{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T10:16:09Z","timestamp":1760955369547},"reference-count":22,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2013,1,22]],"date-time":"2013-01-22T00:00:00Z","timestamp":1358812800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Gastro and Hepatol"],"published-print":{"date-parts":[[2013,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background and Aim<\/jats:title><jats:p>Hamartomatous polyposis syndromes (<jats:styled-content style=\"fixed-case\">HPS<\/jats:styled-content>) are a group of rare inherited autosomal dominant disorders. Small bowel polyposis is one of the manifestations of <jats:styled-content style=\"fixed-case\">HPS<\/jats:styled-content>. Double\u2010balloon enteroscopy (<jats:styled-content style=\"fixed-case\">DBE<\/jats:styled-content>) with polypectomy may obviate repeated small bowel surgeries for polyp intussusception, obstruction, or bleeding. The efficacy and safety of <jats:styled-content style=\"fixed-case\">DBE<\/jats:styled-content>\u2010assisted polypectomy in <jats:styled-content style=\"fixed-case\">HPS<\/jats:styled-content> patients with clinically significant small bowel polyposis were evaluated.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>All <jats:styled-content style=\"fixed-case\">HPS<\/jats:styled-content> patients who underwent <jats:styled-content style=\"fixed-case\">DBE<\/jats:styled-content> from <jats:styled-content style=\"fixed-case\">J<\/jats:styled-content>anuary 2007 to <jats:styled-content style=\"fixed-case\">A<\/jats:styled-content>pril 2011 were identified using a prospectively maintained database. Data on patient demographics, pre\u2010<jats:styled-content style=\"fixed-case\">DBE<\/jats:styled-content> radiological studies, polyp characteristics, procedural outcomes, and complications were abstracted.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Twenty\u2010two patients underwent a total of 34 <jats:styled-content style=\"fixed-case\">DBE<\/jats:styled-content> procedures. Pre\u2010<jats:styled-content style=\"fixed-case\">DBE<\/jats:styled-content> imaging included computed tomography enterography (<jats:italic>n<\/jats:italic>\u2009=\u200915), computed tomography enteroclysis (<jats:italic>n<\/jats:italic>\u2009=\u20095), small bowel follow\u2010through (<jats:italic>n<\/jats:italic>\u2009=\u20091), and magnetic resonance enterography (<jats:italic>n<\/jats:italic>\u2009=\u20091). Any small bowel polyp \u2265\u20091\u2009cm in size on radiological imaging was referred for <jats:styled-content style=\"fixed-case\">DBE<\/jats:styled-content>\u2010assisted polypectomy. Antegrade and retrograde <jats:styled-content style=\"fixed-case\">DBE<\/jats:styled-content> were successful in reaching and resecting targeted polyps in 90% (18\/20) and 71.4% (10\/14) of procedures, respectively. The overall success rate for <jats:styled-content style=\"fixed-case\">DBE<\/jats:styled-content>\u2010assisted polypectomy was 82.3% (95% confidence interval: 66.5\u201391.6%). The median size of resected polyps was 2\u2009cm (range 1\u20135\u2009cm) and all were hamartomas. Minor adverse events occurred in four (11.8%) procedures, including abdominal pain (<jats:italic>n<\/jats:italic>\u2009=\u20092), immediate post\u2010polypectomy bleeding (<jats:italic>n<\/jats:italic>\u2009=\u20091), and self\u2010limited hematochezia (<jats:italic>n<\/jats:italic>\u2009=\u20091).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p><jats:styled-content style=\"fixed-case\">DBE<\/jats:styled-content>\u2010assisted polypectomy was successful in over 80% of <jats:styled-content style=\"fixed-case\">HPS<\/jats:styled-content> patients with an acceptable margin of safety. To the knowledge of the authors, this is one of the largest single\u2010center studies to report on the performance and safety of <jats:styled-content style=\"fixed-case\">DBE<\/jats:styled-content>\u2010assisted polypectomy in <jats:styled-content style=\"fixed-case\">HPS<\/jats:styled-content> patients.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jgh.12058","type":"journal-article","created":{"date-parts":[[2012,11,29]],"date-time":"2012-11-29T01:02:29Z","timestamp":1354150949000},"page":"268-273","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Performance of double\u2010balloon enteroscopy for the management of small bowel polyps in hamartomatous polyposis syndromes"],"prefix":"10.1111","volume":"28","author":[{"given":"Emmanuel C","family":"Gorospe","sequence":"first","affiliation":[{"name":"Division of Gastroenterology and Hepatology Mayo Clinic  Rochester Minnesota USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jeffrey A","family":"Alexander","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology and Hepatology Mayo Clinic  Rochester Minnesota USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David H","family":"Bruining","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology and Hepatology Mayo Clinic  Rochester Minnesota USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elizabeth","family":"Rajan","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology and Hepatology Mayo Clinic  Rochester Minnesota USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Louis\u2010Michel","family":"Wong Kee Song","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology and Hepatology Mayo Clinic  Rochester Minnesota USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2013,1,22]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1053\/gast.2000.20228"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10434-001-0319-7"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.onc.1207714"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cgh.2005.11.005"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005176-200408000-00027"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.gie.2009.11.005"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00464-009-0868-6"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.gie.2006.05.031"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.gie.2011.04.001"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10620-010-1464-2"},{"key":"e_1_2_5_12_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-2004-826177"},{"key":"e_1_2_5_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bpg.2009.02.007"},{"key":"e_1_2_5_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-1746.2005.03865.x"},{"key":"e_1_2_5_15_1","doi-asserted-by":"publisher","DOI":"10.1093\/hmg\/6.8.1383"},{"key":"e_1_2_5_16_1","doi-asserted-by":"publisher","DOI":"10.4065\/mcp.2010.0816"},{"key":"e_1_2_5_17_1","doi-asserted-by":"publisher","DOI":"10.1067\/mge.2001.112181"},{"key":"e_1_2_5_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.gie.2010.08.018"},{"key":"e_1_2_5_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.gie.2009.11.045"},{"key":"e_1_2_5_20_1","doi-asserted-by":"publisher","DOI":"10.1136\/adc.2011.212563.30"},{"key":"e_1_2_5_21_1","first-page":"56","article-title":"Double balloon enteroscopy in children: diagnosis, treatment, and safety","volume":"16","author":"Thomson M","year":"2010","journal-title":"World J. Gastroenterol."},{"key":"e_1_2_5_22_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0030-1256249"},{"key":"e_1_2_5_23_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0030-1255727"}],"container-title":["Journal of Gastroenterology and Hepatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fjgh.12058","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fjgh.12058","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jgh.12058","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,15]],"date-time":"2023-10-15T03:08:27Z","timestamp":1697339307000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/jgh.12058"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,1,22]]},"references-count":22,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2013,2]]}},"alternative-id":["10.1111\/jgh.12058"],"URL":"https:\/\/doi.org\/10.1111\/jgh.12058","archive":["Portico"],"relation":{},"ISSN":["0815-9319","1440-1746"],"issn-type":[{"value":"0815-9319","type":"print"},{"value":"1440-1746","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,1,22]]},"assertion":[{"value":"2012-10-11","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2013-01-22","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}