{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T05:43:59Z","timestamp":1777355039681,"version":"3.51.4"},"reference-count":32,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2013,5,22]],"date-time":"2013-05-22T00:00:00Z","timestamp":1369180800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Gastro and Hepatol"],"published-print":{"date-parts":[[2013,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background and Aim<\/jats:title><jats:p>The clinical features and etiology of <jats:styled-content style=\"fixed-case\">B<\/jats:styled-content>udd\u2013<jats:styled-content style=\"fixed-case\">C<\/jats:styled-content>hiari syndrome (<jats:styled-content style=\"fixed-case\">BCS<\/jats:styled-content>) vary from region to region, and there is lack of large sample studies about <jats:styled-content style=\"fixed-case\">BCS<\/jats:styled-content> in <jats:styled-content style=\"fixed-case\">C<\/jats:styled-content>hina. The aim of the present study was to study the clinical features and etiology of patients with incident <jats:styled-content style=\"fixed-case\">BCS<\/jats:styled-content> in <jats:styled-content style=\"fixed-case\">C<\/jats:styled-content>hina prospectively.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A consecutive case series of patients with incident <jats:styled-content style=\"fixed-case\">BCS<\/jats:styled-content> who were diagnosed in the <jats:styled-content style=\"fixed-case\">A<\/jats:styled-content>ffiliated <jats:styled-content style=\"fixed-case\">H<\/jats:styled-content>ospital of <jats:styled-content style=\"fixed-case\">X<\/jats:styled-content>uzhou <jats:styled-content style=\"fixed-case\">M<\/jats:styled-content>edical <jats:styled-content style=\"fixed-case\">C<\/jats:styled-content>ollege (<jats:styled-content style=\"fixed-case\">J<\/jats:styled-content>iangsu, <jats:styled-content style=\"fixed-case\">C<\/jats:styled-content>hina) were enrolled from <jats:styled-content style=\"fixed-case\">S<\/jats:styled-content>eptember 2010 to <jats:styled-content style=\"fixed-case\">D<\/jats:styled-content>ecember 2011. All of the patients had continuous follow\u2010ups to record the symptoms, body features, laboratory and radiology findings, and treatment methods through <jats:styled-content style=\"fixed-case\">M<\/jats:styled-content>ay 2012.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 145 incident cases of <jats:styled-content style=\"fixed-case\">BCS<\/jats:styled-content> were identified. <jats:styled-content style=\"fixed-case\">BCS<\/jats:styled-content> was caused by hepatic venous obstruction in 31% of the patients, inferior vena cava obstruction in 6% of the patients, and 63% suffered from a combination of the two conditions. At least one etiological factor was present in 82% of the patients, with the most common being membranous obstruction (61%). Only 5% of the patients had myeloproliferative neoplasms with a JAK2 V617F mutation, and none of the patients had a factor <jats:styled-content style=\"fixed-case\">V<\/jats:styled-content> Leiden mutation. Eighteen months after a percutaneous transluminal angioplasty was performed, the survival rate and the asymptomatic survival rate were 99% (95% confidence interval, 95\u2013100%) and 93% (95% confidence interval, 89\u201398%), respectively.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The most prevalent etiological factor for <jats:styled-content style=\"fixed-case\">BCS<\/jats:styled-content> in <jats:styled-content style=\"fixed-case\">C<\/jats:styled-content>hina is membranous obstruction. Moreover, most Chinese patients with chronic <jats:styled-content style=\"fixed-case\">BCS<\/jats:styled-content> are treated with percutaneous transluminal angioplasty and have an excellent clinical outcome.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jgh.12140","type":"journal-article","created":{"date-parts":[[2013,2,21]],"date-time":"2013-02-21T07:58:55Z","timestamp":1361433535000},"page":"1061-1067","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":64,"title":["Clinical features and etiology of <scp>B<\/scp>udd\u2013<scp>C<\/scp>hiari syndrome in <scp>C<\/scp>hinese patients: A single\u2010center study"],"prefix":"10.1111","volume":"28","author":[{"given":"Delei","family":"Cheng","sequence":"first","affiliation":[{"name":"Department of Interventional Radiology Affiliated Hospital of Xuzhou Medical College  China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hao","family":"Xu","sequence":"additional","affiliation":[{"name":"Department of Interventional Radiology Affiliated Hospital of Xuzhou Medical College  China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhao\u2010jun","family":"Lu","sequence":"additional","affiliation":[{"name":"Division of Epidemiology Xuzhou Medical College  Xuzhou Jiangsu China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rong","family":"Hua","sequence":"additional","affiliation":[{"name":"Department of Radiology Affiliated Hospital of Xuzhou Medical College  China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Huan","family":"Qiu","sequence":"additional","affiliation":[{"name":"Department of Ultrasound Affiliated Hospital of Xuzhou Medical College  China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hongtao","family":"Du","sequence":"additional","affiliation":[{"name":"Department of Radiology Affiliated Hospital of Xuzhou Medical College  China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xinjian","family":"Xu","sequence":"additional","affiliation":[{"name":"Department of Interventional Radiology Affiliated Hospital of Xuzhou Medical College  China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jing","family":"Zhang","sequence":"additional","affiliation":[{"name":"Division of Epidemiology Xuzhou Medical College  Xuzhou Jiangsu China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2013,5,22]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2008.10.007"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0028-1085094"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/hep.20064"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-151-3-200908040-00004"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1478-3231.2008.01838.x"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0168-8278(12)60004-X"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2011-09-376517"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1186\/1752-1947-6-102"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2007-11-125328"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-1746.1996.tb00056.x"},{"key":"e_1_2_5_12_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1440-1746.2000.02157.x"},{"key":"e_1_2_5_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1445-2197.2005.03135.x"},{"key":"e_1_2_5_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/0168-8278(95)80252-5"},{"key":"e_1_2_5_15_1","doi-asserted-by":"publisher","DOI":"10.1002\/hep.22772"},{"key":"e_1_2_5_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1572-0241.2006.00353.x"},{"key":"e_1_2_5_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1572-0241.1999.01152.x"},{"key":"e_1_2_5_18_1","doi-asserted-by":"publisher","DOI":"10.4065\/77.6.538"},{"key":"e_1_2_5_19_1","doi-asserted-by":"publisher","DOI":"10.1002\/1096-9098(200012)75:4<264::AID-JSO7>3.0.CO;2-Q"},{"key":"e_1_2_5_20_1","first-page":"2364","article-title":"Factor V Leiden mutation, prothrombin gene mutation, and deficiencies in coagulation inhibitors associated with Budd\u2010Chiari syndrome and portal vein thrombosis: results of a case\u2010control study","volume":"96","author":"Janssen HL","year":"2000","journal-title":"Blood"},{"key":"e_1_2_5_21_1","doi-asserted-by":"publisher","DOI":"10.1002\/hep.21435"},{"key":"e_1_2_5_22_1","first-page":"1440","article-title":"Prevalence of the JAK2V617F mutation in Chinese patients with Budd\u2010Chiari syndrome and portal vein thrombosis\u2014A prospective study","volume":"6","author":"Qi X","year":"2011","journal-title":"J. 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