6\u2010WCL group (87%) compared to the 1\u2010WCL group (39%). In the vaccinated groups, this effect was not apparent and there were no differences in accumulated mortality between the 1 WCL, 3 WCL and 6\u2010WCL groups. These data suggest that the resistance to IPN in A. salmon was negatively influenced by smoltification, while vaccine\u2010mediated protection to IPN was maintained equally well irrespective of smolt status.<\/jats:p>","DOI":"10.1111\/jfd.13049","type":"journal-article","created":{"date-parts":[[2019,6,18]],"date-time":"2019-06-18T12:37:31Z","timestamp":1560861451000},"page":"1271-1282","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Differences in smolt status affect the resistance of Atlantic salmon (<i>Salmo salar <\/i>L.) against infectious pancreatic necrosis, while vaccine\u2010mediated protection is unaffected"],"prefix":"10.1111","volume":"42","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5984-3326","authenticated-orcid":false,"given":"Ingvill","family":"Jensen","sequence":"first","affiliation":[{"name":"Faculty of Biosciences, Fisheries and Economics, Norwegian College of Fishery Science UiT The Arctic University of Norway Troms\u00f8 Norway"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mathias C.","family":"Overrein","sequence":"additional","affiliation":[{"name":"Faculty of Biosciences, Fisheries and Economics, Norwegian College of Fishery Science UiT The Arctic University of Norway Troms\u00f8 Norway"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B\u00f8rge N.","family":"Fredriksen","sequence":"additional","affiliation":[{"name":"PHARMAQ AS Oslo Norway"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guro","family":"Strandskog","sequence":"additional","affiliation":[{"name":"Faculty of Biosciences, Fisheries and Economics, Norwegian College of Fishery Science UiT The Arctic University of Norway Troms\u00f8 Norway"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5010-5095","authenticated-orcid":false,"given":"Tore","family":"Seternes","sequence":"additional","affiliation":[{"name":"Faculty of Biosciences, Fisheries and Economics, Norwegian College of Fishery Science UiT The Arctic University of Norway Troms\u00f8 Norway"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2019,6,18]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ygcen.2010.07.003"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/0044-8486(94)90013-2"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0044-8486(97)00178-6"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1177\/104063879000200406"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fsi.2012.01.004"},{"key":"e_1_2_7_7_1","unstructured":"Hjeltnes B. Bang\u2010Jensen B. Born\u00f8 G. Haukaas A. &Walde C.(2018).Fiskehelserapporten 2017. Report: The Norwegian Veterinary Institute.https:\/\/www.vetinst.no\/rapporter-ogpublikasjoner\/rapporter\/2018\/fiskehelserapporten-2017"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.molimm.2016.04.007"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.aquaculture.2009.02.002"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fsi.2016.09.026"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jviromet.2009.07.003"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0044-8486(03)00032-2"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1006\/meth.2001.1262"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1139\/f93-075"},{"key":"e_1_2_7_15_1","first-page":"199","volume-title":"Euryhaline fishes","author":"McCormick S. 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