{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,4]],"date-time":"2026-06-04T15:11:33Z","timestamp":1780585893114,"version":"3.54.1"},"reference-count":51,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2026,2,7]],"date-time":"2026-02-07T00:00:00Z","timestamp":1770422400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,2,7]],"date-time":"2026-02-07T00:00:00Z","timestamp":1770422400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100000041","name":"Fisheries and Oceans Canada","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000041","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Fish Diseases"],"published-print":{"date-parts":[[2026,7]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    Infectious salmon anaemia virus (ISAV) can cause disease and mortality in Atlantic salmon (\n                    <jats:styled-content style=\"fixed-case\">\n                      <jats:italic>Salmo salar<\/jats:italic>\n                    <\/jats:styled-content>\n                    ). The virus is endemic in several regions including the Atlantic coast of Canada. Lumpfish (\n                    <jats:styled-content style=\"fixed-case\">\n                      <jats:italic>Cyclopterus lumpus<\/jats:italic>\n                    <\/jats:styled-content>\n                    ) are increasingly utilised as cleaner fish to control sea lice levels in Atlantic salmon farms. With welfare concerns for both species, and the possibility of escaped fish, the objective of this study was to determine the susceptibility of lumpfish to ISAV. Lumpfish were exposed to two ISAV isolates (high and low virulence) through a cohabitation challenge (i.e., exposure to infected salmon) and through an intra\u2010peritoneal challenge. Na\u00efve salmon were exposed simultaneously to the same isolates tested to verify their virulence. In the cohabitation challenge, ISAV infection progressed as expected in the na\u00efve salmon. ISAV was detected in a small number of lumpfish gill samples, but the lack of detection in other organs, e.g., heart, kidney, spleen, liver, and blood, suggests environmental contamination. Although two lumpfish blood samples tested positive in the later stages of the challenge, all other disease indicators, including a lack of anaemia, did not support potential for virus replication in lumpfish. Based on both exposure experiments, lumpfish do not appear to be susceptible to ISAV.\n                  <\/jats:p>","DOI":"10.1111\/jfd.70141","type":"journal-article","created":{"date-parts":[[2026,2,8]],"date-time":"2026-02-08T00:45:31Z","timestamp":1770511531000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Lack of Lumpfish (\n                    <scp>\n                      <i>Cyclopterus lumpus<\/i>\n                    <\/scp>\n                    ) Susceptibility to the Infectious Salmon Anaemia Virus (\n                    <scp>ISAV<\/scp>\n                    ) Using In\u00a0Vivo Challenges"],"prefix":"10.1111","volume":"49","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7739-0735","authenticated-orcid":false,"given":"Nellie","family":"Gagn\u00e9","sequence":"first","affiliation":[{"name":"Fisheries &amp; Oceans Canada Gulf Fisheries Centre  Moncton New Brunswick Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8980-1618","authenticated-orcid":false,"given":"Delphine","family":"Ditlecadet","sequence":"additional","affiliation":[{"name":"Fisheries &amp; Oceans Canada Gulf Fisheries Centre  Moncton New Brunswick Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kristine","family":"H\u00e9bert","sequence":"additional","affiliation":[{"name":"Fisheries &amp; Oceans Canada Gulf Fisheries Centre  Moncton New Brunswick Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chantal","family":"Audet","sequence":"additional","affiliation":[{"name":"Fisheries &amp; Oceans Canada Gulf Fisheries Centre  Moncton New Brunswick Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Steven","family":"Leadbeater","sequence":"additional","affiliation":[{"name":"Fisheries &amp; Oceans Canada St. Andrews Biological Station  St. Andrews New Brunswick Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew K.","family":"Swanson","sequence":"additional","affiliation":[{"name":"Cooke Aquaculture Inc.  Saint John New Brunswick Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,2,7]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/jfd.12225"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/jfd.12284"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.00047\u201012"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0209178"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/raq.12456"},{"key":"e_1_2_11_7_1","unstructured":"Bjordal A.1990.\u201cSea Lice Infestation on Farmed Salmon: Possible Use of Cleaner Fish as an Alternative Method for Delousing.\u201dIn Canada\u2010Norway Finfish Aquaculture Workshop St\u2010Andrews NB September 10\u201314 1989 (pp. 85\u201389). Canadian Technical Report of Fisheries and Aquatic Science 1761."},{"key":"e_1_2_11_8_1","first-page":"350","volume-title":"Fish Parasites: Pathobiology and Protection","author":"Burka J. F.","year":"2011"},{"key":"e_1_2_11_9_1","volume-title":"A Review of Potential Environmental Risks Associated With the Use of Pesticides to Treat Atlantic Salmon Against Infestations of Sea Lice in Canada","author":"Burridge L. 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