{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,11]],"date-time":"2026-06-11T15:59:18Z","timestamp":1781193558641,"version":"3.54.1"},"reference-count":30,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2025,12,22]],"date-time":"2025-12-22T00:00:00Z","timestamp":1766361600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,12,22]],"date-time":"2025-12-22T00:00:00Z","timestamp":1766361600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100003593","name":"Conselho Nacional de Desenvolvimento Cient\u00edfico e Tecnol\u00f3gico","doi-asserted-by":"publisher","award":["301911\/2022\u20103"],"award-info":[{"award-number":["301911\/2022\u20103"]}],"id":[{"id":"10.13039\/501100003593","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Fish Diseases"],"published-print":{"date-parts":[[2026,6]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    Intensification of fish aquaculture worldwide has led to severe problems of diseases caused by parasitic dactylogyrideans. In this study, the anti\u2010dactylogyridean efficacy of treating\n                    <jats:styled-content style=\"fixed-case\">\n                      <jats:italic>Colossoma macropomum<\/jats:italic>\n                    <\/jats:styled-content>\n                    with baths of emamectin benzoate (EMB) was investigated for the first time, along with the effects of this treatment on the haematology and histology of its gills. Thirty\u2010nine fish (three replicates of 13 each) received four consecutive daily baths with EMB at a concentration of 0.5\u2009g\u2009L\n                    <jats:sup>\u22121<\/jats:sup>\n                    and one control group of 39 fish (three replicates of 13 each) only received water from the cultivation tank. The EMB treatments showed effectiveness of 50.2% against\n                    <jats:italic>Anacanthorus spathulatus, Notozothecium janauachensis<\/jats:italic>\n                    and\n                    <jats:italic>Mymarothecium boegeri<\/jats:italic>\n                    infecting the gills of\n                    <jats:styled-content style=\"fixed-case\">\n                      <jats:italic>C. macropomum<\/jats:italic>\n                    <\/jats:styled-content>\n                    . Fish treated with EMB only caused decreases in the total red blood cell, total thrombocytes, leukocytes, monocytes and neutrophils numbers, while the mean corpuscular haemoglobin concentration (MCHC) increased. Aneurysm was the gill structural alteration caused by EMB treatment, and mean assessment values (MAV) indicated moderate to severe damage due to this irreversible gill alteration. Our results lay a safe foundation for the application of EMB as a potential chemotherapeutic agent for dactylogyridean control in\n                    <jats:styled-content style=\"fixed-case\">\n                      <jats:italic>C. macropomum<\/jats:italic>\n                    <\/jats:styled-content>\n                    aquaculture, because this drug should be used cautiously for anthelminthic treatment in fish.\n                  <\/jats:p>","DOI":"10.1111\/jfd.70090","type":"journal-article","created":{"date-parts":[[2025,12,22]],"date-time":"2025-12-22T11:06:25Z","timestamp":1766401585000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Bath Treatments With Emamectin Benzoate Control Dactylogyrideans Infecting\n                    <i>Colossoma macropomum<\/i>\n                    Gills Without Altering Physiology of This Host Fish"],"prefix":"10.1111","volume":"49","author":[{"given":"Raimundo Rosemiro de Jesus","family":"Baia","sequence":"first","affiliation":[{"name":"Programa de P\u00f3s\u2010Gradua\u00e7\u00e3o Em Biodiversidade Tropical (PPGBIO) Universidade Federal do Amap\u00e1 (UNIFAP)  Macap\u00e1 Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcela Nunes","family":"Videira","sequence":"additional","affiliation":[{"name":"Laborat\u00f3rio de Morfofisiologia e Sanidade Animal Universidade do Estado do Amap\u00e1 (UEAP)  Macap\u00e1 Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amanda Mendes","family":"Pacheco","sequence":"additional","affiliation":[{"name":"Embrapa Amap\u00e1  Macap\u00e1 Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eliane Tie Oba","family":"Yoshioka","sequence":"additional","affiliation":[{"name":"Programa de P\u00f3s\u2010Gradua\u00e7\u00e3o Em Biodiversidade Tropical (PPGBIO) Universidade Federal do Amap\u00e1 (UNIFAP)  Macap\u00e1 Brazil"},{"name":"Embrapa Amap\u00e1  Macap\u00e1 Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8376-1846","authenticated-orcid":false,"given":"Marcos","family":"Tavares\u2010Dias","sequence":"additional","affiliation":[{"name":"Programa de P\u00f3s\u2010Gradua\u00e7\u00e3o Em Biodiversidade Tropical (PPGBIO) Universidade Federal do Amap\u00e1 (UNIFAP)  Macap\u00e1 Brazil"},{"name":"Embrapa Amap\u00e1  Macap\u00e1 Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,12,22]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.eas.2024.100042"},{"key":"e_1_2_12_3_1","doi-asserted-by":"publisher","DOI":"10.20935\/AcadBiol7540"},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/jfd.12952"},{"key":"e_1_2_12_5_1","doi-asserted-by":"publisher","DOI":"10.1080\/10454438.2024.2419843"},{"key":"e_1_2_12_6_1","doi-asserted-by":"publisher","DOI":"10.1590\/1678\u20104162\u201013036"},{"key":"e_1_2_12_7_1","doi-asserted-by":"publisher","DOI":"10.2307\/3284227"},{"key":"e_1_2_12_8_1","doi-asserted-by":"publisher","DOI":"10.1089\/zeb.2014.1021"},{"key":"e_1_2_12_9_1","doi-asserted-by":"publisher","DOI":"10.1080\/03601234.2023.2232274"},{"key":"e_1_2_12_10_1","volume-title":"M\u00e9todos de estudo e t\u00e9cnicas laboratoriais em Parasitologia de Peixes","author":"Eiras J. C.","year":"2006"},{"key":"e_1_2_12_11_1","doi-asserted-by":"crossref","unstructured":"FAO.2024.\u201cThe State of World Fisheries and Aquaculture 2024 \u2013 Blue Transformation in Action \u201d Rome.https:\/\/doi.org\/10.4060\/cd0683en.","DOI":"10.4060\/cd0683en"},{"key":"e_1_2_12_12_1","volume-title":"An R Companion to Applied Regression [online]","author":"Fox J.","year":"2019"},{"key":"e_1_2_12_13_1","unstructured":"Herve M.2023.\u201cRVAideMemoire: Testing and Plotting Procedures for Biostatistics \u201d R package version 0.9\u201382\u20102 [online][cited 2025 October 1].https:\/\/CRAN.R\u2010project.org\/package=RVAideMemoire."},{"key":"e_1_2_12_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.etap.2020.103348"},{"key":"e_1_2_12_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/jfd.13057"},{"key":"e_1_2_12_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.toxrep.2022.01.001"},{"key":"e_1_2_12_17_1","doi-asserted-by":"publisher","DOI":"10.3390\/parasitologia3020021"},{"key":"e_1_2_12_18_1","doi-asserted-by":"publisher","DOI":"10.3389\/fphar.2023.1106124"},{"key":"e_1_2_12_19_1","doi-asserted-by":"publisher","DOI":"10.1155\/2024\/5515748"},{"key":"e_1_2_12_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/raq.12839"},{"key":"e_1_2_12_21_1","doi-asserted-by":"publisher","DOI":"10.1111\/jfd.12980"},{"key":"e_1_2_12_22_1","first-page":"339","volume-title":"Sublethal and Chronic Effects of Pollutants on Freshwater Fish","author":"Poleksi\u0107 V.","year":"1994"},{"key":"e_1_2_12_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.aquaculture.2022.737940"},{"key":"e_1_2_12_24_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12639\u2010023\u201001571\u20100"},{"key":"e_1_2_12_25_1","doi-asserted-by":"publisher","DOI":"10.7476\/9788576286530"},{"key":"e_1_2_12_26_1","doi-asserted-by":"publisher","DOI":"10.3354\/dao02303"},{"key":"e_1_2_12_27_1","doi-asserted-by":"publisher","DOI":"10.1023\/A:1008212000208"},{"key":"e_1_2_12_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.vetpar.2015.11.003"},{"key":"e_1_2_12_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.vetpar.2025.110401"},{"key":"e_1_2_12_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.vetpar.2008.07.034"},{"key":"e_1_2_12_31_1","doi-asserted-by":"publisher","DOI":"10.2478\/helm\u20102023\u20100019"}],"container-title":["Journal of Fish Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jfd.70090","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/jfd.70090","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jfd.70090","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,6,11]],"date-time":"2026-06-11T15:22:11Z","timestamp":1781191331000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/jfd.70090"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,12,22]]},"references-count":30,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2026,6]]}},"alternative-id":["10.1111\/jfd.70090"],"URL":"https:\/\/doi.org\/10.1111\/jfd.70090","archive":["Portico"],"relation":{},"ISSN":["0140-7775","1365-2761"],"issn-type":[{"value":"0140-7775","type":"print"},{"value":"1365-2761","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,12,22]]},"assertion":[{"value":"2025-10-14","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-11-15","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-12-22","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70090"}}