{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,5]],"date-time":"2026-09-05T05:16:03Z","timestamp":1788585363103,"version":"build-2803163510"},"reference-count":45,"publisher":"Wiley","license":[{"start":{"date-parts":[[2026,9,4]],"date-time":"2026-09-04T00:00:00Z","timestamp":1788480000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,9,4]],"date-time":"2026-09-04T00:00:00Z","timestamp":1788480000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Fish Diseases"],"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    This study provides a detailed pathological characterization of skeletal neoplasms in the Indian oil sardine (\n                    <jats:styled-content style=\"fixed-case\">\n                      <jats:italic>Sardinella longiceps<\/jats:italic>\n                    <\/jats:styled-content>\n                    ) from the southeast coast of India. A total of 237,370 landed fish examined at Parangipettai landing center between 2022 and 2024 formed the surveillance population, among which 721 tumour cases were documented. The overall apparent prevalence of grossly detected tumour cases among landed fish examined was 0.30%, with seasonal values ranging from 0.02% during monsoon to 0.72% during summer. Among the tumour\u2010bearing fish, 136 lesions showed skeletal involvement and constituted the focus of the present study. Grossly, these lesions appeared as firm, irregular bony swellings involving predominantly cranial and fin\u2010associated skeletal regions, with lesion diameters ranging from 1.5 to 14.5\u2009mm. Radiographic examination of skeletal cases demonstrated well\u2010defined radiopaque lesions consistent with mineralized skeletal proliferation. Of the 136 skeletal lesions, 112 were suitable for histopathological examination. Histologically, 97 lesions (86.61%) were classified as compact (ivory) osteoma, 12 (10.71%) as cancellous osteoma, and 3 (2.68%) as chondrosarcoma. Osteomas were characterized by well\u2010differentiated mature lamellar bone without cytological atypia or malignant features, whereas chondrosarcomas exhibited increased cellularity, nuclear atypia, a lobulated chondroid matrix, and focal infiltrative growth within the available sections. Because complete tumour margins and surrounding tissues were not available in all chondrosarcoma cases, the extent of invasion could not be comprehensively assessed. These findings provide baseline pathological evidence of skeletal neoplasia in\n                    <jats:styled-content style=\"fixed-case\">\n                      <jats:italic>S.\u2009longiceps<\/jats:italic>\n                    <\/jats:styled-content>\n                    and support continued pathological surveillance and further investigation into the biological and environmental factors potentially associated with tumour development in wild marine fish.\n                  <\/jats:p>","DOI":"10.1111\/jfd.70285","type":"journal-article","created":{"date-parts":[[2026,9,5]],"date-time":"2026-09-05T04:33:40Z","timestamp":1788582820000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Neoplastic Bone Lesions in Indian Oil Sardine (\n                    <scp>\n                      <i>Sardinella longiceps<\/i>\n                    <\/scp>\n                    ): Apparent Prevalence, Morphological Diversity and Histopathological Insights"],"prefix":"10.1111","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8684-9133","authenticated-orcid":false,"given":"Singaravel","family":"Vijayapoopathi","sequence":"first","affiliation":[{"name":"Department of Biochemistry, Saveetha Institute of Basic Medical Science Saveetha Institute of Medical and Technical Sciences (SIMATS)  Chennai Tamil Nadu India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3808-3705","authenticated-orcid":false,"given":"Sakthivel","family":"Muthu","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Saveetha Medical College and Hospital Saveetha Institute of Medical and Technical Sciences (SIMATS)  Chennai Tamil Nadu India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5553-987X","authenticated-orcid":false,"given":"Gopalakrishnan","family":"Ayyaru","sequence":"additional","affiliation":[{"name":"Centre of Advanced Study in Marine Biology, Faculty of Marine Sciences Annamalai University  Parangipettai Tamil Nadu India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,9,4]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1289\/ehp.95103168"},{"key":"e_1_2_9_3_1","volume-title":"Assessment of the Fish Tumour Beneficial Use Impairment in Brown Bullhead (Ameiurus nebulosus) at Selected Great Lakes Areas of Concern (No. 2014\u20101105)","author":"Blazer V.","year":"2014"},{"issue":"5","key":"e_1_2_9_4_1","first-page":"37","article-title":"Some Interesting Case of Tumour in Marine Fishes","volume":"29","author":"Chavan B. B.","year":"2009","journal-title":"Fishing Chimes"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.3389\/fendo.2022.893699"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/jbmr.4256"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ecolind.2020.106544"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365\u20102761.2011.01299.x"},{"key":"e_1_2_9_9_1","first-page":"18","volume-title":"Fish Diseases and Disorders","author":"Grizzle J. M.","year":"2011"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cvex.2004.04.012"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/0048\u20109697(90)90362\u2010X"},{"issue":"3","key":"e_1_2_9_12_1","first-page":"411","article-title":"Sexual Ornamentation, Androgens and Papillomatosis in Male Roach (\n                     Rutilus rutilus\n                  )","volume":"5","author":"Kortet