{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,13]],"date-time":"2026-03-13T05:07:32Z","timestamp":1773378452354,"version":"3.50.1"},"reference-count":21,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2013,1,22]],"date-time":"2013-01-22T00:00:00Z","timestamp":1358812800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Gastro and Hepatol"],"published-print":{"date-parts":[[2013,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background and Aim<\/jats:title><jats:p>Despite remarkable advances in diagnostic modalities, preoperative assessment of the local tumor extent in esophageal cancer is still very difficult. The aim of this study was to evaluate the predictive value of the computed tomography (<jats:styled-content style=\"fixed-case\">CT<\/jats:styled-content>) attenuation value between the tumor and the aorta for esophageal cancer.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Consecutive <jats:styled-content style=\"fixed-case\">CT<\/jats:styled-content> values were determined between the center of the tumor and the center of the aorta. The distance between the intersection of the average <jats:styled-content style=\"fixed-case\">CT<\/jats:styled-content> attenuation value of the tumor using the lower <jats:styled-content style=\"fixed-case\">CT<\/jats:styled-content> attenuation value of the inclusion tissues (<jats:styled-content style=\"fixed-case\">T<\/jats:styled-content>\u2013<jats:styled-content style=\"fixed-case\">A<\/jats:styled-content> distance) was determined. The minimal <jats:styled-content style=\"fixed-case\">CT<\/jats:styled-content> attenuation value and the overall circumference of contact area (<jats:styled-content style=\"fixed-case\">P<\/jats:styled-content>icus' angle) were also determined. This study included 101 patients suspected of having a tumor invading the adventitia and evaluated the capacity of these parameters for predicting the aortic invasion.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The T\u2013A distance in patients who were diagnosed without aortic invasion was significantly longer than patients who were pathologically confirmed to have invasion to the aortic wall [<jats:styled-content style=\"fixed-case\">pT<\/jats:styled-content>4(<jats:styled-content style=\"fixed-case\">Ao<\/jats:styled-content>)] (<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.05). The minimal <jats:styled-content style=\"fixed-case\">CT<\/jats:styled-content> attenuation value in patients without aortic invasion was significantly lower than <jats:styled-content style=\"fixed-case\">pT<\/jats:styled-content>4(<jats:styled-content style=\"fixed-case\">Ao<\/jats:styled-content>) patients (<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.05), although such a difference was not observed for the Picus' angle. The <jats:styled-content style=\"fixed-case\">T<\/jats:styled-content>\u2013<jats:styled-content style=\"fixed-case\">A<\/jats:styled-content> distance (1.3\u2009mm &gt;) is the most reliable feature for predicting the aortic invasion, according to the results of the area under the receiver operating characteristic curve.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The assessment of the <jats:styled-content style=\"fixed-case\">T<\/jats:styled-content>\u2013<jats:styled-content style=\"fixed-case\">A<\/jats:styled-content> distance is simple and objective, and it can help prevent unnecessary surgery in patients with inoperable tumors.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jgh.12064","type":"journal-article","created":{"date-parts":[[2012,11,29]],"date-time":"2012-11-29T01:05:00Z","timestamp":1354151100000},"page":"297-302","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Distance between the esophageal tumor and the aorta measured by using the contrast\u2010enhanced attenuation on computed tomography for predicting this tumor invading aorta"],"prefix":"10.1111","volume":"28","author":[{"given":"Hironori","family":"Tsujimoto","sequence":"first","affiliation":[{"name":"Department of Surgery National Defense Medical College  Tokorozawa Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yusuke","family":"Matsumoto","sequence":"additional","affiliation":[{"name":"Department of Surgery National Defense Medical College  Tokorozawa Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Isao","family":"Kumano","sequence":"additional","affiliation":[{"name":"Department of Surgery National Defense Medical College  Tokorozawa Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Risa","family":"Takahata","sequence":"additional","affiliation":[{"name":"Department of Surgery National Defense Medical College  Tokorozawa Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kazumichi","family":"Yoshida","sequence":"additional","affiliation":[{"name":"Department of Surgery National Defense Medical College  Tokorozawa Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroyuki","family":"Horiguchi","sequence":"additional","affiliation":[{"name":"Department of Surgery National Defense Medical College  Tokorozawa Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shinsuke","family":"Nomura","sequence":"additional","affiliation":[{"name":"Department of Surgery National Defense Medical College  Tokorozawa Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Satoshi","family":"Ono","sequence":"additional","affiliation":[{"name":"Department of Surgery National Defense Medical College  Tokorozawa Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Junji","family":"Yamamoto","sequence":"additional","affiliation":[{"name":"Department of Surgery National Defense Medical College  Tokorozawa Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kazuo","family":"Hase","sequence":"additional","affiliation":[{"name":"Department of Surgery National Defense Medical College  Tokorozawa Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2013,1,22]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1067\/mtc.2003.404"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejso.2010.05.011"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.2214\/AJR.07.3581"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1093\/jjco\/hyl096"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1148\/radiology.146.2.6849089"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/jso.21316"},{"key":"e_1_2_6_8_1","volume-title":"TNM Classification of Malignant Tumours","author":"Sobin LH","year":"2009"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1102\/1470-7330.2007.0017"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1148\/radiology.156.3.4023234"},{"key":"e_1_2_6_11_1","first-page":"127","article-title":"Computed tomographic staging of esophageal cancer and prognosis","volume":"19","author":"Ampil FL","year":"2001","journal-title":"Radiat. 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