{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T08:37:49Z","timestamp":1791189469089,"version":"4.1.0"},"reference-count":28,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2013,3,25]],"date-time":"2013-03-25T00:00:00Z","timestamp":1364169600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Gastro and Hepatol"],"published-print":{"date-parts":[[2013,4]]},"abstract":"Abstract<\/jats:title>Background and Aims<\/jats:title>The apolipoprotein B<\/jats:styled-content>\/AI<\/jats:styled-content> (ApoB<\/jats:styled-content>\/AI<\/jats:styled-content>) ratio is a strong new risk factor for cardiovascular (CV<\/jats:styled-content>) disease. Although recent reports have shown the effects of non\u2010alcoholic fatty liver disease (NAFLD<\/jats:styled-content>) on CV<\/jats:styled-content> disease, NAFLD<\/jats:styled-content> is under\u2010recognized as a predictable risk factor for CV<\/jats:styled-content> disease. This study was performed to assess the independent association between ApoB<\/jats:styled-content>\/AI<\/jats:styled-content> ratio and NAFLD<\/jats:styled-content>.<\/jats:p><\/jats:sec>Methods<\/jats:title>This cross\u2010sectional study was performed in 9162 subjects who participated in a health checkup program in S<\/jats:styled-content>outh K<\/jats:styled-content>orea in 2009. The presence of NAFLD<\/jats:styled-content> was defined by ultrasonographic examination. Logistic regression analysis was applied to estimate the association between ApoB<\/jats:styled-content>\/AI<\/jats:styled-content> ratio and NAFLD<\/jats:styled-content>. The odds ratio (OR<\/jats:styled-content>) and P<\/jats:italic> were estimated according to the categorized level of the ApoB<\/jats:styled-content>\/AI<\/jats:styled-content> ratio.<\/jats:p><\/jats:sec>Results<\/jats:title>The overall prevalence of NAFLD<\/jats:styled-content> was 27.9% (n<\/jats:italic>\u2009=\u20092554, 41.7% of the men, 10.8% of the women). Men had a 5.91\u2010fold (95% CI<\/jats:styled-content> 5.28\u20136.62) greater risk for NAFLD<\/jats:styled-content> than women. After adjusting for confounding factors, the ApoB<\/jats:styled-content>\/AI<\/jats:styled-content> ratio was more closely associated with the prevalence of NAFLD<\/jats:styled-content> than with any other lipid profiles (OR<\/jats:styled-content> 8.537 in men, 16.6 in women). NAFLD<\/jats:styled-content> risk increased as the quartiles of the ApoB<\/jats:styled-content>\/AI<\/jats:styled-content> ratio increased from the first to the fourth quartile (OR<\/jats:styled-content> 1.359, 2.173 and 3.124, P<\/jats:styled-content><\/jats:italic> for trend\u2009<\u20090.001).<\/jats:p><\/jats:sec>Conclusion<\/jats:title>The ApoB<\/jats:styled-content>\/AI<\/jats:styled-content> ratio was associated with the prevalence of NAFLD<\/jats:styled-content> in nondiabetic subjects and was independent of obesity and other metabolic components. This result suggests that NAFLD<\/jats:styled-content> may provide additional information for atherosclerosis progression and CV<\/jats:styled-content> risks.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jgh.12077","type":"journal-article","created":{"date-parts":[[2012,12,6]],"date-time":"2012-12-06T13:49:29Z","timestamp":1354801769000},"page":"678-683","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":41,"title":["Apolipoprotein B<\/scp>\/AI<\/scp> ratio is independently associated with non\u2010alcoholic fatty liver disease in nondiabetic subjects"],"prefix":"10.1111","volume":"28","author":[{"given":"Young Gil","family":"Choe","sequence":"first","affiliation":[{"name":"Division of Gastroenterology and Hepatology, Department of Internal Medicine Kangbuk Samsung Hospital Sungkyunkwan University School of Medicine 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Joo","family":"Kim","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology and Hepatology, Department of Internal Medicine Kangbuk Samsung Hospital Sungkyunkwan University School of Medicine Seoul"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Woo Kyu","family":"Jeon","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology and Hepatology, Department of Internal Medicine Kangbuk Samsung Hospital Sungkyunkwan University School of Medicine Seoul"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Byung Ik","family":"Kim","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology and Hepatology, Department of Internal Medicine Kangbuk Samsung Hospital Sungkyunkwan University School of Medicine 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