R.","year":"2003","journal-title":"Evolutionary Ecology Research"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.3354\/dao"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1095\u20108649.1992.tb02600.x"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365\u20102761.2002.00336.x"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ceja.2026.101052"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tice.2024.102629"},{"key":"e_1_2_9_18_1","first-page":"313","volume-title":"Systemic Pathology of Fish","author":"Martineau D.","year":"2006"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00051461"},{"key":"e_1_2_9_20_1","first-page":"173","volume-title":"Veterinary Research Forum","author":"Mesbah M.","year":"2016"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.1177\/0300985815593349"},{"key":"e_1_2_9_22_1","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1007\/978-3-319-04843-7_12","volume-title":"Current Advances in Osteosarcoma","author":"Mohseny A. B.","year":"2014"},{"key":"e_1_2_9_23_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40201\u2010026\u201000996\u2010y"},{"key":"e_1_2_9_24_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1749\u20106632.1977.tb19269.x"},{"key":"e_1_2_9_25_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12011\u2010025\u201004855\u2010z"},{"key":"e_1_2_9_26_1","doi-asserted-by":"publisher","DOI":"10.3354\/dao001123"},{"key":"e_1_2_9_27_1","first-page":"16","article-title":"Abnormalities in Indian Oil Sardine","volume":"235","author":"Retheesh T. B.","year":"2018","journal-title":"Marine Fisheries Information Service Technical and Extension Series"},{"key":"e_1_2_9_28_1","doi-asserted-by":"crossref","DOI":"10.1002\/9781118222942","volume-title":"Fish Pathology","author":"Roberts R. J.","year":"2012"},{"key":"e_1_2_9_29_1","volume-title":"Enigmatic Indian Oil Sardine: An Insight (No. 130)","author":"Rohit P.","year":"2018"},{"key":"e_1_2_9_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.marpolbul.2024.116139"},{"issue":"12","key":"e_1_2_9_31_1","first-page":"657","article-title":"Tumours of Fishes, Amphibians, and Reptiles","volume":"8","author":"Schlumberger H. G.","year":"1948","journal-title":"Cancer Research"},{"key":"e_1_2_9_32_1","first-page":"2327","article-title":"Prevalence and Histopathology of Branchioblastoma in \n                     Sardinella longiceps\n                   (Valenciennes 1847) of Southeast Coast of India","volume":"43","author":"Sinduja K.","year":"2014","journal-title":"Indian Journal of Marine Sciences"},{"key":"e_1_2_9_33_1","doi-asserted-by":"publisher","DOI":"10.3354\/dao03141"},{"key":"e_1_2_9_34_1","doi-asserted-by":"publisher","DOI":"10.12980\/JCLM.3.2015J5\u201042"},{"key":"e_1_2_9_35_1","doi-asserted-by":"publisher","DOI":"10.1111\/jai.13084"},{"key":"e_1_2_9_36_1","doi-asserted-by":"publisher","DOI":"10.1111\/jai.13168"},{"key":"e_1_2_9_37_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ecss.2026.110108"},{"key":"e_1_2_9_38_1","doi-asserted-by":"crossref","DOI":"10.1007\/s40009-026-02181-z","volume-title":"Ovarian Leiomyoma in Indian Oil Sardine, Sardinella longiceps Valenciennes 1847, the coastal waters off Parangipettai, Southeast coast of India","author":"Singaravel V.","year":"2026"},{"key":"e_1_2_9_39_1","volume-title":"Testicular Fibroma in Indian Oil Sardine, Sardinella longiceps Valenciennes, 1847, from Parangipettai, Southeast Coast of India","author":"Singaravel V.","year":"2026"},{"key":"e_1_2_9_40_1","doi-asserted-by":"publisher","DOI":"10.3147\/jsfp.45.84"},{"key":"e_1_2_9_41_1","doi-asserted-by":"publisher","DOI":"10.1002\/jmor.21782"},{"key":"e_1_2_9_42_1","doi-asserted-by":"publisher","DOI":"10.3354\/dao02691"},{"key":"e_1_2_9_43_1","first-page":"29","article-title":"Neoplasia in Oil Sardine From Palk Bay","volume":"231","author":"Vinothkumar R.","year":"2017","journal-title":"Marine Fisheries Information Service Technical and Extension Series"},{"key":"e_1_2_9_44_1","first-page":"59","article-title":"Neoplasia and Primitive Vertebrate Phylogeny: Echinoderms, Prevertebrates, and Fishes\u2014A Review","volume":"31","author":"Wellings S. R.","year":"1969","journal-title":"National Cancer Institute Monograph"},{"key":"e_1_2_9_45_1","first-page":"1","volume-title":"FAO Species Catalogue. Clupeoid Fishes of the World (Sub Order: Clupeioidei). An Annotated and Illustrated Catalogue of the Herrings, Sardines, Pilchards, Sprats, Shads, Anchovies and Wolf\u2010Herrings. Part 1 \u2013 Chirocentridae, Clupeidae and Pristigasteridae","author":"Whitehead P. J. P.","year":"1985"},{"key":"e_1_2_9_46_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cbpc.2008.12.002"}],"container-title":["Journal of Fish Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jfd.70285","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/jfd.70285","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jfd.70285","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,5]],"date-time":"2026-09-05T04:34:02Z","timestamp":1788582842000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/jfd.70285"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9,4]]},"references-count":45,"alternative-id":["10.1111\/jfd.70285"],"URL":"https:\/\/doi.org\/10.1111\/jfd.70285","archive":["Portico"],"relation":{},"ISSN":["0140-7775","1365-2761"],"issn-type":[{"value":"0140-7775","type":"print"},{"value":"1365-2761","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,9,4]]},"assertion":[{"value":"2026-07-23","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-08-28","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-09-04","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70285"}}