{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,6]],"date-time":"2025-12-06T04:56:07Z","timestamp":1764996967603},"reference-count":39,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2013,3,25]],"date-time":"2013-03-25T00:00:00Z","timestamp":1364169600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Gastro and Hepatol"],"published-print":{"date-parts":[[2013,4]]},"abstract":"Abstract<\/jats:title>Background and Aims<\/jats:title>The J<\/jats:styled-content>apan S<\/jats:styled-content>ociety for D<\/jats:styled-content>ialysis T<\/jats:styled-content>herapy established \u201cG<\/jats:styled-content>uidelines for the T<\/jats:styled-content>reatment of H<\/jats:styled-content>epatitis C V<\/jats:styled-content>irus I<\/jats:styled-content>nfection in D<\/jats:styled-content>ialysis P<\/jats:styled-content>atients.\u201d We evaluated the status of HCV<\/jats:styled-content> infection and the treatment of hemodialysis patients in G<\/jats:styled-content>unma prefecture.<\/jats:p><\/jats:sec>Methods<\/jats:title>Questionnaires concerning the infection rate, recognition of the guidelines, and treatment status were sent to all 64 hospitals\/clinics that had hemodialysis systems in G<\/jats:styled-content>unma prefecture. The hepatitis C<\/jats:styled-content> virus\u2010infected hemodialysis patients who received pegylated interferon (peg\u2010IFN<\/jats:styled-content>) were analyzed at G<\/jats:styled-content>unma U<\/jats:styled-content>niversity H<\/jats:styled-content>ospital.<\/jats:p><\/jats:sec>Results<\/jats:title>The positive rate for hepatitis C<\/jats:styled-content> virus antibody was 256\/2582 hemodialysis patients (9.9%). The positive rate varied between institutions (range 0\u201340.0%; median 9.0%). All institutes recognized the establishment of the guidelines. Conventional or peg\u2010IFN<\/jats:styled-content> treatment was being given at 37.5% of the institutions. The other 62.5% institutions answered that they intended to provide the treatment in the future if collaboration with a hepatologist could be arranged. The most common answers regarding the indication for IFN<\/jats:styled-content> treatment were as follows: few complications, under 60 years of age, more than 10 years of survival expected on hemodialysis. Eighteen patients received peg\u2010IFN<\/jats:styled-content> treatment. The sustained virological response rate of all patients was 33.3%, 0% in 1b\/high viral titer, 50% in genotype 2, and 100% in genotype 2\/low viral titer. The sustained virological response rate was worse in the patients with 1b\/high viral load and diabetic nephropathy (P<\/jats:italic>\u2009<\u20090.05).<\/jats:p><\/jats:sec>Conclusions<\/jats:title>Recognition of the publication of the guidelines was high. However, the number of patients treated with peg\u2010IFN<\/jats:styled-content> was still low. Further enlightenment and cooperation between hemodialysis teams and hepatologists are therefore needed.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jgh.12118","type":"journal-article","created":{"date-parts":[[2013,1,10]],"date-time":"2013-01-10T05:58:38Z","timestamp":1357797518000},"page":"690-699","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Interferon treatment for patients with chronic hepatitis C<\/scp> complicated with chronic renal failure receiving hemodialysis"],"prefix":"10.1111","volume":"28","author":[{"given":"Akira","family":"Kojima","sequence":"first","affiliation":[{"name":"Department of Medicine and Molecular Science Gunma University Graduate School of Medicine Maebashi"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Satoru","family":"Kakizaki","sequence":"additional","affiliation":[{"name":"Department of Medicine and Molecular Science Gunma University Graduate School of Medicine Maebashi"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ken\u2010ichi","family":"Hosonuma","sequence":"additional","affiliation":[{"name":"Department of Medicine and Molecular Science Gunma University Graduate School of Medicine Maebashi"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuichi","family":"Yamazaki","sequence":"additional","affiliation":[{"name":"Department of Medicine and Molecular Science Gunma University Graduate School of Medicine Maebashi"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Norio","family":"Horiguchi","sequence":"additional","affiliation":[{"name":"Department of Medicine and Molecular Science Gunma University Graduate School of Medicine Maebashi"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ken","family":"Sato","sequence":"additional","affiliation":[{"name":"Department of Medicine and Molecular Science Gunma University Graduate School of Medicine Maebashi"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tokuyuki","family":"Kitahara","sequence":"additional","affiliation":[{"name":"Department of Nephrology Shibukawa Central Hospital Shibukawa Gunma Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masatomo","family":"Mori","sequence":"additional","affiliation":[{"name":"Department of Medicine and Molecular Science Gunma University Graduate School of Medicine Maebashi"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2013,3,25]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-1746.2010.06488.x"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1572-0241.2001.03701.x"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1086\/315869"},{"key":"e_1_2_5_5_1","first-page":"322","article-title":"Results of a national epidemiological investigation on HCV infection among dialysis patients (survey by the Italian branch of EDTNA\/ERCA)","volume":"12","author":"Lombardi M","year":"1999","journal-title":"J. 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