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However, the susceptibility of the Ezo abalone,\n                    <jats:italic>\n                      <jats:styled-content style=\"fixed-case\">H. discus hannai<\/jats:styled-content>\n                      ,\n                    <\/jats:italic>\n                    to the virus has not been investigated, unlike the other commercially important\n                    <jats:italic>Haliotis<\/jats:italic>\n                    species in Japan. In this study,\n                    <jats:styled-content style=\"fixed-case\">\n                      <jats:italic>H. discus hannai<\/jats:italic>\n                    <\/jats:styled-content>\n                    at 6\u2009months of age were exposed to effluent from an aquarium containing AbALV\u2010infected\n                    <jats:styled-content style=\"fixed-case\">\n                      <jats:italic>H. discus discus<\/jats:italic>\n                    <\/jats:styled-content>\n                    and monitored for 49\u2009days. The mortality rate began to increase at approximately 40\u2009days post\u2010infection (dpi). The cumulative mortality was significantly higher in the infected group (45% \u2013 55%) than in the uninfected control group (14% \u2013 15%) at the end of the experiment. The mean viral load peaked at 10\n                    <jats:sup>5.4 \u00b1 0.4<\/jats:sup>\n                    copies\/\u03bcg total DNA at 29 dpi. Histological analysis detected many degenerated cells in the gills at 29 dpi, and these cells were immunohistochemically positive for AbALV. Although the number of degenerated cells decreased thereafter, oedema became remarkable in the gills at 42 and 49 dpi, which may have contributed to high mortality in juveniles. Our study suggests that infection control against AbALV is essential for stable juvenile production of\n                    <jats:styled-content style=\"fixed-case\">\n                      <jats:italic>H. discus hannai<\/jats:italic>\n                    <\/jats:styled-content>\n                    , similar to that of other susceptible\n                    <jats:italic>Haliotis<\/jats:italic>\n                    species\/subspecies.\n                  <\/jats:p>","DOI":"10.1111\/jfd.70113","type":"journal-article","created":{"date-parts":[[2026,1,2]],"date-time":"2026-01-02T09:30:47Z","timestamp":1767346247000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Susceptibility of Ezo Abalone\n                    <i>Haliotis discus hannai<\/i>\n                    to Abalone Asfa\u2010Like Virus (AbALV) Infection"],"prefix":"10.1111","volume":"49","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6550-6852","authenticated-orcid":false,"given":"Kousuke","family":"Umeda","sequence":"first","affiliation":[{"name":"Pathology Division, Aquaculture Research Department Fisheries Technology Institute, Japan Fisheries Research and Education Agency  Minami\u2010ise Mie Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ikunari","family":"Kiryu","sequence":"additional","affiliation":[{"name":"Pathology Division, Aquaculture Research Department Fisheries Technology Institute, Japan Fisheries Research and Education Agency  Tamaki Mie Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takuya","family":"Kawashima","sequence":"additional","affiliation":[{"name":"Aquaculture Division Iwate Fisheries Technology Center  Iwate Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Toshimasa","family":"Kobayashi","sequence":"additional","affiliation":[{"name":"Iwate Inland Fisheries Technology Center  Iwate Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9520-8263","authenticated-orcid":false,"given":"Tomomasa","family":"Matsuyama","sequence":"additional","affiliation":[{"name":"Pathology Division, Aquaculture Research Department Fisheries Technology Institute, Japan Fisheries Research and Education Agency  Minami\u2010ise Mie Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,1,2]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.3147\/jsfp.57.30"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1080\/00288330.2023.2261869"},{"key":"e_1_2_10_4_1","unstructured":"Goto H. 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