{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T12:27:28Z","timestamp":1753878448332,"version":"3.41.2"},"reference-count":11,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2024,9,9]],"date-time":"2024-09-09T00:00:00Z","timestamp":1725840000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100001871","name":"Funda\u00e7\u00e3o para a Ci\u00eancia e a Tecnologia","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001871","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Fish Diseases"],"published-print":{"date-parts":[[2024,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Thyroid tissue in teleosts is located mainly in the pharyngeal region, usually reaching other adjacent anatomical locations. Herein, a nodular lesion located in the left operculum of a Senegal seabream (<jats:italic>Diplodus bellottii<\/jats:italic>) was surgically excised and sent for microscopical evaluation. Microscopically, the lesion presented irregular borders and consisted in columnar epithelial cells arranged in a tubulopapillary pattern, surrounding a central lumen filled with acellular, acidophilic and homogeneous, material (\u2018colloid\u2019). To determine the lesion's histogenesis, immunohistochemistry was performed employing antibodies for AE1\/AE3, CK7, thyroglobulin and vimentin. The neoplastic cells presented low mitotic index and positive immunolabelling for CK7 and thyroglobulin. Therefore, a diagnosis of ectopic thyroid adenoma was made. Herein, the successful employment of antibodies classically used in mammals for accurate diagnosis of thyroid disorders is described. Proliferation of thyroid tissue in fish may reflect environmental and physiological imbalances, making the study and correct diagnosis of these tumours in this species important.<\/jats:p>","DOI":"10.1111\/jfd.14015","type":"journal-article","created":{"date-parts":[[2024,9,9]],"date-time":"2024-09-09T13:01:22Z","timestamp":1725886882000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Ectopic thyroid adenoma diagnosed in a Senegal seabream (<i>Diplodus bellottii<\/i>, Steindachner 1882): Towards an accurate diagnosis"],"prefix":"10.1111","volume":"47","author":[{"given":"Gabriela Fernandes","family":"da Silva","sequence":"first","affiliation":[{"name":"School of Medicine and Biomedical Sciences (ICBAS) University of Porto  Porto Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F\u00e1tima","family":"Faria","sequence":"additional","affiliation":[{"name":"School of Medicine and Biomedical Sciences (ICBAS) University of Porto  Porto Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F\u00e1tima","family":"Gil","sequence":"additional","affiliation":[{"name":"Aqu\u00e1rio Vasco da Gama  Cruz Quebrada\u2013Dafundo Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nuno","family":"Leit\u00e3o","sequence":"additional","affiliation":[{"name":"Aqu\u00e1rio Vasco da Gama  Cruz Quebrada\u2013Dafundo Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paulo","family":"Ribeiro","sequence":"additional","affiliation":[{"name":"Aqu\u00e1rio Vasco da Gama  Cruz Quebrada\u2013Dafundo Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katia","family":"Pinello","sequence":"additional","affiliation":[{"name":"School of Medicine and Biomedical Sciences (ICBAS) University of Porto  Porto Portugal"},{"name":"EPIUnit\u2010Instituto de Sa\u00fade P\u00fablica, ISPUP Universidade do Porto  Porto Portugal"},{"name":"Laborat\u00f3rio para a Investiga\u00e7\u00e3o Integrativa e Translacional em Sa\u00fade Populacional (ITR)  Porto Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jo\u00e3o","family":"Niza\u2010Ribeiro","sequence":"additional","affiliation":[{"name":"School of Medicine and Biomedical Sciences (ICBAS) University of Porto  Porto Portugal"},{"name":"EPIUnit\u2010Instituto de Sa\u00fade P\u00fablica, ISPUP Universidade do Porto  Porto Portugal"},{"name":"Laborat\u00f3rio para a Investiga\u00e7\u00e3o Integrativa e Translacional em Sa\u00fade Populacional (ITR)  Porto Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2305-1631","authenticated-orcid":false,"given":"Irina","family":"Amorim","sequence":"additional","affiliation":[{"name":"School of Medicine and Biomedical Sciences (ICBAS) University of Porto  Porto Portugal"},{"name":"Institute for Research and Innovation in Health (i3S) University of Porto  Porto Portugal"},{"name":"Institute of Molecular Pathology and Immunology of the University of Porto (IPATIMUP)  Porto Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,9,9]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.3390\/ani13182934"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/00129039\u2010200009000\u201000004"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1080\/10408440601123529"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.3390\/ani14030464"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1080\/01926230500214509"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cvex.2004.04.012"},{"key":"e_1_2_7_8_1","first-page":"1","article-title":"Reflections on the thyroidology of fishes: From molecules to humankind","volume":"2","author":"Leatherland J. 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Retrieved February 20 2024.10.14284\/170."}],"container-title":["Journal of Fish Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jfd.14015","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,11,9]],"date-time":"2024-11-09T03:53:00Z","timestamp":1731124380000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/jfd.14015"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,9,9]]},"references-count":11,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2024,12]]}},"alternative-id":["10.1111\/jfd.14015"],"URL":"https:\/\/doi.org\/10.1111\/jfd.14015","archive":["Portico"],"relation":{},"ISSN":["0140-7775","1365-2761"],"issn-type":[{"type":"print","value":"0140-7775"},{"type":"electronic","value":"1365-2761"}],"subject":[],"published":{"date-parts":[[2024,9,9]]},"assertion":[{"value":"2024-04-05","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-08-21","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-09-09","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e14015"}}