{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T22:53:45Z","timestamp":1789772025153,"version":"4.0.1"},"reference-count":46,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2024,10,29]],"date-time":"2024-10-29T00:00:00Z","timestamp":1730160000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Fish Diseases"],"published-print":{"date-parts":[[2025,1]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:p>The objective of this study was to evaluate the effect of dietary supplementation with <jats:italic>Citrus sinensis<\/jats:italic> (L.) Osbeck essential oil on the growth, immune system, and resistance to <jats:italic>Aeromonas hydrophila<\/jats:italic> infection in <jats:italic>Colossoma macropomum<\/jats:italic> fingerlings. The experiment was conducted with five treatments (control diet, Tween80 diet, and diets supplemented with 200, 400, and 800\u2009mg\u2009L<jats:sup>\u22121<\/jats:sup> of <jats:italic>C. sinensis<\/jats:italic> essential oil) with four replicates. At the end of the experimental period, growth parameters were measured, and blood samples were collected for thrombogram, leukogram, and phagocytic activity analysis. A bacterial challenge with <jats:italic>A. hydrophila<\/jats:italic> was conducted for 96\u2009h. <jats:italic>C. macropomum<\/jats:italic> fingerlings that were fed with 400 and 800\u2009mg\u2009L<jats:sup>\u22121<\/jats:sup> of <jats:italic>C. sinensis<\/jats:italic> essential oil had the highest growth parameters, with final weights of 533.18\u2009\u00b1\u20092.03\u2009mg and 531.91\u2009\u00b1\u20092.67\u2009mg, respectively, and an increase in the number of thrombocytes, lymphocytes, monocytes, and neutrophils, as well as higher phagocytosis rates compared to the control group. Regarding the challenge, fish in the 400 and 800\u2009mg\u2009L<jats:sup>\u22121<\/jats:sup> treatments also exhibited the lowest cumulative mortality rate (26.66%\u2009\u00b1\u20093.33%). Therefore, supplementation with <jats:italic>C. sinensis<\/jats:italic> essential oil promotes growth, improves health, and enhances resistance to <jats:italic>A. hydrophila<\/jats:italic> in <jats:italic>C. macropomum<\/jats:italic> fingerlings.<\/jats:p>","DOI":"10.1111\/jfd.14039","type":"journal-article","created":{"date-parts":[[2024,10,29]],"date-time":"2024-10-29T12:21:52Z","timestamp":1730204512000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Enriched Diet With Orange Essential Oil <i>Citrus sinensis<\/i> for Tambaqui <i>Colossoma macropomum<\/i> Promotes Growth Performance and Resistance Against <i>Aeromonas hydrophila<\/i>"],"prefix":"10.1111","volume":"48","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6505-5676","authenticated-orcid":false,"given":"Jucimauro de Ara\u00fajo","family":"Pereira J\u00fanior","sequence":"first","affiliation":[{"name":"Aquaculture Department AQUOS: Aquatic Organisms 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